AU2020253429A1 - Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells - Google Patents

Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells Download PDF

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AU2020253429A1
AU2020253429A1 AU2020253429A AU2020253429A AU2020253429A1 AU 2020253429 A1 AU2020253429 A1 AU 2020253429A1 AU 2020253429 A AU2020253429 A AU 2020253429A AU 2020253429 A AU2020253429 A AU 2020253429A AU 2020253429 A1 AU2020253429 A1 AU 2020253429A1
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cells
thymic epithelial
pharyngeal
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Nichole DANZL
Rafael GRAS PENA
Mohsen KHOSRAVI-MAHARLOOEI
Megan Sykes
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Columbia University in the City of New York
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Columbia University in the City of New York
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AU2020253429A 2019-04-01 2020-03-31 Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells Pending AU2020253429A1 (en)

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US201962827383P 2019-04-01 2019-04-01
US62/827,383 2019-04-01
PCT/US2020/025955 WO2020205859A1 (en) 2019-04-01 2020-03-31 Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells

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US (1) US20220127569A1 (enExample)
EP (1) EP3947639A4 (enExample)
JP (2) JP7740706B2 (enExample)
KR (1) KR20210146297A (enExample)
CN (2) CN113646423B (enExample)
AU (1) AU2020253429A1 (enExample)
CA (1) CA3135377A1 (enExample)
IL (1) IL286936A (enExample)
MX (1) MX2021012041A (enExample)
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Publication number Priority date Publication date Assignee Title
KR20230004690A (ko) * 2020-04-28 2023-01-06 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 시험관 내에서 흉선 세포를 생성하는 방법
US20240076618A1 (en) * 2021-01-15 2024-03-07 The Board Of Trustees Of The Leland Stanford Junior University Generation of induced human thymic epithelial cells and its application in cell-based immunotherapies
CN113215081B (zh) * 2021-06-01 2023-04-14 华中科技大学同济医学院附属同济医院 诱导干细胞分化为甲状旁腺细胞的方法及其组合物
KR20240075885A (ko) * 2021-10-15 2024-05-29 타이뮨 테라퓨틱스, 인코포레이티드 가슴샘 세포 및 제조 방법
EP4293110A1 (en) 2022-06-17 2023-12-20 Nantes Université Process for obtaining functional lymphocytes cells
WO2025136749A1 (en) * 2023-12-19 2025-06-26 The Board Of Trustees Of The Leland Stanford Junior University Thymic epithelial cells and methods of producing and using the same
CN119614476A (zh) * 2024-11-13 2025-03-14 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） 胸腺类器官的构建方法和应用

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JP2004516834A (ja) * 2000-12-22 2004-06-10 ユニヴァーシティー オブ エディンバラ 胸腺上皮前駆細胞およびその使用
WO2010143529A1 (ja) 2009-06-09 2010-12-16 国立大学法人名古屋大学 多能性幹細胞を胸腺上皮へ分化誘導する方法
JP2013524836A (ja) * 2010-04-25 2013-06-20 マウント・シナイ・スクール・オブ・メディスン 多能性細胞からの前部前腸内胚葉の生成
CN102732479B (zh) * 2011-03-31 2014-08-27 北京大学 胸腺上皮前体细胞的制备方法及其专用培养基
WO2014058274A1 (ko) * 2012-10-12 2014-04-17 서강대학교 산학협력단 미분화 인간 유도만능줄기세포의 선택적 세포사멸 유도를 통한 테라토마 형성 억제 방법
EP2961829A4 (en) * 2013-02-27 2016-08-17 Univ California GENERATION OF THYME PEPPER THERAPEUTIC CELLS IN VITRO
JP7372910B2 (ja) 2017-09-20 2023-11-01 アメリカ合衆国 ヒト多能性幹細胞由来の胸腺オルガノイドのインビトロ生成
EP3959304A4 (en) * 2019-04-26 2023-01-25 The Regents Of The University Of Colorado, A Body Corporate GENERATION OF FUNCTIONAL AND PATIENT-SPECIFIC THYMUS TISSUE IN VIVO FROM INDUCED PLURIPOTENTS STEM CELLS
US20230002727A1 (en) * 2019-11-25 2023-01-05 Allegheny Singer Research Institute Thymus organoids bioengineered from human pluripotent stem cells

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JP7740706B2 (ja) 2025-09-17
KR20210146297A (ko) 2021-12-03
US20220127569A1 (en) 2022-04-28
CA3135377A1 (en) 2020-10-08
IL286936A (en) 2021-10-31
WO2020205859A1 (en) 2020-10-08
JP2022527338A (ja) 2022-06-01
CN113646423B (zh) 2024-10-01
JP2024153768A (ja) 2024-10-29
EP3947639A4 (en) 2023-01-25
SG11202109279PA (en) 2021-09-29
CN119351306A (zh) 2025-01-24
EP3947639A1 (en) 2022-02-09
CN113646423A (zh) 2021-11-12

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