AU3595799A - Substituted guanidines and diaminonitroethenes, their preparation and use - Google Patents

Substituted guanidines and diaminonitroethenes, their preparation and use Download PDF

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Publication number
AU3595799A
AU3595799A AU35957/99A AU3595799A AU3595799A AU 3595799 A AU3595799 A AU 3595799A AU 35957/99 A AU35957/99 A AU 35957/99A AU 3595799 A AU3595799 A AU 3595799A AU 3595799 A AU3595799 A AU 3595799A
Authority
AU
Australia
Prior art keywords
cyano
trifluoromethyl
guanidine
dichlorophenyl
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU35957/99A
Other languages
English (en)
Inventor
John Bondo Hansen
John Patrick Mogensen
Tina Moller Tagmose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU3595799A publication Critical patent/AU3595799A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU35957/99A 1998-05-11 1999-05-06 Substituted guanidines and diaminonitroethenes, their preparation and use Abandoned AU3595799A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK63498 1998-05-11
DK634/98 1998-05-11
PCT/DK1999/000251 WO1999058497A1 (fr) 1998-05-11 1999-05-06 Guanidines et diaminonitroethenes substituees, preparation et applications

Publications (1)

Publication Number Publication Date
AU3595799A true AU3595799A (en) 1999-11-29

Family

ID=8095813

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35957/99A Abandoned AU3595799A (en) 1998-05-11 1999-05-06 Substituted guanidines and diaminonitroethenes, their preparation and use

Country Status (5)

Country Link
EP (1) EP1077933A1 (fr)
JP (1) JP2002514621A (fr)
AU (1) AU3595799A (fr)
CA (1) CA2331299A1 (fr)
WO (1) WO1999058497A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268284B1 (en) 1998-10-07 2001-07-31 Tokyo Electron Limited In situ titanium aluminide deposit in high aspect ratio features
CN100439332C (zh) * 2000-08-21 2008-12-03 株式会社太平洋 硫脲衍生物以及包含该衍生物的药物组合物
EP1782812A1 (fr) * 2004-06-23 2007-05-09 Neurotec Pharma, S.L. Composes destines au traitement de l'inflammation du systeme nerveux central
EP3932932A1 (fr) 2013-03-13 2022-01-05 Sage Therapeutics, Inc. Stéroïdes neuroactifs et leurs procédés d'utilisation
CA2991313C (fr) 2015-07-06 2023-12-19 Sage Therapeutics, Inc. Oxysterols et leurs procedes d'utilisation
AU2017240157B2 (en) 2016-04-01 2022-10-20 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
MD3481846T2 (ro) 2016-07-07 2021-11-30 Sage Therapeutics Inc 24-Hidroxisteroli 11-substituiți pentru utilizare în tratamentul stărilor legate de NMDA
CA3038900A1 (fr) 2016-09-30 2018-04-05 Sage Therapeutics, Inc. Oxysterols substitues en c7 et procedes en tant que modulateurs nmda
AU2017345399B2 (en) 2016-10-18 2022-02-24 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
NZ752732A (en) 2016-10-18 2024-08-30 Sage Therapeutics Inc Oxysterols and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3232462A1 (de) * 1982-09-01 1984-03-01 Bayer Ag, 5090 Leverkusen 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0254553B1 (fr) * 1986-07-23 1993-01-13 Hitachi Chemical Company, Ltd. Médium d'enregistrement optique
EP0310545A3 (fr) * 1987-09-02 1989-07-26 Ciba-Geigy Ag Cyanoguanidines comme durcisseur de résines epoxydes
JP2749639B2 (ja) * 1989-06-28 1998-05-13 鐘紡株式会社 シアノグアニジン誘導体
JPH0558985A (ja) * 1991-08-29 1993-03-09 Kanebo Ltd シアノグアニジン誘導体の製造法
DK41193D0 (da) * 1993-04-07 1993-04-07 Neurosearch As Ionkanalaabnere
JP3270789B2 (ja) * 1994-01-31 2002-04-02 カネボウ株式会社 養毛剤

Also Published As

Publication number Publication date
WO1999058497A1 (fr) 1999-11-18
JP2002514621A (ja) 2002-05-21
EP1077933A1 (fr) 2001-02-28
CA2331299A1 (fr) 1999-11-18

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period