AU2023219232A1 - Combination of compounds for treating vascular diseases comprising pde5 inhibitor, arginine and n-acetylcysteine - Google Patents
Combination of compounds for treating vascular diseases comprising pde5 inhibitor, arginine and n-acetylcysteine Download PDFInfo
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- AU2023219232A1 AU2023219232A1 AU2023219232A AU2023219232A AU2023219232A1 AU 2023219232 A1 AU2023219232 A1 AU 2023219232A1 AU 2023219232 A AU2023219232 A AU 2023219232A AU 2023219232 A AU2023219232 A AU 2023219232A AU 2023219232 A1 AU2023219232 A1 AU 2023219232A1
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- pharmaceutical combination
- arginine
- sildenafil
- pde5 inhibitor
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- A—HUMAN NECESSITIES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
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- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
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- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW111104639A TWI859506B (zh) | 2022-02-09 | 2022-02-09 | 化合物組合用於製作血管疾病治療藥的用途 |
| TW111104639 | 2022-02-09 | ||
| PCT/GB2023/050296 WO2023152500A1 (en) | 2022-02-09 | 2023-02-09 | Combination of compounds for treating vascular diseases comprising pde5 inhibitor, arginine and n-acetylcysteine |
Publications (1)
| Publication Number | Publication Date |
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| AU2023219232A1 true AU2023219232A1 (en) | 2024-07-25 |
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| AU2023219232A Pending AU2023219232A1 (en) | 2022-02-09 | 2023-02-09 | Combination of compounds for treating vascular diseases comprising pde5 inhibitor, arginine and n-acetylcysteine |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250134892A1 (https=) |
| EP (1) | EP4475833A1 (https=) |
| JP (1) | JP2025504219A (https=) |
| KR (1) | KR20240146018A (https=) |
| CN (1) | CN116808224A (https=) |
| AU (1) | AU2023219232A1 (https=) |
| TW (1) | TWI859506B (https=) |
| WO (1) | WO2023152500A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025046207A1 (en) * | 2023-08-31 | 2025-03-06 | Future Pharmtech Inc. | New use of a pde 5 inhibitor combination in promoting neurite outgrowth |
| TWI879058B (zh) * | 2023-08-31 | 2025-04-01 | 未來新藥股份有限公司 | Pde5抑制劑組合於促進神經突生長之新穎用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AU4699299A (en) | 1998-06-26 | 2000-01-17 | Nutracorp Scientific, Inc. | Promoting nitric oxide and cyclic gmp activity |
| IL132460A0 (en) * | 1999-10-19 | 2001-03-19 | Laniado Shlomo | Sildenafil preparation |
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2022
- 2022-02-09 TW TW111104639A patent/TWI859506B/zh active
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2023
- 2023-02-09 AU AU2023219232A patent/AU2023219232A1/en active Pending
- 2023-02-09 CN CN202310100652.1A patent/CN116808224A/zh active Pending
- 2023-02-09 KR KR1020247028842A patent/KR20240146018A/ko active Pending
- 2023-02-09 US US18/836,532 patent/US20250134892A1/en active Pending
- 2023-02-09 EP EP23706081.9A patent/EP4475833A1/en active Pending
- 2023-02-09 WO PCT/GB2023/050296 patent/WO2023152500A1/en not_active Ceased
- 2023-02-09 JP JP2024547249A patent/JP2025504219A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN116808224A (zh) | 2023-09-29 |
| JP2025504219A (ja) | 2025-02-06 |
| US20250134892A1 (en) | 2025-05-01 |
| TW202332450A (zh) | 2023-08-16 |
| WO2023152500A1 (en) | 2023-08-17 |
| EP4475833A1 (en) | 2024-12-18 |
| KR20240146018A (ko) | 2024-10-07 |
| TWI859506B (zh) | 2024-10-21 |
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