AU3928999A - Novel n-oxides - Google Patents

Novel n-oxides

Info

Publication number
AU3928999A
AU3928999A AU39289/99A AU3928999A AU3928999A AU 3928999 A AU3928999 A AU 3928999A AU 39289/99 A AU39289/99 A AU 39289/99A AU 3928999 A AU3928999 A AU 3928999A AU 3928999 A AU3928999 A AU 3928999A
Authority
AU
Australia
Prior art keywords
oxides
novel
hand
pde3
pde4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU39289/99A
Other languages
English (en)
Inventor
Hermann Amschler
Thomas Bar
Rolf Beume
Hildegard Boss
Daniela Bundschuh
Dieter Flockerzi
Beate Gutterer
Armin Hatzelmann
Hans-Peter Kley
Thomas Martin
Wolf-Rudiger Ulrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of AU3928999A publication Critical patent/AU3928999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Glass Compositions (AREA)
AU39289/99A 1998-05-05 1999-04-27 Novel n-oxides Abandoned AU3928999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98108124 1998-05-05
EP98108124 1998-05-05
PCT/EP1999/002827 WO1999057118A1 (de) 1998-05-05 1999-04-27 Neue n-oxide

Publications (1)

Publication Number Publication Date
AU3928999A true AU3928999A (en) 1999-11-23

Family

ID=8231880

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39289/99A Abandoned AU3928999A (en) 1998-05-05 1999-04-27 Novel n-oxides

Country Status (12)

Country Link
US (1) US6306869B1 (enExample)
EP (1) EP1075477B1 (enExample)
JP (1) JP2002513793A (enExample)
AT (1) ATE234301T1 (enExample)
AU (1) AU3928999A (enExample)
CA (1) CA2330738A1 (enExample)
DE (1) DE59904535D1 (enExample)
DK (1) DK1075477T3 (enExample)
ES (1) ES2195571T3 (enExample)
PT (1) PT1075477E (enExample)
SI (1) SI1075477T1 (enExample)
WO (1) WO1999057118A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5970199A (en) 1998-08-31 2000-03-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine-n-oxides comprising a pde3 and pde4 inhibiting activity
SI1212089T1 (sl) * 1999-08-21 2006-08-31 Altana Pharma Ag Sinergisticna kombinacija roflumilasta in salmeterola
DE60133879D1 (de) 2000-01-11 2008-06-19 Nycomed Gmbh Phenanthridin -n- oxide
SI1377574T1 (enExample) * 2001-02-21 2005-08-31 Altana Pharma Ag
PL373598A1 (en) * 2002-08-17 2005-09-05 Altana Pharma Ag Novel benzonaphthyridines
AU2003255493B8 (en) * 2002-08-29 2009-03-26 Takeda Gmbh 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
JP4587295B2 (ja) * 2002-08-29 2010-11-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｐｄｅ４インヒビターとしての３−ヒドロキシ−６−フェニルフェナントリジン
DE60313331T2 (de) * 2002-09-04 2008-01-03 Nycomed Gmbh Neue benzonaphthyridine
US7470704B2 (en) 2002-09-04 2008-12-30 Nycomed Gmbh Benzonaphthyridines
IS7839A (is) * 2002-11-22 2004-05-23 Merck Frosst Canada Ltd. 4-oxó-1-(3-setið fenýl-1,4-díhýdró-1,8-naftýridín-3-karboxamíð fosfódíesterasa-4 hindrar
AU2005212857B2 (en) * 2004-02-18 2011-04-28 Takeda Gmbh Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (PDE) 4 inhibitors
SI2589599T1 (sl) 2004-03-03 2014-10-30 Takeda Gmbh Novi hidroksi-6-heteroarilfenantridini in njihova uporaba kot PDE4 inhibitorji
AR049419A1 (es) * 2004-03-03 2006-08-02 Altana Pharma Ag Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo
WO2005084104A2 (en) * 2004-03-09 2005-09-15 Altana Pharma Ag Novel isoamido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors
JP2007527900A (ja) * 2004-03-10 2007-10-04 アルタナ　ファルマ　アクチエンゲゼルシャフト チオ含有の新規のヒドロキシ−６−フェニルフェナントリジン及びｐｄｅ４インヒビターとしてのそれらの使用
AU2005219581A1 (en) * 2004-03-10 2005-09-15 Nycomed Gmbh Novel difluoroethoxy-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
AU2005221832A1 (en) * 2004-03-10 2005-09-22 Nycomed Gmbh Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors
AU2005223386A1 (en) 2004-03-17 2005-09-29 Nycomed Gmbh Novel N- (alkoxyalkyl) carbamoyl - substituted 6-phenyl-benzonaphthyridine derivatives and their use as PDE3/4 inhibitors
EP1791847A2 (en) 2004-09-08 2007-06-06 Altana Pharma AG Novel 3-thia-10-aza-phenanthrene derivatives
ES2365926T3 (es) * 2004-09-08 2011-10-13 Nycomed Gmbh 3-oxa-10-aza-fenantrenos como inhibidores de pde4 o pde3/4.
NZ560268A (en) 2005-03-02 2010-12-24 Nycomed Gmbh Novel salts of 6-heterocyclyl substituted hexahydrophenanthridine derivatives
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP1942879A1 (en) 2005-10-31 2008-07-16 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin
NZ334976A (en) 1996-11-11 2000-10-27 Byk Gulden Lomberg Chem Fab Benzonaphthyridine derivatives and their use for treating airway disorders and dermatoses

