AU2018226867B2 - ECM hydrogel for treating esophageal inflammation - Google Patents

ECM hydrogel for treating esophageal inflammation Download PDF

Info

Publication number
AU2018226867B2
AU2018226867B2 AU2018226867A AU2018226867A AU2018226867B2 AU 2018226867 B2 AU2018226867 B2 AU 2018226867B2 AU 2018226867 A AU2018226867 A AU 2018226867A AU 2018226867 A AU2018226867 A AU 2018226867A AU 2018226867 B2 AU2018226867 B2 AU 2018226867B2
Authority
AU
Australia
Prior art keywords
ecm
hydrogel
esophagus
esophageal
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2018226867A
Other languages
English (en)
Other versions
AU2018226867A1 (en
Inventor
Stephen Francis Badylak
Juan Diego Naranjo Gutierrez
Lindsey Tamiko Saldin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Publication of AU2018226867A1 publication Critical patent/AU2018226867A1/en
Application granted granted Critical
Publication of AU2018226867B2 publication Critical patent/AU2018226867B2/en
Priority to AU2024200617A priority Critical patent/AU2024200617B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018226867A 2017-03-02 2018-03-02 ECM hydrogel for treating esophageal inflammation Active AU2018226867B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024200617A AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762465985P 2017-03-02 2017-03-02
US62/465,985 2017-03-02
PCT/US2018/020758 WO2018161028A1 (en) 2017-03-02 2018-03-02 Ecm hydrogel for treating esophageal inflammation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024200617A Division AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Publications (2)

Publication Number Publication Date
AU2018226867A1 AU2018226867A1 (en) 2019-08-22
AU2018226867B2 true AU2018226867B2 (en) 2023-11-02

Family

ID=63371156

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018226867A Active AU2018226867B2 (en) 2017-03-02 2018-03-02 ECM hydrogel for treating esophageal inflammation
AU2024200617A Active AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024200617A Active AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Country Status (9)

Country Link
US (3) US11213545B2 (enExample)
EP (2) EP4252842B1 (enExample)
JP (3) JP7203428B2 (enExample)
KR (1) KR102745611B1 (enExample)
CN (1) CN110352061A (enExample)
AU (2) AU2018226867B2 (enExample)
CA (1) CA3052489A1 (enExample)
ES (2) ES3039679T3 (enExample)
WO (1) WO2018161028A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3119448B1 (en) 2014-03-21 2020-04-22 University of Pittsburgh- Of the Commonwealth System of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
EP4268892B1 (en) 2016-03-02 2025-01-29 University of Pittsburgh- Of the Commonwealth System of Higher Education Matrix bound nanovesicles and their use
ES3039679T3 (en) 2017-03-02 2025-10-23 Univ Pittsburgh Commonwealth Sys Higher Education Ecm hydrogel for treating esophageal inflammation
EP3589294B1 (en) 2017-03-02 2022-10-26 University of Pittsburgh - Of the Commonwealth System of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for use in the treatment of cancer
ES2945740T3 (es) 2017-05-05 2023-07-06 Univ Pittsburgh Commonwealth Sys Higher Education Aplicaciones oculares de vesículas unidas a matriz (MBV)
KR20210005942A (ko) 2018-05-03 2021-01-15 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 Il-33을 포함하는 매트릭스 결합 소포 (mbvs) 및 그 용도
JP2021529024A (ja) 2018-06-21 2021-10-28 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 食道粘膜下流体クッションとしての細胞外マトリックス(ecm)ヒドロゲルの使用
CA3103973A1 (en) * 2018-06-21 2019-12-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of a urinary bladder ecm hydrogel as an esophageal submucosal fluid cushion
AU2019288588B2 (en) * 2018-06-21 2024-06-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel as a submucosal fluid cushion
KR20210142003A (ko) * 2019-03-13 2021-11-23 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 음향 세포외 기질 하이드로겔 및 이의 용도
JP2023514821A (ja) * 2020-02-28 2023-04-11 テキサス メディカル センター 癒着阻止および組織治癒向上のための噴霧可能刺激応答性マイクロヒドロゲル
EP4230725A4 (en) * 2020-11-17 2025-02-12 Cellartgen Inc. ESOPHAGEAL EXTRACELLULAR MATRIX DERIVED SCAFFOLD FOR ESOPHAGEAL ORGANOID CULTURE AND TRANSPLANTATION, AND PRODUCTION METHOD THEREOF

