AU2018313028B2 - Compositions, methods and/or kits comprising a recombinant human CD38-extracellular domain - Google Patents

Compositions, methods and/or kits comprising a recombinant human CD38-extracellular domain Download PDF

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Publication number
AU2018313028B2
AU2018313028B2 AU2018313028A AU2018313028A AU2018313028B2 AU 2018313028 B2 AU2018313028 B2 AU 2018313028B2 AU 2018313028 A AU2018313028 A AU 2018313028A AU 2018313028 A AU2018313028 A AU 2018313028A AU 2018313028 B2 AU2018313028 B2 AU 2018313028B2
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pro
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AU2018313028A1 (en
Inventor
Jody Berry
Matteo Binda
Elizabeth Booth
Vincenzo Favaloro
John A. Hall
Peter Schwind
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Grifols Diagnostic Solutions Inc
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Grifols Diagnostic Solutions Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018313028A 2017-08-10 2018-06-01 Compositions, methods and/or kits comprising a recombinant human CD38-extracellular domain Active AU2018313028B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023204121A AU2023204121B2 (en) 2017-08-10 2023-06-28 Compositions, methods and/or kits comprising a recombinant human cd38-extracellular domain

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762543788P 2017-08-10 2017-08-10
US62/543,788 2017-08-10
PCT/IB2018/053939 WO2019030581A1 (en) 2017-08-10 2018-06-01 COMPOSITIONS, METHODS AND / OR KITS COMPRISING AN EXTRACELLULAR DOMAIN OF RECOMBINANT HUMAN CD38

Related Child Applications (1)

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AU2023204121A Division AU2023204121B2 (en) 2017-08-10 2023-06-28 Compositions, methods and/or kits comprising a recombinant human cd38-extracellular domain

Publications (2)

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AU2018313028A1 AU2018313028A1 (en) 2020-02-20
AU2018313028B2 true AU2018313028B2 (en) 2023-05-25

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AU2018313028A Active AU2018313028B2 (en) 2017-08-10 2018-06-01 Compositions, methods and/or kits comprising a recombinant human CD38-extracellular domain
AU2023204121A Active AU2023204121B2 (en) 2017-08-10 2023-06-28 Compositions, methods and/or kits comprising a recombinant human cd38-extracellular domain

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US (3) US11708418B2 (https=)
EP (3) EP3587445B1 (https=)
JP (3) JP6833851B2 (https=)
KR (2) KR102631281B1 (https=)
CN (2) CN117820498A (https=)
AR (1) AR112357A1 (https=)
AU (2) AU2018313028B2 (https=)
BR (1) BR112020002636A2 (https=)
CA (1) CA3070789A1 (https=)
EA (1) EA202090265A1 (https=)
ES (2) ES2911243T3 (https=)
HU (1) HUE065510T2 (https=)
MX (3) MX2020001489A (https=)
PL (1) PL3587445T3 (https=)
PT (1) PT3587445T (https=)
TW (1) TW201910349A (https=)
UY (1) UY37757A (https=)
WO (1) WO2019030581A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE065510T2 (hu) * 2017-08-10 2024-05-28 Grifols Diagnostic Solutions Inc Immunglobulin Fc-régiót és poli-His domént tartalmazó oligomerizációs címke
US11746140B2 (en) * 2018-02-20 2023-09-05 F. Hoffman-La Roche Ag Composition comprising recombinant GPlbα receptor protein
CN112048019B (zh) * 2019-06-06 2023-05-09 鲁南制药集团股份有限公司 抗人cd47单克隆抗体
CN116635420A (zh) * 2020-09-10 2023-08-22 英创远达制药公司 血液筛查方法
KR20230066404A (ko) 2020-09-10 2023-05-15 카시 파마슈티컬스, 인코포레이티드 혈액 스크리닝 방법
CN112285361B (zh) * 2020-09-27 2023-12-05 中国人民解放军空军军医大学 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂
CN114917413B (zh) * 2022-06-14 2023-04-28 健诺维(成都)生物科技有限公司 一种负载重组多肽的羊膜及其制备方法
WO2024172419A1 (ko) * 2023-02-16 2024-08-22 주식회사 디엔티 Cd38 또는 이의 단편을 포함하는 자가면역질환 치료용 조성물
CN117723749B (zh) * 2024-02-07 2024-06-04 南昌大学 基于分子粘合剂的动态光散射免疫传感检测方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016071355A1 (en) * 2014-11-04 2016-05-12 Glenmark Pharmaceuticals S.A. Cd3/cd38 t cell retargeting hetero-dimeric immunoglobulins and methods of their production