Also Published As

Publication number Publication date
PT1075477E (pt) 2003-07-31
JP2002513793A (ja) 2002-05-14
EP1075477A1 (de) 2001-02-14
US6306869B1 (en) 2001-10-23
DK1075477T3 (da) 2003-06-30
EP1075477B1 (de) 2003-03-12
CA2330738A1 (en) 1999-11-11
SI1075477T1 (en) 2003-08-31
ATE234301T1 (de) 2003-03-15
DE59904535D1 (de) 2003-04-17
WO1999057118A1 (de) 1999-11-11
ES2195571T3 (es) 2003-12-01

Similar Documents

Publication Publication Date Title
AU3928999A (en) Novel n-oxides
CA2297911A1 (en) Substituted 6-phenylphenanthridines
AU3328499A (en) Phthalazinone pde iii/iv inhibitors
PL334561A1 (en) Novel phtalysinones
YU19499A (sh) Benzonaftiridini kao bronhijalni terapeutici
WO2002102313A3 (en) Pyrimidine inhibitors of phosphodiesterase (pde) 7
MY135732A (en) 5,6-trimethylenepyrimidin - 4 - one compounds
ES2195785A1 (es) Nuevos derivados de piridazin-3(2h)-ona.
WO2003087088A3 (en) (condensed) pyrimidone and (condensed) pyridone compounds, processes for their preparation, and pharmaceutical compositions containing them
WO2004018465A3 (en) Benzonaphthyridines with pde 3/4 inhibiting activity
TR200400702T4 (tr) AMP özgü fosfodiesteraz inhibtörleri olarak 3-tiazol-4-il-pirolidin türevleri.
WO2005049581A8 (en) Pyridazin-3 (2h) -one derivatives and their use as pde4 inhibitors
PL338339A1 (en) Novel derivatives of tetrazole
DK1109810T3 (da) Benzonaphthydin-N-oxider med PDE3- og PDE4-inhiberende aktivitet
WO2002085906A3 (en) Phthalazinones derivatives useful as pde4/7 inhibitors
WO2001027118A3 (de) Bicyclische imidazo-5-yl-aminderivate
AU2002221753A1 (en) Novel 7-azaindoles, use thereof as phosphodiesterase 4 inhibitors and method for producing the same
AU2290000A (en) Phenanthridine-n-oxides with pde-iv inhibiting activity
PL341239A1 (en) Dihydrobenzofuranes
PT1086096E (pt) Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4
AU2904300A (en) Polysubstituted 6-phenylphenanthridines with pde-iv inhibiting activity
AU2107700A (en) Phenanthridine-n-oxides with pde-iv inhibiting activity
AU2289400A (en) 6-arylphenanthridines with pde-iv inhibiting activity
MXPA02012263A (es) 5-aminoalquil-pirazol[4,3-d]pirimidinas.
WO2002051848A3 (de) Sulfamidothienopyrimidine zur verwendung als phosphodiesterase v-hemmer

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase