JP7740706B2 - 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 - Google Patents

多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法

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JP7740706B2
JP7740706B2 JP2021558816A JP2021558816A JP7740706B2 JP 7740706 B2 JP7740706 B2 JP 7740706B2 JP 2021558816 A JP2021558816 A JP 2021558816A JP 2021558816 A JP2021558816 A JP 2021558816A JP 7740706 B2 JP7740706 B2 JP 7740706B2
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cells
human
pharyngeal
thymic
endoderm
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JP2022527338A (ja
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ペナ，ラファエル グラス
サイクス，メーガン
ダンツル，ニコル
コスラヴィ‐マハールーイ，モーゼン
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Columbia University in the City of New York
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JP2021558816A 2019-04-01 2020-03-31 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 Active JP7740706B2 (ja)

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US201962827383P 2019-04-01 2019-04-01
US62/827,383 2019-04-01
PCT/US2020/025955 WO2020205859A1 (en) 2019-04-01 2020-03-31 Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells

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JP2024121246A Pending JP2024153768A (ja) 2019-04-01 2024-07-26 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法

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AU2021262770A1 (en) * 2020-04-28 2022-11-17 The Regents Of The University Of California Methods for generating thymic cells in vitro
EP4277977A4 (en) * 2021-01-15 2025-02-12 The Board of Trustees of the Leland Stanford Junior University PRODUCTION OF INDUCED HUMAN THYMIC EPITHELIAL CELLS AND THEIR APPLICATION IN CELL-BASED IMMUNOTHERAPIES
CN113215081B (zh) * 2021-06-01 2023-04-14 华中科技大学同济医学院附属同济医院 诱导干细胞分化为甲状旁腺细胞的方法及其组合物
EP4416267A4 (en) * 2021-10-15 2025-10-08 Thymmune Therapeutics Inc THYMIC CELLS AND THEIR PROCESSES OF MANUFACTURE
EP4293110A1 (en) 2022-06-17 2023-12-20 Nantes Université Process for obtaining functional lymphocytes cells
WO2025136749A1 (en) * 2023-12-19 2025-06-26 The Board Of Trustees Of The Leland Stanford Junior University Thymic epithelial cells and methods of producing and using the same
CN119614476A (zh) * 2024-11-13 2025-03-14 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） 胸腺类器官的构建方法和应用

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JP2004516834A (ja) 2000-12-22 2004-06-10 ユニヴァーシティー オブ エディンバラ 胸腺上皮前駆細胞およびその使用
JP2013524836A (ja) 2010-04-25 2013-06-20 マウント・シナイ・スクール・オブ・メディスン 多能性細胞からの前部前腸内胚葉の生成

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JPWO2010143529A1 (ja) * 2009-06-09 2012-11-22 国立大学法人名古屋大学 多能性幹細胞を胸腺上皮へ分化誘導する方法
CN102732479B (zh) * 2011-03-31 2014-08-27 北京大学 胸腺上皮前体细胞的制备方法及其专用培养基
US9657273B2 (en) * 2012-10-12 2017-05-23 Industry-University Cooperation Foundation Sogang University Method for suppressing teratoma formation via selective cell death induction in undifferentiated human-induced pluripotent stem cells
CA2902857C (en) 2013-02-27 2022-11-29 The Regents Of The University Of California Generation of thymic epithelial progenitor cells in vitro
EP3684920A1 (en) 2017-09-20 2020-07-29 The U.S.A. as represented by the Secretary, Department of Health and Human Services In vitro generation of thymic organoid from human pluripotent stem cells
KR20220004126A (ko) * 2019-04-26 2022-01-11 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 유도 다능성 줄기 세포로부터 생체내에서 기능적이고 환자-특이적인 흉선 조직의 생성
WO2021108514A1 (en) * 2019-11-25 2021-06-03 Allegheny Singer Research Institute Thymus organoids bioengineered form human pluripotent stem cells

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JP2004516834A (ja) 2000-12-22 2004-06-10 ユニヴァーシティー オブ エディンバラ 胸腺上皮前駆細胞およびその使用
JP2013524836A (ja) 2010-04-25 2013-06-20 マウント・シナイ・スクール・オブ・メディスン 多能性細胞からの前部前腸内胚葉の生成

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US20220127569A1 (en) 2022-04-28
MX2021012041A (es) 2021-11-03
CA3135377A1 (en) 2020-10-08
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JP2022527338A (ja) 2022-06-01
AU2020253429A1 (en) 2021-09-09
EP3947639A4 (en) 2023-01-25
JP2024153768A (ja) 2024-10-29
CN113646423A (zh) 2021-11-12
SG11202109279PA (en) 2021-09-29
WO2020205859A1 (en) 2020-10-08
CN113646423B (zh) 2024-10-01

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