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018161034A1 (en) * 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for the treatment of cancer

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155095A (en) 1961-02-07 1964-11-03 Adolph M Brown Anastomosis method and means
US4294241A (en) 1977-06-09 1981-10-13 Teruo Miyata Collagen skin dressing
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4563350A (en) 1984-10-24 1986-01-07 Collagen Corporation Inductive collagen based bone repair preparations
US4978668A (en) 1986-09-02 1990-12-18 Purdue Research Foundation Treatment to reduce ischemic tissue injury
US4956178A (en) 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US5007927A (en) 1989-10-24 1991-04-16 Purdue Research Foundation Muscle-powered cardiac assist device
US5281422A (en) 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5354274A (en) 1992-08-20 1994-10-11 Methodist Hospital Of Indiana, Inc. Device for oral administration of liquids
US5275826A (en) 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5641518A (en) 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5352463A (en) 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor
US6653291B1 (en) 1992-11-13 2003-11-25 Purdue Research Foundation Composition and method for production of transformed cells
ATE219343T1 (de) 1994-04-29 2002-07-15 Scimed Life Systems Inc Stent mit kollagen
US6475232B1 (en) 1996-12-10 2002-11-05 Purdue Research Foundation Stent with reduced thrombogenicity
US5695998A (en) 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5554389A (en) 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
DE69622548T2 (de) 1995-04-07 2003-09-18 Methodist Health Group, Inc. Gewebetransplantat zur blasenrekonstruktion
US5711969A (en) 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
CA2160647C (en) 1995-10-16 2002-05-28 Thomas William Garay Helical bearing anchor catcher
US5755791A (en) 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
BR9711166A (pt) 1996-08-23 1999-08-17 Cook Biotech Inc PrÄtese de enxerto materiais para sua prepara-Æo e m-todos para seu uso
CA2263898C (en) 1996-09-16 2009-12-08 Purdue Research Foundation Composition and method for repairing neurological tissue
CA2267449C (en) 1996-11-05 2008-10-14 Purdue Research Foundation Myocardial graft constructs
TW510803B (en) 1996-11-20 2002-11-21 Yasuhiko Shimizu Man-made esophagus and its manufacturing method
US6375989B1 (en) 1996-12-10 2002-04-23 Purdue Research Foundation Submucosa extracts
AU736572B2 (en) 1996-12-10 2001-08-02 Purdue Research Foundation Artificial vascular valves
WO1998025636A1 (en) 1996-12-10 1998-06-18 Purdue Research Foundation Stomach submucosa derived tissue graft
CA2274033C (en) 1996-12-10 2010-05-11 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
AU743779B2 (en) 1996-12-10 2002-02-07 Cook Biotech, Inc. Tubular grafts from purified submucosa
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
EP1011699B1 (en) 1997-09-11 2001-12-05 Purdue Research Foundation Galactosidase modified submucosal tissue
WO1999043786A2 (en) 1998-02-27 1999-09-02 Purdue Research Foundation Submucosa gel compositions
US6448076B2 (en) 1998-09-15 2002-09-10 The Regents Of The University Of Michigan Method for chemically acellularizing a biological tissue sample
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
AU759272B2 (en) 1998-12-01 2003-04-10 Medical College Of Ohio At Toledo Submucosa modulation of mammalian immune response
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
AU2001284968B2 (en) 2000-08-16 2006-12-21 Duke University Decellularized tissue engineered constructs and tissues
EP1343492B1 (en) * 2000-11-22 2006-02-01 Rxkinetix, Inc. Treatment of mucositis
AU2003202261A1 (en) 2002-01-11 2003-07-30 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
WO2003059284A2 (en) 2002-01-11 2003-07-24 Purdue Research Foundation Composition and method for inhibiting hypersensitivity
CN1665527A (zh) 2002-05-02 2005-09-07 普渡研究基金会 血管化增强的移植构造物
CN1713861A (zh) 2002-05-02 2005-12-28 普渡研究基金会 血管化增强的移植构造物
NZ536563A (en) 2002-05-02 2008-03-28 Purdue Research Foundation Vascularization enhanced graft constructs
US7402319B2 (en) 2002-09-27 2008-07-22 Board Of Regents, The University Of Texas System Cell-free tissue replacement for tissue engineering
US20040191226A1 (en) 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
US20040187877A1 (en) 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
US20040176855A1 (en) 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US20040175366A1 (en) 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
AU2004253508A1 (en) 2003-06-25 2005-01-13 Acell, Inc. Conditioned matrix compositions for tissue restoration
US7326571B2 (en) 2003-07-17 2008-02-05 Boston Scientific Scimed, Inc. Decellularized bone marrow extracellular matrix
