AU2018276434B2 - Long-acting GIP peptide analogues - Google Patents
Long-acting GIP peptide analogues Download PDFInfo
- Publication number
- AU2018276434B2 AU2018276434B2 AU2018276434A AU2018276434A AU2018276434B2 AU 2018276434 B2 AU2018276434 B2 AU 2018276434B2 AU 2018276434 A AU2018276434 A AU 2018276434A AU 2018276434 A AU2018276434 A AU 2018276434A AU 2018276434 B2 AU2018276434 B2 AU 2018276434B2
- Authority
- AU
- Australia
- Prior art keywords
- seq
- hgip
- amino acid
- gip
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17173628 | 2017-05-31 | ||
| EP17173628.3 | 2017-05-31 | ||
| PCT/EP2018/064355 WO2018220123A1 (en) | 2017-05-31 | 2018-05-31 | Long-acting gip peptide analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2018276434A1 AU2018276434A1 (en) | 2020-01-02 |
| AU2018276434B2 true AU2018276434B2 (en) | 2021-12-16 |
Family
ID=59021262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018276434A Active AU2018276434B2 (en) | 2017-05-31 | 2018-05-31 | Long-acting GIP peptide analogues |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11572399B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3630806B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2020521784A (cg-RX-API-DMAC7.html) |
| KR (1) | KR102743887B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN110691788B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2018276434B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019025195A8 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2972848T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL3630806T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018220123A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2685987T3 (es) | 2014-09-05 | 2018-10-15 | University Of Copenhagen | Análogos de péptidos gip |
| BR112019025195A8 (pt) | 2017-05-31 | 2020-07-07 | Univ Copenhagen | análogos do peptídeo gip de ação prolongada |
| CA3097939A1 (en) | 2018-05-04 | 2019-11-07 | Novo Nordisk A/S | Gip derivatives and uses thereof |
| US12187773B2 (en) * | 2018-12-03 | 2025-01-07 | Antag Therapeutics Aps | Modified GIP peptide analogues |
| WO2023139106A2 (en) | 2022-01-18 | 2023-07-27 | Novo Nordisk A/S | Long-acting gipr antagonists |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088379A2 (en) * | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
| WO1998024464A1 (en) | 1996-12-03 | 1998-06-11 | Trustees Of Boston University | Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) |
| BR9906857A (pt) | 1998-01-30 | 2000-11-14 | Novo Nordisk As | Seringas de injeção |
| WO1999043708A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| DE69918070T2 (de) | 1998-03-13 | 2005-08-25 | Novo Nordisk A/S | Stabilisierte, wässrige Glukagonlösungen, enthaltend Detergenzien |
| EP1119625B1 (en) | 1998-10-07 | 2005-06-29 | Medical College Of Georgia Research Institute, Inc. | Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
| PL202367B1 (pl) | 1998-12-07 | 2009-06-30 | Sod Conseils Rech Applic | Związki stanowiące analogi GLP-1, kompozycje zawierające te związki oraz zastosowanie tych związków |
| US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
| DE60012721T4 (de) | 1999-03-29 | 2010-09-09 | Uutech Ltd., Coleraine | Analoge des magensaft inhibierenden peptides und ihre verwendung für die behandlung von diabetes |
| GB0404124D0 (en) * | 2004-02-25 | 2004-03-31 | Univ Ulster | Antagonists of GIP |
| ATE406384T1 (de) | 2000-12-07 | 2008-09-15 | Lilly Co Eli | Glp-1 fusion proteine |
| US20030232761A1 (en) | 2002-03-28 | 2003-12-18 | Hinke Simon A. | Novel analogues of glucose-dependent insulinotropic polypeptide |
| WO2004067548A2 (en) | 2003-01-31 | 2004-08-12 | Theratechnologies Inc. | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| BRPI0606992A2 (pt) | 2005-02-11 | 2009-07-28 | Amylin Pharmaceuticals Inc | análogo e polipeptìdeos hìbridos de gip com propriedades selecionáveis |
| US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| JP5412273B2 (ja) | 2006-03-21 | 2014-02-12 | アミリン・ファーマシューティカルズ,リミテッド・ライアビリティ・カンパニー | ペプチド−ぺプチダーゼ阻害剤及びその使用 |
| AU2007284365A1 (en) * | 2006-08-17 | 2008-02-21 | Amylin Pharmaceuticals, Inc. | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
