AU2019264996A1 - Methods for prognosis and management of disease - Google Patents

Methods for prognosis and management of disease Download PDF

Info

Publication number
AU2019264996A1
AU2019264996A1 AU2019264996A AU2019264996A AU2019264996A1 AU 2019264996 A1 AU2019264996 A1 AU 2019264996A1 AU 2019264996 A AU2019264996 A AU 2019264996A AU 2019264996 A AU2019264996 A AU 2019264996A AU 2019264996 A1 AU2019264996 A1 AU 2019264996A1
Authority
AU
Australia
Prior art keywords
als
subject
biomarker
scd14
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2019264996A
Other languages
English (en)
Inventor
Stanley H. Appel
David R. Beers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Methodist Hospital
Original Assignee
Methodist Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methodist Hospital filed Critical Methodist Hospital
Publication of AU2019264996A1 publication Critical patent/AU2019264996A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2019264996A 2018-05-10 2019-05-10 Methods for prognosis and management of disease Abandoned AU2019264996A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862669915P 2018-05-10 2018-05-10
US62/669,915 2018-05-10
PCT/US2019/031858 WO2019217916A1 (en) 2018-05-10 2019-05-10 Methods for prognosis and management of disease

Publications (1)

Publication Number Publication Date
AU2019264996A1 true AU2019264996A1 (en) 2020-11-26

Family

ID=66655475

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019264996A Abandoned AU2019264996A1 (en) 2018-05-10 2019-05-10 Methods for prognosis and management of disease

Country Status (8)

Country Link
US (1) US20210231686A1 (https=)
EP (1) EP3791188A1 (https=)
JP (2) JP7371019B2 (https=)
KR (1) KR20210014109A (https=)
CN (1) CN112424608A (https=)
AU (1) AU2019264996A1 (https=)
IL (1) IL278616B2 (https=)
WO (1) WO2019217916A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL309046B2 (en) 2017-04-21 2025-03-01 Implicit Bioscience Ltd CD14 antagonist antibodies for the treatment of neurodegenerative diseases
CN113842449B (zh) * 2021-09-08 2024-02-23 乐卫东 枸杞糖肽在制备预防和/或治疗肌萎缩侧索硬化的药物中的应用
WO2025049671A1 (en) * 2023-08-30 2025-03-06 The Methodist Hospital Markers of amyotrophic lateral sclerosis survival and uses thereof
WO2025058005A1 (ja) * 2023-09-15 2025-03-20 国立大学法人徳島大学 筋萎縮性側索硬化症（ａｌｓ）と関連するバイオマーカー

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
ES2083152T3 (es) * 1990-11-30 1996-04-01 Monoclonetics Int Metodos para el diagnostico de dolores cronicos lumbares y cervicales.
US5820858A (en) 1993-05-28 1998-10-13 The Scripps Research Institute Methods and compositions for inhibiting CD14 mediated cell activation
CA2319828A1 (en) 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
AU2001255436A1 (en) 2000-04-17 2001-10-30 Transtech Pharma Protein expression system arrays and use in biological screening
GB0022978D0 (en) 2000-09-19 2000-11-01 Oxford Glycosciences Uk Ltd Detection of peptides
US20050130320A1 (en) 2000-11-09 2005-06-16 George Shaji. T. Method for identifying the proteome of cells using an antibody library microarray
AU2001290315A1 (en) 2000-11-22 2002-06-03 Mochida Pharmaceutical Co., Ltd. Anti-cd14 monoclonal antibody having effect of inhibiting cd14/tlr binding
US6800453B2 (en) 2001-01-23 2004-10-05 President And Fellows Of Harvard College Nucleic-acid programmable protein arrays
WO2003062444A2 (en) 2001-11-13 2003-07-31 Emory University Array systems and methods
JP2005510524A (ja) * 2001-11-16 2005-04-21 アルス・セラピー・デベロツプメント・フアンデーシヨン・インコーポレーテツド ポリアミン経路の調節による神経変性障害の治療
AU2003224674A1 (en) 2002-03-11 2003-09-29 Hk Pharmaceuticals, Inc. Compounds and methods for analyzing the proteome
WO2005020784A2 (en) * 2003-05-23 2005-03-10 Mount Sinai School Of Medicine Of New York University Surrogate cell gene expression signatures for evaluating the physical state of a subject
ES2406266T3 (es) * 2004-05-11 2013-06-06 Mochida Pharmaceutical Co., Ltd. Antígeno CD14 soluble novedoso
WO2010102412A1 (en) * 2009-03-11 2010-09-16 Augurex Life Sciences Corporation Compositions and methods for characterizing arthritic conditions
BR112012002333A2 (pt) * 2009-08-06 2017-07-18 Neuraltus Pharmaceuticals Inc método de reduzir os efeitos colaterais e método de potencializar o efeito de um imunomodulador administrado a um sujeito que dele necessita; métodos para tratar doença associada com excesso de ativação de monócitos para macrófagos ativados, diabetes tipo ii ou complicações relacionadas, doença associada com a migração de monócitos ou macrófagos ativados, doença associada a excesso de produção de scd14 e/ou scd163 por macrófagos ativados; composto de cloreto de sódio; composição farmacêutica; método para diagnosticar uma doença relacionada com macrófagos em um sujeito; e método para determinar a eficácia do tratamento com um agente oxidante para uma doença relacionada a macrófagos em um sujeito.
US8465727B2 (en) 2009-10-06 2013-06-18 University of Pittsburgh—of the Commonwealth System of Higher Education Biomarkers for the diagnosis of ALS
EP2501720A2 (en) * 2009-11-18 2012-09-26 Lascco SA Ifn inhibitors in the treatment of motoneuron diseases
WO2011111043A1 (en) * 2010-03-10 2011-09-15 Yeda Research And Development Co. Ltd Cellular blood markers for early diagnosis of als and for als progression
WO2012004276A2 (en) * 2010-07-06 2012-01-12 Fondazione Telethon Multiprotein biomarkers of amyotrophic lateral sclerosis in peripheral blood mononuclear cells, diagnostic methods and kits
US9506923B2 (en) * 2011-08-12 2016-11-29 Lsi Medience Corporation Method of diagnosing surgical site infections
US10184151B2 (en) * 2011-10-11 2019-01-22 The Brigham And Women's Hospital, Inc. Micrornas in neurodegenerative disorders
WO2014102333A1 (en) * 2012-12-28 2014-07-03 Mitsubishi Chemical Medience Corporation Use of scd14 or its fragments or derivatives for risk stratisfaction, diagnosis and prognosis
EP3142674A4 (en) * 2014-05-16 2018-01-17 Neuraltus Pharmaceuticals, Inc. Methods and compositions for treatment of macrophage-related disorders
WO2016083374A1 (en) * 2014-11-25 2016-06-02 F. Hoffmann-La Roche Ag Biomarkers of fast progression of chronic kidney disease
HK1250012A1 (zh) * 2015-04-02 2018-11-23 The Methodist Hospital System 基於多孔硅微粒的癌症疫苗及增强抗肿瘤免疫的方法
US10724095B2 (en) * 2015-12-16 2020-07-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Diagnostic markers of immunosenescence and methods for determining the susceptibility to nosocomial infections
WO2017147378A1 (en) * 2016-02-25 2017-08-31 The Trustees Of Columbia University In The City Of New York Systemic immune activation and biomarkers of nonceliac wheat/gluten sensitivity
IL309046B2 (en) 2017-04-21 2025-03-01 Implicit Bioscience Ltd CD14 antagonist antibodies for the treatment of neurodegenerative diseases
AU2024238511A1 (en) * 2023-03-21 2025-10-02 Coya Therapeutics, Inc. Biomarkers of amyotrophic lateral sclerosis and uses thereof