US8021692B2 (en) 2003-08-25 2011-09-20 Cook Biotech Incorporated Graft materials containing bioactive substances, and methods for their manufacture
US8741352B2 (en) 2003-08-25 2014-06-03 Cook Biotech Incorporated Graft materials containing ECM components, and methods for their manufacture
KR101084563B1 (ko) 2004-03-19 2011-11-17 도요타 지도샤(주) 자동차용 바이저
US7905826B2 (en) 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
US8874204B2 (en) 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US9138445B2 (en) 2005-03-09 2015-09-22 Cook Biotech Incorporated Medical graft materials with adherent extracellular matrix fibrous mass
WO2007005792A2 (en) 2005-07-01 2007-01-11 University Of Pittsburgh Wound healing polymeric networks
WO2007084278A2 (en) 2006-01-06 2007-07-26 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix based gastroesophageal junction reinforcement device
US8241908B2 (en) 2006-05-16 2012-08-14 Becton, Dickinson And Company Extracellular matrix coated surface for culturing cells
WO2008008266A2 (en) 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
CN106390200A (zh) 2006-10-23 2017-02-15 库克生物科技公司 组分特性增强的处理的ecm材料
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
US20110184439A1 (en) 2008-05-09 2011-07-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biological Matrix for Cardiac Repair
US9277999B2 (en) 2009-02-27 2016-03-08 University of Pittsburgh—of the Commonwealth System of Higher Education Joint bioscaffolds
WO2011044443A2 (en) 2009-10-09 2011-04-14 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Matricryptic ecm peptides for tissue reconstruction
US9814744B2 (en) 2009-12-22 2017-11-14 University of Pittsburg—Of the Commonwealth System of Higher Education Decellularized adipose cell growth scaffold
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
CA2832811A1 (en) 2011-04-12 2012-10-18 Novo Nordisk A/S Double-acylated glp-1 derivatives
US20140356331A1 (en) 2011-07-08 2014-12-04 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Injectable cns-derived ecm for tissue reconstruction
US20140227364A1 (en) 2013-02-08 2014-08-14 Kimberly A. Kentner Methods of manufacturing bioactive gels from extracellular matrix material
AU2014251110A1 (en) 2013-04-08 2015-11-26 Regentys Corporation Method and composition for treating inflammatory bowel disease without colectomy
US9861662B2 (en) 2013-07-03 2018-01-09 University of Pittsburgh—of the Commonwealth System of Higher Education Bone-derived extra cellular matrix gel
ITMI20131924A1 (it) 2013-11-20 2015-05-21 Cosmo Technologies Ltd Emulsions or microemulsions for use in endoscopic mucosal resectioning and/or endoscopic submucosal dissection emulsioni o microemulsioni per uso nella resezione mucosale endoscopica e/o dissezione submucosale endoscopica
US10286119B2 (en) 2014-01-24 2019-05-14 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix mesh coating
EP3119448B1 (en) 2014-03-21 2020-04-22 University of Pittsburgh- Of the Commonwealth System of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
US20170049932A1 (en) 2014-04-24 2017-02-23 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Fractionating Extracellular Matrix to Modulate Bioactivity and the Host Response
EP3319653A4 (en) 2015-07-10 2019-03-27 University of Pittsburgh - Of the Commonwealth System of Higher Education METHOD FOR PRODUCING ECM EQUIPMENT AND HYDROGELS FROM COLON
WO2017044787A1 (en) 2015-09-10 2017-03-16 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Bi-layer extra cellular matrix scaffolds and uses therefor
ES2873519T3 (es) 2015-09-18 2021-11-03 Univ Pittsburgh Commonwealth Sys Higher Education Matriz extracelular soluble no gelificante con actividad biológica
AU2017207015B2 (en) 2016-01-13 2022-08-04 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Vascular extracellular matrix hydrogel
EP4268892B1 (en) 2016-03-02 2025-01-29 University of Pittsburgh- Of the Commonwealth System of Higher Education Matrix bound nanovesicles and their use
CA3017747A1 (en) 2016-03-14 2017-09-21 Regentys Corporation Method and composition for treating inflammatory bowel disease
ES3039679T3 (en) 2017-03-02 2025-10-23 Univ Pittsburgh Commonwealth Sys Higher Education Ecm hydrogel for treating esophageal inflammation
US11389569B2 (en) 2017-04-03 2022-07-19 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler
ES2945740T3 (es) 2017-05-05 2023-07-06 Univ Pittsburgh Commonwealth Sys Higher Education Aplicaciones oculares de vesículas unidas a matriz (MBV)
US12329883B2 (en) 2017-10-24 2025-06-17 Davol Inc. Soft tissue repair implants comprising hydroxybutyrate
KR20210005942A (ko) 2018-05-03 2021-01-15 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 Il-33을 포함하는 매트릭스 결합 소포 (mbvs) 및 그 용도