| WO2010016936A1 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Pharmaceutical compositions of analogues of glucose-dependent insulinotropic polypeptide |
| PL2320923T3 (pl) | 2008-08-07 | 2015-06-30 | Ipsen Pharma Sas | Skrócone analogi peptydu insulinotropowego zależnego od glukozy |
| CA2732973A1 (en) | 2008-08-07 | 2010-02-11 | Ipsen Pharma S.A.S. | Glucose-dependent insulinotropic polypeptide analogues |
| CN102171244B (zh) | 2008-08-07 | 2015-05-13 | 益普生制药股份有限公司 | 糖依赖性胰岛素释放肽的类似物 |
| US8999940B2 (en) | 2008-08-07 | 2015-04-07 | Ipsen Pharma S.A.S. | Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal |
| US8551946B2 (en) * | 2010-01-27 | 2013-10-08 | Indiana University Research And Technology Corporation | Glucagon antagonist-GIP agonist conjugates and compositions for the treatment of metabolic disorders and obesity |
| US9023986B2 (en) | 2010-10-25 | 2015-05-05 | Hoffmann-La Roche Inc. | Glucose-dependent insulinotropic peptide analogs |
| EP2717925A1 (en) * | 2011-06-10 | 2014-04-16 | Universität Bern | Imaging and treatment of neuroendocrine tumors with glucose - dependent insulinotropic polypeptide or analogues or antagonists thereof |
| JP5914641B2 (ja) * | 2011-06-10 | 2016-05-11 | ベイジン・ハンミ・ファーマシューティカル・カンパニー・リミテッドBeijing Hanmi Pharmaceutical Co., Ltd. | グルコース依存性インスリン分泌刺激ポリペプチドのアナログ、医薬組成物及びその使用 |
| EP2986314A4 (en) | 2013-03-15 | 2016-04-13 | Univ Indiana Res & Tech Corp | PRODRUGS WITH EXTENDED EFFECT |
| ES2685987T3 (es) * | 2014-09-05 | 2018-10-15 | University Of Copenhagen | Análogos de péptidos gip |
| AU2015340586B2 (en) * | 2014-10-29 | 2020-04-30 | Zealand Pharma A/S | GIP agonist compounds and methods |
| EP3310376A4 (en) | 2015-06-17 | 2019-01-23 | The California Institute for Biomedical Research | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF |
| WO2018069442A1 (en) * | 2016-10-12 | 2018-04-19 | University Of Copenhagen | Peptide dual agonists of gipr and glp2r |
| EP3560515B1 (en) | 2016-12-26 | 2023-11-15 | Kao Corporation | Gip inhibitors for use in improving motor control function |
| EP3569248B1 (en) | 2016-12-26 | 2023-12-06 | Kao Corporation | Gip inhibitors for improving cognitive function |
| JP7158142B2 (ja) | 2016-12-26 | 2022-10-21 | 花王株式会社 | 低体温改善剤 |
| BR112019025195A8 (pt) | 2017-05-31 | 2020-07-07 | Univ Copenhagen | análogos do peptídeo gip de ação prolongada |
-
2018
- 2018-05-31 BR BR112019025195A patent/BR112019025195A8/pt unknown
- 2018-05-31 PL PL18728872.5T patent/PL3630806T3/pl unknown
- 2018-05-31 ES ES18728872T patent/ES2972848T3/es active Active
- 2018-05-31 EP EP18728872.5A patent/EP3630806B1/en active Active
- 2018-05-31 EP EP24150677.3A patent/EP4361173A3/en active Pending
- 2018-05-31 WO PCT/EP2018/064355 patent/WO2018220123A1/en not_active Ceased
- 2018-05-31 CN CN201880036341.0A patent/CN110691788B/zh active Active
- 2018-05-31 JP JP2019565921A patent/JP2020521784A/ja active Pending
- 2018-05-31 US US16/617,698 patent/US11572399B2/en active Active
- 2018-05-31 AU AU2018276434A patent/AU2018276434B2/en active Active
- 2018-05-31 KR KR1020197034279A patent/KR102743887B1/ko active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088379A2 (en) * | 2010-12-22 | 2012-06-28 | Marcadia Biotech, Inc. | Methods for treating metabolic disorders and obesity with gip and glp-1 receptor-active glucagon-based peptides |
Non-Patent Citations (1)
| Title |
|---|
| PATHAK V ET AL, MOLECULAR AND CELLULAR ENDOCRINOLOGY, (2014-11-06), vol. 401, doi:10.1016/J.MCE.2014.10.025, ISSN 0303-7207, pages 120 - 129 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2972848T3 (es) | 2024-06-17 |
| PL3630806T3 (pl) | 2024-05-13 |
| BR112019025195A2 (pt) | 2020-06-23 |
| CN110691788B (zh) | 2024-05-31 |
| KR20200014287A (ko) | 2020-02-10 |
| KR102743887B1 (ko) | 2024-12-19 |
| BR112019025195A8 (pt) | 2020-07-07 |
| US20200087373A1 (en) | 2020-03-19 |
| CN110691788A (zh) | 2020-01-14 |
| AU2018276434A1 (en) | 2020-01-02 |
| JP2020521784A (ja) | 2020-07-27 |
| WO2018220123A1 (en) | 2018-12-06 |
| CA3064510A1 (en) | 2018-12-06 |
| EP4361173A3 (en) | 2024-07-03 |
| EP3630806B1 (en) | 2024-01-10 |
| EP4361173A2 (en) | 2024-05-01 |
| EP3630806A1 (en) | 2020-04-08 |
| US11572399B2 (en) | 2023-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |