AU2020343325A1 - Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids - Google Patents

Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids Download PDF

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Publication number
AU2020343325A1
AU2020343325A1 AU2020343325A AU2020343325A AU2020343325A1 AU 2020343325 A1 AU2020343325 A1 AU 2020343325A1 AU 2020343325 A AU2020343325 A AU 2020343325A AU 2020343325 A AU2020343325 A AU 2020343325A AU 2020343325 A1 AU2020343325 A1 AU 2020343325A1
Authority
AU
Australia
Prior art keywords
formula
compound
reacting
heptane
hmbi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2020343325A
Other languages
English (en)
Inventor
Shengshu HUANG
Ye Lao
Fangyi LI
Filip Nuyens
Jatuporn Salaklang
Zhuo TANG
Li Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kemin Industries Inc
Original Assignee
Kemin Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemin Industries Inc filed Critical Kemin Industries Inc
Publication of AU2020343325A1 publication Critical patent/AU2020343325A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A23K50/15—Feeding-stuffs specially adapted for particular animals for ruminants containing substances which are metabolically converted to proteins, e.g. ammonium salts or urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C07C319/30—Separation; Purification from the by-products of refining mineral oils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2020343325A 2019-09-06 2020-09-03 Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids Abandoned AU2020343325A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019104692 2019-09-06
CNPCT/CN2019/104692 2019-09-06
PCT/US2020/049222 WO2021046234A1 (en) 2019-09-06 2020-09-03 Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids

Publications (1)

Publication Number Publication Date
AU2020343325A1 true AU2020343325A1 (en) 2022-03-03

Family

ID=74852116

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020343325A Abandoned AU2020343325A1 (en) 2019-09-06 2020-09-03 Processes for the preparation of alpha-hydroxy esters by esterification of alpha-hydroxy acids

Country Status (11)

Country Link
US (2) US20220332681A1 (cg-RX-API-DMAC7.html)
EP (1) EP4025561A4 (cg-RX-API-DMAC7.html)
JP (2) JP7765382B2 (cg-RX-API-DMAC7.html)
KR (1) KR20220057525A (cg-RX-API-DMAC7.html)
CN (2) CN121318803A (cg-RX-API-DMAC7.html)
AU (1) AU2020343325A1 (cg-RX-API-DMAC7.html)
CA (1) CA3150773A1 (cg-RX-API-DMAC7.html)
CL (3) CL2022000516A1 (cg-RX-API-DMAC7.html)
CO (1) CO2022003063A2 (cg-RX-API-DMAC7.html)
MX (1) MX2022002512A (cg-RX-API-DMAC7.html)
WO (1) WO2021046234A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7846005B2 (ja) * 2019-11-22 2026-04-14 ケミン、インダストリーズ、インコーポレーテッド グリニャールカップリング反応及びチオール化反応によるα－ヒドロキシエステルの製造方法
KR102829625B1 (ko) * 2022-03-29 2025-07-04 한국바이오켐제약 주식회사 페노피브릭산의 정제방법 및 이에 의해 제조된 페노피브레이트

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874877A (en) * 1988-04-19 1989-10-17 Pfizer Inc. Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤
FR2785773B1 (fr) * 1998-11-13 2001-04-20 Rhone Poulenc Nutrition Animal Utilisation d'esters de methionine en nutrition animale
FR2791673B1 (fr) * 1999-04-02 2001-06-08 Rhone Poulenc Animal Nutrition Procede de preparation des esters de l'acide hydroxymethylthiobutyrique
WO2001058864A1 (en) * 2000-02-07 2001-08-16 Rhone-Poulenc Animal Nutrition Process for the preparation of 2-hydroxy-4-methylthio butyric acid esters
WO2003070684A1 (en) * 2002-02-19 2003-08-28 Amato Pharmaceutical Products, Ltd. Process for producing chain oligolactic acid ester
US20080319043A1 (en) * 2005-05-03 2008-12-25 Mohammad Salman 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists
CN101489998B (zh) * 2006-07-21 2013-01-02 住友化学株式会社 生产2-羟基-4-(甲硫基)丁酸或丁酸酯化合物及其中间体的方法
CN102093271A (zh) * 2011-01-25 2011-06-15 张维军 2-羟基-4-甲硫基丁酸烷基酯的制备方法
RU2019131408A (ru) * 2014-11-28 2019-10-29 Хальдор Топсёэ А/С Способ получения сложных эфиров молочной кислоты из сахаров
MY198309A (en) * 2016-06-24 2023-08-22 Novus Int Inc Hydroxy methionine analog formulations suibtable for specialty chemical applications
CN111825584B (zh) * 2020-07-30 2022-04-12 北京福元医药股份有限公司沧州分公司 一种消旋羟蛋氨酸钙的制备方法

Also Published As

Publication number Publication date
JP2022546018A (ja) 2022-11-02
MX2022002512A (es) 2022-08-22
CN121318803A (zh) 2026-01-13
WO2021046234A1 (en) 2021-03-11
EP4025561A1 (en) 2022-07-13
CL2022000516A1 (es) 2022-10-07
JP2025041771A (ja) 2025-03-26
CL2024002285A1 (es) 2024-12-27
BR112022003547A2 (pt) 2022-05-17
JP7765382B2 (ja) 2025-11-06
US20220332681A1 (en) 2022-10-20
CL2024002284A1 (es) 2024-12-27
CN114341107A (zh) 2022-04-12
CO2022003063A2 (es) 2022-04-19
CA3150773A1 (en) 2021-03-11
KR20220057525A (ko) 2022-05-09
US20260001837A1 (en) 2026-01-01
EP4025561A4 (en) 2024-01-31

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