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018161034A1 (en) * 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for the treatment of cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TIMOTHY J. KEANE ET AL: "Tissue-Specific Effects of Esophageal Extracellular Matrix", TISSUE ENGINEERING PART A, vol. 21, no. 17-18, 1 September 2015 pages 2293 - 2300, *

Also Published As

Publication number Publication date
EP4252842A3 (en) 2023-10-25
JP2023024578A (ja) 2023-02-16
CN110352061A (zh) 2019-10-18
AU2024200617B2 (en) 2025-10-23
EP4252842A2 (en) 2023-10-04
US20240189349A1 (en) 2024-06-13
JP7681909B2 (ja) 2025-05-23
US20200009187A1 (en) 2020-01-09
ES2957291T3 (es) 2024-01-16
US12303533B2 (en) 2025-05-20
EP3589292A1 (en) 2020-01-08
KR20190120258A (ko) 2019-10-23
EP3589292A4 (en) 2020-12-09
CA3052489A1 (en) 2018-09-07
JP7203428B2 (ja) 2023-01-13
US11707485B2 (en) 2023-07-25
US11213545B2 (en) 2022-01-04
AU2024200617A1 (en) 2024-02-22
ES3039679T3 (en) 2025-10-23
JP2025019254A (ja) 2025-02-06
AU2018226867A1 (en) 2019-08-22
EP4252842B1 (en) 2025-06-25
US20220249549A1 (en) 2022-08-11
WO2018161028A1 (en) 2018-09-07
KR102745611B1 (ko) 2024-12-20
EP3589292B1 (en) 2023-08-23
JP2020509048A (ja) 2020-03-26

Similar Documents

Publication Publication Date Title
AU2024200617B2 (en) Ecm hydrogel for treating esophageal inflammation
JP7412777B2 (ja) 粘膜下流体クッションとしての細胞外マトリックス(ecm)ヒドロゲル
AU2024219503A1 (en) Use of a urinary bladder ecm hydrogel as an esophageal submucosal fluid cushion
JP2024060075A (ja) 食道粘膜下流体クッションとしての細胞外マトリックス(ecm)ヒドロゲルの使用
HK40091837B (en) Ecm hydrogel for treating esophageal inflammation
HK40091837A (en) Ecm hydrogel for treating esophageal inflammation
HK40012466B (en) Ecm hydrogel for treating esophageal inflammation
HK40012466A (en) Ecm hydrogel for treating esophageal inflammation

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)