AU2019269671B2 - Protection of biologically active molecules during radiation sterilization - Google Patents

Protection of biologically active molecules during radiation sterilization Download PDF

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Publication number
AU2019269671B2
AU2019269671B2 AU2019269671A AU2019269671A AU2019269671B2 AU 2019269671 B2 AU2019269671 B2 AU 2019269671B2 AU 2019269671 A AU2019269671 A AU 2019269671A AU 2019269671 A AU2019269671 A AU 2019269671A AU 2019269671 B2 AU2019269671 B2 AU 2019269671B2
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AU
Australia
Prior art keywords
biologically active
radiation
activity
radioprotected
mixture
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Active
Application number
AU2019269671A
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English (en)
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AU2019269671A1 (en
Inventor
Nadia Patrice ALLEN
Jeff Boyle
Jenny Louise Howard
Paul Q. Hu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qiagen Sciences LLC
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Qiagen Sciences LLC
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Publication date
Application filed by Qiagen Sciences LLC filed Critical Qiagen Sciences LLC
Publication of AU2019269671A1 publication Critical patent/AU2019269671A1/en
Application granted granted Critical
Publication of AU2019269671B2 publication Critical patent/AU2019269671B2/en
Priority to AU2025202786A priority Critical patent/AU2025202786A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/087—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2019269671A 2018-05-18 2019-05-17 Protection of biologically active molecules during radiation sterilization Active AU2019269671B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025202786A AU2025202786A1 (en) 2018-05-18 2025-04-22 Protection of biologically active molecules during radiation sterilization

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862673671P 2018-05-18 2018-05-18
US62/673,671 2018-05-18
PCT/US2019/032885 WO2019222638A1 (en) 2018-05-18 2019-05-17 Protection of biologically active molecules during radiation sterilization

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025202786A Division AU2025202786A1 (en) 2018-05-18 2025-04-22 Protection of biologically active molecules during radiation sterilization

Publications (2)

Publication Number Publication Date
AU2019269671A1 AU2019269671A1 (en) 2020-10-22
AU2019269671B2 true AU2019269671B2 (en) 2025-01-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2019269671A Active AU2019269671B2 (en) 2018-05-18 2019-05-17 Protection of biologically active molecules during radiation sterilization
AU2025202786A Pending AU2025202786A1 (en) 2018-05-18 2025-04-22 Protection of biologically active molecules during radiation sterilization

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025202786A Pending AU2025202786A1 (en) 2018-05-18 2025-04-22 Protection of biologically active molecules during radiation sterilization

Country Status (9)

Country Link
US (1) US20210260225A1 (enExample)
EP (1) EP3793621A1 (enExample)
JP (2) JP7487184B2 (enExample)
KR (2) KR102774917B1 (enExample)
CN (1) CN112135641A (enExample)
AU (2) AU2019269671B2 (enExample)
MX (1) MX2020012237A (enExample)
SG (1) SG11202009795PA (enExample)
WO (1) WO2019222638A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114621467B (zh) * 2022-05-17 2022-07-29 天新福（北京）医疗器材股份有限公司 一种无菌自固化胶原蛋白修复凝胶及其制备方法
CN115611978B (zh) * 2022-11-21 2023-03-07 成都奇璞生物科技有限公司 一种辐照保护剂在制备胶原蛋白产品中的用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120107829A1 (en) * 2009-03-31 2012-05-03 Leukocare Ag Stabilizing compositions for immobilized biomolecules

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JP2649224B2 (ja) * 1987-02-25 1997-09-03 旭メディカル 株式会社 体液処理装置の滅菌方法および滅菌された体液処理装置
US6551794B1 (en) * 1995-11-09 2003-04-22 E. R. Squibb & Sons, Inc. Stable biotinylated biomolecule composition
JP4071283B2 (ja) * 1996-02-05 2008-04-02 旭化成クラレメディカル株式会社 滅菌保護剤及び滅菌方法
US5730933A (en) * 1996-04-16 1998-03-24 Depuy Orthopaedics, Inc. Radiation sterilization of biologically active compounds
EP1762251A1 (en) * 2000-03-23 2007-03-14 Clearant, Inc. Methods for sterilizing biological materials
US20030012687A1 (en) 2000-03-23 2003-01-16 Macphee Martin J. Methods of sterilizing biological materials
US20040086420A1 (en) 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) * 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US20030031584A1 (en) 2001-08-10 2003-02-13 Wilson Burgess Methods for sterilizing biological materials using dipeptide stabilizers
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) * 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
EP1415669A1 (en) * 2002-09-19 2004-05-06 Aventis Behring GmbH Process for sterilization of protein containing biological compositions
US20050069453A1 (en) 2003-09-29 2005-03-31 Ren-Yo Forng Methods for sterilizing preparations of urokinase
US20050175630A1 (en) * 2003-12-23 2005-08-11 Eyal Raz Immunogenic compositions and methods of use thereof
GB0626021D0 (en) * 2006-12-29 2007-02-07 Insense Ltd The stabilisation of proteins
US8304439B1 (en) * 2007-10-12 2012-11-06 Politechnika Lodzka Use of quaternary pyridinium salts as a therapeutic or preventing agent against ionizing radiation-induced damage
EP2236617A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
US8999720B2 (en) * 2011-11-17 2015-04-07 Medtronic Minimed, Inc. Aqueous radiation protecting formulations and methods for making and using them
CN108064229B (zh) * 2015-03-12 2021-12-28 三洋化成工业株式会社 蛋白质组合物的制造方法和蛋白质组合物
WO2016146573A1 (en) * 2015-03-13 2016-09-22 Repoceuticals Aps Melatonin for preventing and treating radiation cystitis
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WO2019166003A1 (zh) * 2018-03-02 2019-09-06 郑州大学 14-脱氧-11,12-脱氢-8,12-环氧或7,8-烯-穿心莲内酯及其15位取代衍生物和用途

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US20120107829A1 (en) * 2009-03-31 2012-05-03 Leukocare Ag Stabilizing compositions for immobilized biomolecules

Also Published As

Publication number Publication date
US20210260225A1 (en) 2021-08-26
CA3096717A1 (en) 2019-11-21
SG11202009795PA (en) 2020-12-30
KR20250030028A (ko) 2025-03-05
KR20210013553A (ko) 2021-02-04
JP2024073470A (ja) 2024-05-29
KR102774917B1 (ko) 2025-03-04
MX2020012237A (es) 2021-03-25
EP3793621A1 (en) 2021-03-24
BR112020021358A2 (pt) 2021-01-19
WO2019222638A1 (en) 2019-11-21
AU2019269671A1 (en) 2020-10-22
JP7487184B2 (ja) 2024-05-20
CN112135641A (zh) 2020-12-25
JP2021524362A (ja) 2021-09-13
AU2025202786A1 (en) 2025-05-08

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