AU2020262416A1 - Fully-human post-translationally modified antibody therapeutics - Google Patents

Fully-human post-translationally modified antibody therapeutics Download PDF

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Publication number
AU2020262416A1
AU2020262416A1 AU2020262416A AU2020262416A AU2020262416A1 AU 2020262416 A1 AU2020262416 A1 AU 2020262416A1 AU 2020262416 A AU2020262416 A AU 2020262416A AU 2020262416 A AU2020262416 A AU 2020262416A AU 2020262416 A1 AU2020262416 A1 AU 2020262416A1
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Australia
Prior art keywords
seq
mab
amino acid
acid sequence
capsid
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Abandoned
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AU2020262416A
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English (en)
Inventor
Joseph Bruder
Olivier Danos
Sherri Van Everen
Franz GERNER
Justin GLENN
Ye Liu
Devin MCDOUGALD
Chunping Qiao
Xu Wang
Zuchun WU
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Regenxbio Inc
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Regenxbio Inc
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Publication of AU2020262416A1 publication Critical patent/AU2020262416A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Virology (AREA)
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AU2020262416A 2019-04-24 2020-04-24 Fully-human post-translationally modified antibody therapeutics Abandoned AU2020262416A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962838165P 2019-04-24 2019-04-24
US62/838,165 2019-04-24
US202062967472P 2020-01-29 2020-01-29
US62/967,472 2020-01-29
PCT/US2020/029802 WO2020219868A1 (en) 2019-04-24 2020-04-24 Fully-human post-translationally modified antibody therapeutics

Publications (1)

Publication Number Publication Date
AU2020262416A1 true AU2020262416A1 (en) 2021-12-16

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ID=70861534

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020262416A Abandoned AU2020262416A1 (en) 2019-04-24 2020-04-24 Fully-human post-translationally modified antibody therapeutics

Country Status (13)

Country Link
US (1) US20220195462A1 (https=)
EP (1) EP3959323A1 (https=)
JP (2) JP7672344B2 (https=)
KR (1) KR20220012231A (https=)
CN (1) CN114144197A (https=)
AU (1) AU2020262416A1 (https=)
BR (1) BR112021021156A2 (https=)
CA (1) CA3137284A1 (https=)
IL (1) IL287414A (https=)
MX (1) MX2021012867A (https=)
SG (1) SG11202111414RA (https=)
TW (1) TW202106708A (https=)
WO (1) WO2020219868A1 (https=)

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