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994511A (en) * 1997-07-02 1999-11-30 Genentech, Inc. Anti-IgE antibodies and methods of improving polypeptides
US6506551B1 (en) * 1999-10-08 2003-01-14 North Shore - Long Island Jewish Research Institute CD38 as a prognostic indicator in B cell chronic lymphocytic leukemia
AU2001273121A1 (en) * 2000-06-30 2002-01-14 Pharmacia And Upjohn Company Recombinant staphylococcus aureus peptide deformylase
EP1697520A2 (en) * 2003-12-22 2006-09-06 Xencor, Inc. Fc polypeptides with novel fc ligand binding sites
AU2005235811B2 (en) * 2004-02-06 2011-11-03 Morphosys Ag Anti-CD38 human antibodies and uses therefor
WO2008037257A2 (en) * 2006-09-26 2008-04-03 Genmab A/S Anti-cd38 plus corticosteroids plus a non-corticosteroid chemotherapeutic for treating tumors
EP1914242A1 (en) * 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
PL2185589T3 (pl) * 2007-06-01 2016-09-30 Środki wiążące receptor regionu stałego Fc immunoglobuliny
EP2573112A1 (en) * 2007-10-11 2013-03-27 The Hospital For Sick Children Modulation of sirpa - cd47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
EP2370467B1 (en) * 2008-10-01 2016-09-07 Amgen Research (Munich) GmbH Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
DK2352763T4 (da) * 2008-10-01 2022-10-17 Amgen Res Munich Gmbh Bispecifikke enkeltkædede antistoffer med specificitet for højmolekylære målantigener
WO2010083253A2 (en) * 2009-01-14 2010-07-22 Viral Logic Systems Technology Corp. Cd47 related compositions and methods for treating immunological diseases and disorders
HUE030100T2 (en) * 2010-02-19 2017-04-28 Xencor Inc New CTLA4-IG immunoadhesins
US20130029358A1 (en) * 2010-04-01 2013-01-31 Ludwig Institute For Cancer Research Ltd. Immunodominant mhc dr52b restricted ny-eso-1 epitopes, mhc class ii monomers and multimers, and uses thereof
AU2011295715B9 (en) * 2010-09-03 2017-02-23 Abbvie Stemcentrx Llc Novel modulators and methods of use
EP2530089A1 (en) * 2011-06-03 2012-12-05 Bayer Pharma Aktiengesellschaft Neutralising prolactin receptor antibody Mat3 and its therapeutical use
KR102100388B1 (ko) * 2012-02-06 2020-04-13 인히브릭스, 인크. Cd47 항체 및 그 사용 방법
US9926373B2 (en) * 2012-04-27 2018-03-27 Novo Nordisk A/S Human CD30 ligand antigen binding proteins
CN104736174B (zh) * 2012-07-06 2019-06-14 根马布私人有限公司 具有三重突变的二聚体蛋白质
US9447193B2 (en) * 2013-03-24 2016-09-20 Development Center For Biotechnology Methods for suppressing cancer by inhibition of TMCC3
WO2015191546A2 (en) * 2014-06-10 2015-12-17 The Board Of Regents Of The University Of Texas System Adp-ribose detection reagents
WO2015195531A2 (en) * 2014-06-18 2015-12-23 Albert Einstein College Of Medicine, Inc. Syntac polypeptides and uses thereof
EP3221358B1 (en) * 2014-11-18 2021-07-21 Janssen Pharmaceutica, N.V. Cd47 antibodies, methods, and uses
JP6649941B2 (ja) * 2015-02-16 2020-02-19 株式会社ファーマフーズ Fstl1を利用した抗がん剤・転移抑制剤およびその併用剤
US9944679B2 (en) * 2015-03-16 2018-04-17 The Catholic University Of America Authentic trimeric HIV-1 envelope glycoproteins comprising a long linker and tag
PE20171790A1 (es) * 2015-03-23 2017-12-28 Bayer Pharma AG Anticuerpos anti-ceacam6 y sus usos
WO2017043466A1 (ja) * 2015-09-08 2017-03-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗EphA4抗体
AU2016352676A1 (en) * 2015-11-10 2018-05-31 University Medical Center Hamburg - Eppendorf ANTIGEN-binding polypeptides directed against CD38
HUE065510T2 (hu) * 2017-08-10 2024-05-28 Grifols Diagnostic Solutions Inc Immunglobulin Fc-régiót és poli-His domént tartalmazó oligomerizációs címke

