AU4454597A - Novel benzofuran-4-carboxamides - Google Patents
Novel benzofuran-4-carboxamidesInfo
- Publication number
- AU4454597A AU4454597A AU44545/97A AU4454597A AU4454597A AU 4454597 A AU4454597 A AU 4454597A AU 44545/97 A AU44545/97 A AU 44545/97A AU 4454597 A AU4454597 A AU 4454597A AU 4454597 A AU4454597 A AU 4454597A
- Authority
- AU
- Australia
- Prior art keywords
- carboxamides
- novel benzofuran
- benzofuran
- novel
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- MZAUQUVYPHLLDF-UHFFFAOYSA-N 1-benzofuran-4-carboxamide Chemical class NC(=O)C1=CC=CC2=C1C=CO2 MZAUQUVYPHLLDF-UHFFFAOYSA-N 0.000 title 1
- PIEXCQIOSMOEOU-UHFFFAOYSA-N 1-bromo-3-chloro-5,5-dimethylimidazolidine-2,4-dione Chemical group CC1(C)N(Br)C(=O)N(Cl)C1=O PIEXCQIOSMOEOU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Table Devices Or Equipment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19633052 | 1996-08-19 | ||
| DE19633052 | 1996-08-19 | ||
| PCT/EP1997/004398 WO1998007715A1 (en) | 1996-08-19 | 1997-08-13 | Novel benzofuran-4-carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU4454597A true AU4454597A (en) | 1998-03-06 |
Family
ID=7802799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU44545/97A Abandoned AU4454597A (en) | 1996-08-19 | 1997-08-13 | Novel benzofuran-4-carboxamides |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6211203B1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP0923568B9 (cg-RX-API-DMAC10.html) |
| JP (1) | JP4309475B2 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE229516T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU4454597A (cg-RX-API-DMAC10.html) |
| CY (1) | CY2458B1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE69717827T2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK0923568T5 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2188983T4 (cg-RX-API-DMAC10.html) |
| PT (1) | PT923568E (cg-RX-API-DMAC10.html) |
| WO (1) | WO1998007715A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2252537A1 (en) * | 1996-05-20 | 1997-11-27 | Darwin Discovery Limited | Benzofuran carboxamides and their therapeutic use |
| CN1290266A (zh) * | 1998-02-09 | 2001-04-04 | 达尔文发现有限公司 | 苯并呋喃-4-甲酰胺和其治疗用途 |
| TW555759B (en) * | 1998-06-08 | 2003-10-01 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| IL140070A (en) | 1998-06-10 | 2004-06-20 | Altana Pharma Ag | History of benzamide and pharmaceutical preparations containing them |
| JP2002529444A (ja) * | 1998-11-12 | 2002-09-10 | アリアド・ファーマシューティカルズ・インコーポレイテッド | 二環式シグナル伝達阻害剤、それを含む組成物とその用途 |
| DE19924340A1 (de) | 1999-05-27 | 2000-11-30 | Basf Ag | Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren |
| SK287231B6 (sk) | 1999-08-21 | 2010-04-07 | Nycomed Gmbh | Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora |
| GB0003257D0 (en) | 2000-02-11 | 2000-04-05 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| WO2004087211A2 (en) | 2003-04-01 | 2004-10-14 | Applied Research Systems Ars Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| CA2620333A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| EP2314289A1 (en) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US7842713B2 (en) * | 2006-04-20 | 2010-11-30 | Pfizer Inc | Fused phenyl amido heterocyclic compounds |
| JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | 5ht受容体介在性の神経新生 |
| EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2009002496A (es) | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| CA2735184C (en) | 2008-09-11 | 2013-05-28 | Pfizer Inc. | Heteroaryls amide derivatives and their use as glucokinase activators |
| AR074760A1 (es) * | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| PL2406253T3 (pl) * | 2009-03-11 | 2013-10-31 | Pfizer | Pochodne benzofuranylu jako inhibitory glukokinazy |
| RU2446143C2 (ru) * | 2010-05-19 | 2012-03-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) | Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот |
| EP2582674B1 (en) * | 2010-06-16 | 2014-10-01 | Cymabay Therapeutics, Inc. | Gpr120 receptor agonists and uses thereof |
| US8299117B2 (en) | 2010-06-16 | 2012-10-30 | Metabolex Inc. | GPR120 receptor agonists and uses thereof |
| WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| AU2018363467B2 (en) | 2017-11-10 | 2023-09-07 | Jiangsu Hengrui Medicine Co., Ltd. | Method for preparing benzofuran derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL178314B1 (pl) * | 1993-07-02 | 2000-04-28 | Byk Gulden Lomberg Chem Fab | Benzamidy podstawione grupą fluoroalkoksylową, hamujące fosfodiesterazę cyklicznych nukleotydów, sposób ich otrzymywania i lek zawierający podstawione benzamidy |
| RU2138498C1 (ru) * | 1994-07-22 | 1999-09-27 | Бык Гульден Ломберг Хемише Фабрик Гмбх | Дигидробензофураны, способ их получения и фармацевтическая композиция на их основе |
| EP0771794B1 (en) * | 1995-05-19 | 2006-05-03 | Kyowa Hakko Kogyo Co., Ltd. | Oxygen-containing heterocyclic compounds |
| DE69620458T2 (de) * | 1995-12-05 | 2002-10-02 | Darwin Discovery Ltd., Cambridge | Benzofuran-carboxamide und -sulfonamide |
| CA2252537A1 (en) * | 1996-05-20 | 1997-11-27 | Darwin Discovery Limited | Benzofuran carboxamides and their therapeutic use |
-
1997
- 1997-08-13 AT AT97942858T patent/ATE229516T1/de not_active IP Right Cessation
- 1997-08-13 US US09/147,640 patent/US6211203B1/en not_active Expired - Lifetime
- 1997-08-13 PT PT97942858T patent/PT923568E/pt unknown
- 1997-08-13 ES ES97942858T patent/ES2188983T4/es not_active Expired - Lifetime
- 1997-08-13 AU AU44545/97A patent/AU4454597A/en not_active Abandoned
- 1997-08-13 WO PCT/EP1997/004398 patent/WO1998007715A1/en not_active Ceased
- 1997-08-13 EP EP97942858A patent/EP0923568B9/en not_active Expired - Lifetime
- 1997-08-13 DE DE69717827T patent/DE69717827T2/de not_active Expired - Lifetime
- 1997-08-13 JP JP51035698A patent/JP4309475B2/ja not_active Expired - Fee Related
- 1997-08-13 DK DK97942858T patent/DK0923568T5/da active
-
2004
- 2004-06-08 CY CY0400046A patent/CY2458B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998007715A1 (en) | 1998-02-26 |
| JP4309475B2 (ja) | 2009-08-05 |
| CY2458B1 (en) | 2005-06-03 |
| DK0923568T3 (da) | 2003-04-07 |
| US6211203B1 (en) | 2001-04-03 |
| ATE229516T1 (de) | 2002-12-15 |
| EP0923568A1 (en) | 1999-06-23 |
| PT923568E (pt) | 2003-04-30 |
| EP0923568B1 (en) | 2002-12-11 |
| DE69717827D1 (de) | 2003-01-23 |
| ES2188983T3 (es) | 2003-07-01 |
| DK0923568T5 (da) | 2003-11-03 |
| WO1998007715A9 (en) | 1999-04-29 |
| EP0923568B9 (en) | 2003-08-13 |
| DE69717827T2 (de) | 2003-09-04 |
| ES2188983T4 (es) | 2004-06-01 |
| JP2000516932A (ja) | 2000-12-19 |
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