AU462431B2 - Process of separating optical, geometric structural isomers andthe compounds usedfor - Google Patents

Process of separating optical, geometric structural isomers andthe compounds usedfor

Info

Publication number
AU462431B2
AU462431B2 AU39611/72A AU3961172A AU462431B2 AU 462431 B2 AU462431 B2 AU 462431B2 AU 39611/72 A AU39611/72 A AU 39611/72A AU 3961172 A AU3961172 A AU 3961172A AU 462431 B2 AU462431 B2 AU 462431B2
Authority
AU
Australia
Prior art keywords
usedfor
structural isomers
separating optical
geometric structural
andthe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU39611/72A
Other languages
English (en)
Other versions
AU3961172A (en
Inventor
VITERBI and JEANJACQUES RENE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Merrell SpA
Original Assignee
Richardson Merrell SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell SpA filed Critical Richardson Merrell SpA
Publication of AU3961172A publication Critical patent/AU3961172A/en
Application granted granted Critical
Publication of AU462431B2 publication Critical patent/AU462431B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
AU39611/72A 1971-03-18 1972-03-03 Process of separating optical, geometric structural isomers andthe compounds usedfor Expired AU462431B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49167/71A IT951631B (it) 1971-03-18 1971-03-18 Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi

Publications (2)

Publication Number Publication Date
AU3961172A AU3961172A (en) 1973-09-06
AU462431B2 true AU462431B2 (en) 1975-06-09

Family

ID=11269830

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39611/72A Expired AU462431B2 (en) 1971-03-18 1972-03-03 Process of separating optical, geometric structural isomers andthe compounds usedfor

Country Status (18)

Country Link
US (1) US3848030A (enExample)
JP (1) JPS5547013B1 (enExample)
AU (1) AU462431B2 (enExample)
BE (1) BE780887A (enExample)
CA (1) CA961500A (enExample)
CH (1) CH576921A5 (enExample)
DE (1) DE2212660C3 (enExample)
DK (1) DK139944B (enExample)
ES (1) ES400862A1 (enExample)
FR (1) FR2129741A5 (enExample)
GB (1) GB1360946A (enExample)
IL (1) IL38860A (enExample)
IT (1) IT951631B (enExample)
NL (1) NL7203574A (enExample)
NO (1) NO136357C (enExample)
PH (1) PH10768A (enExample)
SE (1) SE409323B (enExample)
ZA (1) ZA721297B (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143028A (en) * 1977-12-05 1979-03-06 Ciba-Geigy Corporation Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions
US5288914A (en) * 1984-08-27 1994-02-22 The Dow Chemical Company Poly(arylcyclobutenes)
NL8403224A (nl) * 1984-10-24 1986-05-16 Oce Andeno Bv Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
DE3940765A1 (de) * 1989-12-09 1991-06-13 Hoechst Ag Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester
KR100387459B1 (ko) * 1994-05-16 2003-11-20 메렐 파마슈티칼스 인크. 라세미성a-[4-(1,1-디메틸에틸)페닐]-4-(하이드록시디페닐메틸)-1-피페리딘부탄올및이의유도체화합물의광학분할법및이에유용한부분입체이성체염
JP4725757B2 (ja) * 1999-03-24 2011-07-13 東ソー株式会社 ビナフトールリン酸誘導体及びその利用
DE60008807T2 (de) * 1999-03-24 2005-01-13 Tosoh Corp., Shinnanyo Binaphtol-monophosphorsäurederivate und deren Verwendung
DE60026725T2 (de) * 1999-10-22 2006-09-07 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver
AU1303001A (en) * 1999-11-10 2001-06-06 Takeda Chemical Industries Ltd. Process for the production of optically active cyclic enaminone derivatives
US6391926B2 (en) 2000-03-13 2002-05-21 Tosoh Corporation Optically active phosphate derivative
ES2312593T3 (es) 2001-07-09 2009-03-01 Repros Therapeutics Inc. Procedimientos y materiales para el tratamiento de la deficiencia de testosterona en hombres.
WO2004096753A1 (ja) * 2003-04-25 2004-11-11 Toagosei Co., Ltd. キラルなブレンステッド酸による不斉合成用触媒および当該触媒を用いた不斉合成方法
US7229557B2 (en) * 2004-02-04 2007-06-12 Konec, Inc. Method to separate stereoisomers
US8420822B2 (en) * 2009-10-09 2013-04-16 Hetero Research Foundation Optical resolution of substituted 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
UA113324C2 (xx) 2012-08-21 2017-01-10 Склади транс-кломіфену та їх застосування
CA2889770A1 (en) 2012-11-02 2014-05-08 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
US9914696B2 (en) * 2014-03-11 2018-03-13 Repros Therapeutics Inc. Clomiphene synthesis using a single solvent
MX382930B (es) 2014-07-24 2025-03-13 Aspen Park Pharmaceuticals Inc Tratamiento con cis-clomifeno de sofocos y pérdida ósea inducidos por privación de andrógeno terapéutica.
EP3015453B1 (en) 2014-10-28 2016-10-12 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of Clomiphene
EP3015454A1 (en) * 2014-10-28 2016-05-04 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Stable solid form of trans-Clomiphene citrate
CN108463453A (zh) * 2016-04-22 2018-08-28 意大利合成制造有限公司 用于制备具有针状晶体习性的柠檬酸恩氯米芬的方法
TWI793165B (zh) 2017-09-11 2023-02-21 美商阿托薩醫療公司 製造及使用因多昔芬(endoxifen)之方法
FR3082842A1 (fr) * 2018-06-21 2019-12-27 Veru Inc. Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci
US12201591B2 (en) 2019-07-03 2025-01-21 Atossa Therapeutics, Inc. Sustained release compositions of endoxifen
CA3098552A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Processes for the preparation of zuclomiphene and intermediates thereof
CA3098725A1 (en) 2019-11-14 2021-05-14 Apotex Inc. Zuclpomiphene salts and crystalline forms thereof
CA3105944A1 (en) 2020-01-22 2021-07-22 Apotex Inc. Crystalline forms of zuclomiphene citrate
EP3907213A1 (en) 2020-05-04 2021-11-10 Pcas Processes for the production of isomerically pure or enriched cis-clomiphene
US11578025B2 (en) 2020-10-19 2023-02-14 Apotex Inc. Processes for the preparation of zuclomiphene intermediates

Also Published As

Publication number Publication date
AU3961172A (en) 1973-09-06
DE2212660A1 (de) 1972-09-28
ES400862A1 (es) 1976-04-16
CH576921A5 (enExample) 1976-06-30
BE780887A (fr) 1972-07-17
US3848030A (en) 1974-11-12
CA961500A (en) 1975-01-21
IL38860A0 (en) 1972-04-27
SE409323B (sv) 1979-08-13
DE2212660B2 (de) 1980-07-10
ZA721297B (en) 1973-03-28
JPS5547013B1 (enExample) 1980-11-27
PH10768A (en) 1977-09-05
IL38860A (en) 1975-06-25
IT951631B (it) 1973-07-10
DK139944C (enExample) 1979-10-22
GB1360946A (en) 1974-07-24
DE2212660C3 (de) 1981-09-24
NL7203574A (enExample) 1972-09-20
DK139944B (da) 1979-05-21
NO136357B (enExample) 1977-05-16
FR2129741A5 (enExample) 1972-10-27
NO136357C (no) 1977-08-24

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