AU2098983A - Pharmaceutical 6alpha-methylcarticoids - Google Patents

Pharmaceutical 6alpha-methylcarticoids

Info

Publication number
AU2098983A
AU2098983A AU20989/83A AU2098983A AU2098983A AU 2098983 A AU2098983 A AU 2098983A AU 20989/83 A AU20989/83 A AU 20989/83A AU 2098983 A AU2098983 A AU 2098983A AU 2098983 A AU2098983 A AU 2098983A
Authority
AU
Australia
Prior art keywords
methylcarticoids
6alpha
pharmaceutical
acyloxy
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU20989/83A
Other languages
English (en)
Inventor
Klaus Annen
Henry Laurent
Hans Wendt
Rudolf Wiechert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU2098983A publication Critical patent/AU2098983A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Seasonings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Manufacture Of Tobacco Products (AREA)
AU20989/83A 1982-11-22 1983-11-04 Pharmaceutical 6alpha-methylcarticoids Abandoned AU2098983A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823243482 DE3243482A1 (de) 1982-11-22 1982-11-22 Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE32434820 1982-11-22

Publications (1)

Publication Number Publication Date
AU2098983A true AU2098983A (en) 1984-05-31

Family

ID=6178924

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20989/83A Abandoned AU2098983A (en) 1982-11-22 1983-11-04 Pharmaceutical 6alpha-methylcarticoids

Country Status (22)

Country Link
US (1) US4645763A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0110041B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59106500A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE28651T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2098983A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (2) BG42677A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1303607C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS248712B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD219200A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3243482A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK159686C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8405421A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2130587A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR79725B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU190746B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE56281B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL70160A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO157454C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (3) PL141686B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT77408B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (2) RO89343A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA838720B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60161914A (ja) * 1984-02-02 1985-08-23 Green Cross Corp:The ステロイド脂肪酸エステル含有直腸投与製剤
JPS61274795A (ja) * 1985-05-30 1986-12-04 Toshiba Corp 曝気槽の溶存酸素濃度制御装置
US4968822A (en) * 1987-12-11 1990-11-06 Taisho Pharmaceutical Co., Ltd. 21-alkoxysteroid compounds
JPH05501115A (ja) * 1990-03-27 1993-03-04 シェリング・コーポレーション 9α―ヒドロキシ ステロイドの脱水法
DE4333920A1 (de) * 1993-10-05 1995-04-13 Hoechst Ag Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
ITMI20011762A1 (it) 2001-08-10 2003-02-10 Cosmo Spa Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione
ITMI20071616A1 (it) 2007-08-03 2009-02-04 Cosmo Spa Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
JP5780521B2 (ja) * 2008-05-28 2015-09-16 リベラジェン・バイオファーマ・インコーポレイテッドReveraGen BioPharma,Inc. 疾患を治療するための、NF−κBの非ホルモン性ステロイド調節因子
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053832A (en) * 1957-04-29 1962-09-11 Schering Corp Alkylated cortical steroids
GB921533A (en) * 1958-07-12 1963-03-20 Syntex Sa Cyclopentanophenanthrene derivatives and process for the production thereof
GB1047518A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
US4243586A (en) * 1980-01-18 1981-01-06 E. R. Squibb & Sons, Inc. Steroidal-17-spiro-dihydrofuranones
US4336200A (en) * 1980-01-31 1982-06-22 The Upjohn Company 17α-Acyloxy-5β-corticoids
US4318853A (en) * 1980-01-31 1982-03-09 The Upjohn Company 9β,11β-Epoxy-5β-corticoids
ATE12237T1 (de) * 1980-12-23 1985-04-15 Schering Ag Neue 6-alpha-methylhydrocortison-derivate, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
DK533783D0 (da) 1983-11-22
US4645763A (en) 1987-02-24
PL138796B1 (en) 1986-11-29
JPH0415799B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-03-19
IE832708L (en) 1984-05-22
JPS59106500A (ja) 1984-06-20
ES526446A0 (es) 1984-06-16
NO157454C (no) 1988-03-23
DK533783A (da) 1984-05-23
GB2130587A (en) 1984-06-06
ATE28651T1 (de) 1987-08-15
DE3243482A1 (de) 1984-05-24
RO89343A (ro) 1986-03-15
EP0110041B1 (de) 1987-07-29
DK159686B (da) 1990-11-19
CA1303607C (en) 1992-06-16
PL244685A1 (en) 1985-04-24
PT77408A (de) 1983-10-01
IE56281B1 (en) 1991-06-05
NO834265L (no) 1984-05-23
DE3372776D1 (en) 1987-09-03
PL141686B1 (en) 1987-08-31
RO93593A (ro) 1987-12-31
EP0110041A1 (de) 1984-06-13
HU190746B (en) 1986-10-28
BG42677A3 (en) 1988-01-15
ZA838720B (en) 1984-07-25
ES8405421A1 (es) 1984-06-16
GB8327736D0 (en) 1983-11-16
IL70160A0 (en) 1984-02-29
NO157454B (no) 1987-12-14
BG43867A3 (en) 1988-08-15
DD219200A5 (de) 1985-02-27
PT77408B (de) 1986-02-27
IL70160A (en) 1988-03-31
GR79725B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-10-31
PL250734A1 (en) 1985-07-30
RO93593B (ro) 1988-01-01
CS248712B2 (en) 1987-02-12
DK159686C (da) 1991-04-15
PL250735A1 (en) 1985-07-30

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