AU3764693A - Phenol and pyridinol derivatives as lusitropic agents - Google Patents

Phenol and pyridinol derivatives as lusitropic agents

Info

Publication number
AU3764693A
AU3764693A AU37646/93A AU3764693A AU3764693A AU 3764693 A AU3764693 A AU 3764693A AU 37646/93 A AU37646/93 A AU 37646/93A AU 3764693 A AU3764693 A AU 3764693A AU 3764693 A AU3764693 A AU 3764693A
Authority
AU
Australia
Prior art keywords
naphthyl
formula
compound
oxo
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU37646/93A
Other languages
English (en)
Inventor
Philippe Lahouratate
Kenneth John Murray
Roderick Alan Porter
Brian Herbert Warrington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Laboratoires Pharmaceutiques
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU3764693A publication Critical patent/AU3764693A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU37646/93A 1992-03-27 1993-03-25 Phenol and pyridinol derivatives as lusitropic agents Abandoned AU3764693A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9203747 1992-03-27
FR9203747A FR2689012A1 (fr) 1992-03-27 1992-03-27 Utilisation de composés aryliques dans le traitement d'affections cardio-vasculaires.

Publications (1)

Publication Number Publication Date
AU3764693A true AU3764693A (en) 1993-11-08

Family

ID=9428178

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37646/93A Abandoned AU3764693A (en) 1992-03-27 1993-03-25 Phenol and pyridinol derivatives as lusitropic agents

Country Status (8)

Country Link
EP (1) EP0632724A1 (enrdf_load_stackoverflow)
JP (1) JPH07508707A (enrdf_load_stackoverflow)
KR (1) KR950700736A (enrdf_load_stackoverflow)
AU (1) AU3764693A (enrdf_load_stackoverflow)
CA (1) CA2132981A1 (enrdf_load_stackoverflow)
FR (1) FR2689012A1 (enrdf_load_stackoverflow)
TW (1) TW234086B (enrdf_load_stackoverflow)
WO (1) WO1993019754A1 (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753722A1 (fr) * 1996-09-26 1998-03-27 Smithkline Beecham Lab Procede de detection de modulateurs de relaxation cardiaque et modulateurs ainsi obtenus
TWI486165B (zh) 2011-02-15 2015-06-01 Univ China Medical 用於抑制血管狹窄之醫藥組合物及萃取物與該等之應用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ234186A (en) * 1989-07-07 1991-10-25 Janssen Pharmaceutica Nv Imidazo quinazolin-one derivatives and pharmaceutical compositions
WO1991017987A1 (en) * 1990-05-21 1991-11-28 Smith Kline & French Laboratories Limited Phenol and pyridinol derivatives as pharmaceuticals
CA2091989A1 (en) * 1990-09-28 1992-03-29 Roderick Alan Porter Phenylpyridinol derivatives as medicaments

Also Published As

Publication number Publication date
JPH07508707A (ja) 1995-09-28
KR950700736A (ko) 1995-02-20
TW234086B (enrdf_load_stackoverflow) 1994-11-11
CA2132981A1 (en) 1993-10-14
WO1993019754A1 (en) 1993-10-14
FR2689012A1 (fr) 1993-10-01
EP0632724A1 (en) 1995-01-11

Similar Documents

Publication Publication Date Title
DE3586543T2 (de) Diphosphonate und ihre verwendung in arzneimitteln.
US3261859A (en) Basically substituted phenyl acetonitrile compounds
US5583122A (en) Pharmaceutical compositions containing geminal diphosphonates
JP6173393B2 (ja) 変異cftrタンパク質の修飾因子としての化合物
HUT61729A (en) Process for producing dihydroisoquinoline derivatives and pharmaceutical compositions comprising such compounds
DE69726449T2 (de) Aminophosphonsäure-derivate als arzneimittel
DE69312984T2 (de) Substituierte Aminophosphonatderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JP2660086B2 (ja) 脳及び心機能障害改善剤
EP1268498A1 (en) Cardioprotective phosphonates and malonates
US4535073A (en) Antihypertensive phosphono derivatives of hantzsch dihydropyridines
JP4163007B2 (ja) カルバ環状ホスファチジン酸誘導体を含む癌転移抑制剤
DE69026964T2 (de) Gem-diphosphonsäuren, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
KR20200108330A (ko) 포스포르(포스포론)아미다타세탈 및 포스프(온)아탈세탈 화합물
KR20010070962A (ko) 유기 인 화합물 및 이의 용도
TWI223651B (en) Phosphonic acid derivatives having inhibitory activity against carboxypeptidase B
AU3764693A (en) Phenol and pyridinol derivatives as lusitropic agents
JPS63239290A (ja) 新規の二環式ジホスホネート化合物、医薬組成物、および異常なカルシウムおよびホスフェート代謝の治療法
JPH07285976A (ja) ジホスホン酸化合物
JP2007517837A5 (enrdf_load_stackoverflow)
EP0996439B1 (en) Beta-alkoxyacrylates against malaria
JPH10500977A (ja) ピリジルビスホスホン酸エステルよりなる治療用活性薬剤
CN105517996A (zh) 治疗活性化合物及其使用方法
EP0723969A1 (de) Phosphonocarbonsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
NL8403083A (nl) 1,2-dithiolaanderivaten, werkwijzen voor hun bereiding, farmaceutische preparaten die ze bevatten en hun toepassing.
JPH0580452B2 (enrdf_load_stackoverflow)