AU2019294603B2 - Methods of treating CLRN1-associated hearing loss and/or vision loss - Google Patents

Methods of treating CLRN1-associated hearing loss and/or vision loss

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Publication number
AU2019294603B2
AU2019294603B2 AU2019294603A AU2019294603A AU2019294603B2 AU 2019294603 B2 AU2019294603 B2 AU 2019294603B2 AU 2019294603 A AU2019294603 A AU 2019294603A AU 2019294603 A AU2019294603 A AU 2019294603A AU 2019294603 B2 AU2019294603 B2 AU 2019294603B2
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amino acids
nucleotides
amino acid
acid substitutions
seq
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AU2019294603A1 (en
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Robert NG
Emmanuel J. Simons
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Akouos Inc
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Akouos Inc
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    • C12N15/86—Viral vectors
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
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    • C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal

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AU2019294603A 2018-06-25 2019-06-25 Methods of treating CLRN1-associated hearing loss and/or vision loss Active AU2019294603B2 (en)

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AU2026201371A AU2026201371A1 (en) 2018-06-25 2026-02-24 Methods of treating CLRN1-associated hearing loss and/or vision loss

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US201862689660P 2018-06-25 2018-06-25
US62/689,660 2018-06-25
PCT/US2019/039030 WO2020005974A1 (en) 2018-06-25 2019-06-25 Methods of treating clrn1-associated hearing loss and/or vision loss

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JP (3) JP2021529519A (enExample)
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CN (1) CN112639107B (enExample)
AU (2) AU2019294603B2 (enExample)
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US20230340038A1 (en) * 2020-09-14 2023-10-26 President And Fellows Of Harvard College Recombinant adeno associated virus (raav) encoding gjb2 and uses thereof
CN117157108A (zh) * 2020-12-29 2023-12-01 阿库斯股份有限公司 用于治疗clrn1相关听力损失和/或视力损失的组合物和方法
JP2024537796A (ja) * 2021-09-30 2024-10-16 アコーオス インコーポレイテッド 難聴を治療するための遺伝子療法送達組成物及び方法

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US20100160415A1 (en) * 2005-10-05 2010-06-24 Bayhill Therapeutics, Inc Compositions and methods for treatment of autoimmune disease
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WO2018039375A1 (en) * 2016-08-23 2018-03-01 Akouos, Inc. Compositions and methods for treating non-age-associated hearing impairment in a human subject

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JP2023153320A (ja) 2023-10-17
KR20260073466A (ko) 2026-05-21
CN112639107B (zh) 2025-03-04
CL2020003346A1 (es) 2021-05-14
AU2019294603A1 (en) 2021-01-14
CA3104330A1 (en) 2020-01-02
BR112020026606A2 (pt) 2021-04-06
CN112639107A (zh) 2021-04-09
WO2020005974A1 (en) 2020-01-02
KR20210057720A (ko) 2021-05-21
US20210277417A1 (en) 2021-09-09
EP3824090A1 (en) 2021-05-26
MX2020013628A (es) 2021-05-27
EP3824090A4 (en) 2022-06-01
JP2025156349A (ja) 2025-10-14
JP2021529519A (ja) 2021-11-04
AU2026201371A1 (en) 2026-03-19
IL279551A (en) 2021-01-31
SG11202012710WA (en) 2021-01-28
EA202190114A1 (ru) 2021-05-12

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