AU5105598A - Indene inhibitors of cox-2 - Google Patents

Indene inhibitors of cox-2

Info

Publication number
AU5105598A
AU5105598A AU51055/98A AU5105598A AU5105598A AU 5105598 A AU5105598 A AU 5105598A AU 51055/98 A AU51055/98 A AU 51055/98A AU 5105598 A AU5105598 A AU 5105598A AU 5105598 A AU5105598 A AU 5105598A
Authority
AU
Australia
Prior art keywords
carbon atoms
hydrogen
alkyl
halogen
fluoroalkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51055/98A
Other languages
English (en)
Inventor
Amedeo Arturo Failli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of AU5105598A publication Critical patent/AU5105598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
AU51055/98A 1996-11-12 1997-11-10 Indene inhibitors of cox-2 Abandoned AU5105598A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74794896A 1996-11-12 1996-11-12
US08747948 1996-11-12
PCT/US1997/020231 WO1998021195A1 (en) 1996-11-12 1997-11-10 Indene inhibitors of cox-2

Publications (1)

Publication Number Publication Date
AU5105598A true AU5105598A (en) 1998-06-03

Family

ID=25007366

Family Applications (1)

Application Number Title Priority Date Filing Date
AU51055/98A Abandoned AU5105598A (en) 1996-11-12 1997-11-10 Indene inhibitors of cox-2

Country Status (9)

Country Link
EP (1) EP0948493A1 (hu)
JP (1) JP2001504118A (hu)
KR (1) KR20000053227A (hu)
CN (1) CN1237162A (hu)
AU (1) AU5105598A (hu)
BR (1) BR9713346A (hu)
CA (1) CA2269035A1 (hu)
HU (1) HUP9904696A2 (hu)
WO (1) WO1998021195A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150368A0 (en) 1999-12-23 2002-12-01 Nitromed Inc Nitrosated and nitrosylated cyclooxygenase-2-inhibitors, compositions and methods of use
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
WO2007081694A2 (en) 2006-01-04 2007-07-19 Southern Research Institute Derivatives of sulindac, use thereof and preparation thereof
CN104592091B (zh) 2015-01-27 2017-07-04 冉瑞琼 一种含吲哚乙酸核心结构的化合物及其应用
CA3209491A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease
CA3235127A1 (en) * 2021-10-15 2023-04-20 Yao XU 2,3-dimethoxy-5-methyl-1,4-benzoquinone alkyl alcohol derivative and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3647858A (en) * 1970-05-01 1972-03-07 Merck & Co Inc Process for preparing 1-benzylidene-3-indenyl acetic acids
MX9302419A (es) * 1992-04-28 1994-03-31 American Home Prod Derivados de acido tetronico, tiotetronico y tetramico.
GB9403857D0 (en) * 1994-03-01 1994-04-20 Scotia Holdings Plc Fatty acid derivatives

Also Published As

Publication number Publication date
EP0948493A1 (en) 1999-10-13
KR20000053227A (ko) 2000-08-25
WO1998021195A1 (en) 1998-05-22
HUP9904696A2 (hu) 2000-05-28
CA2269035A1 (en) 1998-05-22
JP2001504118A (ja) 2001-03-27
BR9713346A (pt) 2000-05-09
CN1237162A (zh) 1999-12-01

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period