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016071355A1 (en) * 2014-11-04 2016-05-12 Glenmark Pharmaceuticals S.A. Cd3/cd38 t cell retargeting hetero-dimeric immunoglobulins and methods of their production

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AKIRA TOHGO ET AL, JOURNAL OF BIOLOGICAL CHEMISTRY, US, (1997-02-14), vol. 272, no. 7, doi:10.1074/jbc.272.7.3879, ISSN 0021-9258, pages 3879 - 3882 *
J. DECKERT ET AL, CLINICAL CANCER RESEARCH, US, (2014-09-01), vol. 20, no. 17, doi:10.1158/1078-0432.CCR-14-0695, ISSN 1078-0432, pages 4574 - 4583 *
KHOO K M ET AL, PROTEIN EXPRESSION AND PURIFICAT, ACADEMIC PRESS, SAN DIEGO, CA, (2005-04-01), vol. 40, no. 2, doi:10.1016/J.PEP.2004.11.010, ISSN 1046-5928, pages 396 - 403 *

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Publication number Publication date
JP7289328B2 (ja) 2023-06-09
CN109790210B (zh) 2024-03-26
EP3464343A1 (en) 2019-04-10
JP2021088567A (ja) 2021-06-10
JP2019527533A (ja) 2019-10-03
MX2024008109A (es) 2024-07-19
CA3070789A1 (en) 2019-02-14
AR112357A1 (es) 2019-10-23
US11708418B2 (en) 2023-07-25
KR20240015159A (ko) 2024-02-02
JP2023041802A (ja) 2023-03-24
TW201910349A (zh) 2019-03-16
MX2024005669A (es) 2024-05-30
CN117820498A (zh) 2024-04-05
US20240132616A1 (en) 2024-04-25
EP4296680A2 (en) 2023-12-27
EP4296680A3 (en) 2024-03-20
EP3587445A1 (en) 2020-01-01
BR112020002636A2 (pt) 2020-07-28
EA202090265A1 (ru) 2020-06-05
AU2023204121B2 (en) 2026-04-23
PL3587445T3 (pl) 2024-04-29
HUE065510T2 (hu) 2024-05-28
AU2023204121A1 (en) 2023-07-20
ES2911243T3 (es) 2022-05-18
PT3587445T (pt) 2024-03-14
EP3464343B1 (en) 2022-03-23
JP6833851B2 (ja) 2021-02-24
ES2973864T3 (es) 2024-06-24
CN109790210A (zh) 2019-05-21
KR20200035194A (ko) 2020-04-02
WO2019030581A1 (en) 2019-02-14
MX2020001489A (es) 2020-03-20
EP3587445B1 (en) 2023-12-13
UY37757A (es) 2018-11-30
US20240092929A1 (en) 2024-03-21
US20210198376A1 (en) 2021-07-01
KR102631281B1 (ko) 2024-01-30
AU2018313028A1 (en) 2020-02-20
US20240228651A9 (en) 2024-07-11

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