AU2019403220A1 - Methods and compositions to reduce nonspecific amplification in isothermal amplification reactions - Google Patents
Methods and compositions to reduce nonspecific amplification in isothermal amplification reactions Download PDFInfo
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- AU2019403220A1 AU2019403220A1 AU2019403220A AU2019403220A AU2019403220A1 AU 2019403220 A1 AU2019403220 A1 AU 2019403220A1 AU 2019403220 A AU2019403220 A AU 2019403220A AU 2019403220 A AU2019403220 A AU 2019403220A AU 2019403220 A1 AU2019403220 A1 AU 2019403220A1
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- nucleic acid
- seq
- inhibitor oligonucleotide
- nucleotide sequence
- aqueous solution
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
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| US201862782610P | 2018-12-20 | 2018-12-20 | |
| US62/782,610 | 2018-12-20 | ||
| PCT/US2019/067134 WO2020132042A1 (en) | 2018-12-20 | 2019-12-18 | Methods and compositions to reduce nonspecific amplification in isothermal amplification reactions |
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| US10196678B2 (en) | 2014-10-06 | 2019-02-05 | ALVEO Technologies Inc. | System and method for detection of nucleic acids |
| CN109996888A (zh) | 2016-09-23 | 2019-07-09 | 阿尔韦奥科技公司 | 用于检测分析物的方法和组合物 |
| EP3899022A4 (en) | 2018-12-20 | 2023-03-01 | Alveo Technologies Inc. | PORTABLE IMPEDANCE-BASED DIAGNOSTIC TEST SYSTEM FOR DETECTING ANALYTES |
| JP2023536962A (ja) * | 2020-08-06 | 2023-08-30 | エフ． ホフマン－ラ ロシュ アーゲー | 重症急性呼吸器症候群コロナウイルス２（ｓａｒｓ－２）、インフルエンザａ及びインフルエンザｂの検出のための組成物及び方法 |
| US12472492B2 (en) | 2020-08-14 | 2025-11-18 | Alveo Technologies, Inc. | Systems and methods of sample depositing and testing |
| CN119948173A (zh) * | 2022-09-07 | 2025-05-06 | 贝克顿迪金森公司 | 用于改进检测特异性的修饰的分子信标 |
| PL442248A1 (pl) * | 2022-09-12 | 2024-03-18 | Genomtec Spółka Akcyjna | Zestaw starterów, skład mieszaniny reakcyjnej oraz metoda wykrywania ludzkiego syncytialnego wirusa oddechowego (ang. Human Respiratory Syncital Virus) typ A i typ B (RSVA) i (RSVB) |
| WO2024191684A1 (en) * | 2023-03-10 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Detection of hepatitis c virus ribonucleic acid from whole blood using reverse transcription loop-mediated isothermal amplification |
| WO2026006021A2 (en) | 2024-06-25 | 2026-01-02 | Alveo Technologies, Inc. | Systems and methods of sample depositing and testing |
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| US20070212704A1 (en) * | 2005-10-03 | 2007-09-13 | Applera Corporation | Compositions, methods, and kits for amplifying nucleic acids |
| US8097414B2 (en) * | 2005-11-25 | 2012-01-17 | K. K. Dnaform | Method for detecting and amplifying nucleic acid |
| WO2007074894A1 (ja) * | 2005-12-28 | 2007-07-05 | School Corporation, Azabu Veterinary Medicine Educational Institution | 標的配列の特異的高感度増幅法 |
| CN103459612A (zh) * | 2010-12-03 | 2013-12-18 | 布兰代斯大学 | 用于检测野生型群体中的核酸突变体的方法和试剂盒 |
| SG193315A1 (en) * | 2011-03-04 | 2013-10-30 | Kaneka Corp | Nucleic acid detection method, and device and kit for use in same |
| EP3058100A4 (en) * | 2013-10-18 | 2017-04-19 | California Institute of Technology | Enhanced nucleic acid identification and detection |
| CA2971200A1 (en) * | 2014-12-19 | 2016-06-23 | Brandeis University | Mispriming prevention reagents |
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