Also Published As

Publication number Publication date
IL278616B2 (en) 2025-02-01
IL278616A (https=) 2021-01-31
JP2021523375A (ja) 2021-09-02
US20210231686A1 (en) 2021-07-29
JP7371019B2 (ja) 2023-10-30
IL278616B1 (en) 2024-10-01
CN112424608A (zh) 2021-02-26
EP3791188A1 (en) 2021-03-17
WO2019217916A1 (en) 2019-11-14
JP2023181255A (ja) 2023-12-21
KR20210014109A (ko) 2021-02-08

Similar Documents

Publication Publication Date Title
US10877049B2 (en) Biomarkers for diagnosis and management of neuro-immunological diseases
JP2023181255A (ja) 疾病の予後と管理のための方法
JP6909208B2 (ja) Ｉｌ２３経路バイオマーカーを使用するｉｌ２３アンタゴニストに対する臨床応答の予測
Nuvolone et al. Cystatin F is a biomarker of prion pathogenesis in mice
US7709215B2 (en) Method for diagnosing and treating acute joint injury
BR112021015596A2 (pt) Distúrbios mediados pelo interferon tipo i
WO2013107826A2 (en) Use of cellular biomarkers expression to diagnose sepsis among intensive care patients
JP2023553247A (ja) がん診断のための組成物および方法
Chitadze et al. Erroneous expression of NKG2D on granulocytes detected by phycoerythrin‐conjugated clone 149810 antibody
EP2795337B1 (en) Screening methods to identify compounds useful in the prevention and/or treatment of inflammatory conditions
EP3861347B1 (en) Biomarkers for a combination therapy comprising lenvatinib and everolimus
US11761963B2 (en) Biomarker signature for predicting tumor response to anti-CD200 therapy
JP2022526131A (ja) 肝細胞癌診断用バイオマーカーセレブロンと、これに特異的な新規なモノクローナル抗体
JP2025529318A (ja) 造血幹細胞移植関連血栓性微小血管症（ｈｓｃｔ－ｔｍａ）を有する患者における診断及び予後バイオマーカプロファイル
JP5413915B2 (ja) 糖鎖認識受容体の新規用途
EP4560319A1 (en) Immune and tumour cells expression of vista in a panel of cancer indications
AU2015265578A1 (en) Risk-stratification of B-precursor acute lymphoblastic leukemia patients
WO2023042314A1 (ja) 免疫異常性炎症性疾患を治療または予防するための組成物
Class et al. Patent application title: SCREENING METHODS TO IDENTIFY COMPOUNDS USEFUL IN THE PREVENTION AND/OR TREATMENT OF INFLAMMATORY CONDITIONS Inventors: Reginald Christophe Xavier Brys (Mechelen, BE) Reginald Christophe Xavier Brys (Mechelen, BE) Sonia Dupont (Romainville, FR) Assignees: GALAPAGOS NV

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application