AU2018226867B2 - ECM hydrogel for treating esophageal inflammation - Google Patents

ECM hydrogel for treating esophageal inflammation Download PDF

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Publication number
AU2018226867B2
AU2018226867B2 AU2018226867A AU2018226867A AU2018226867B2 AU 2018226867 B2 AU2018226867 B2 AU 2018226867B2 AU 2018226867 A AU2018226867 A AU 2018226867A AU 2018226867 A AU2018226867 A AU 2018226867A AU 2018226867 B2 AU2018226867 B2 AU 2018226867B2
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Australia
Prior art keywords
ecm
hydrogel
esophagus
esophageal
subject
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AU2018226867A1 (en
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Stephen Francis Badylak
Juan Diego Naranjo Gutierrez
Lindsey Tamiko Saldin
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University of Pittsburgh
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University of Pittsburgh
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Priority to AU2024200617A priority Critical patent/AU2024200617B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018226867A 2017-03-02 2018-03-02 ECM hydrogel for treating esophageal inflammation Active AU2018226867B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024200617A AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762465985P 2017-03-02 2017-03-02
US62/465,985 2017-03-02
PCT/US2018/020758 WO2018161028A1 (en) 2017-03-02 2018-03-02 Ecm hydrogel for treating esophageal inflammation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024200617A Division AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Publications (2)

Publication Number Publication Date
AU2018226867A1 AU2018226867A1 (en) 2019-08-22
AU2018226867B2 true AU2018226867B2 (en) 2023-11-02

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Application Number Title Priority Date Filing Date
AU2018226867A Active AU2018226867B2 (en) 2017-03-02 2018-03-02 ECM hydrogel for treating esophageal inflammation
AU2024200617A Active AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024200617A Active AU2024200617B2 (en) 2017-03-02 2024-02-01 Ecm hydrogel for treating esophageal inflammation

Country Status (9)

Country Link
US (3) US11213545B2 (cg-RX-API-DMAC7.html)
EP (2) EP4252842B1 (cg-RX-API-DMAC7.html)
JP (3) JP7203428B2 (cg-RX-API-DMAC7.html)
KR (1) KR102745611B1 (cg-RX-API-DMAC7.html)
CN (1) CN110352061A (cg-RX-API-DMAC7.html)
AU (2) AU2018226867B2 (cg-RX-API-DMAC7.html)
CA (1) CA3052489A1 (cg-RX-API-DMAC7.html)
ES (2) ES3039679T3 (cg-RX-API-DMAC7.html)
WO (1) WO2018161028A1 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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AU2015231110B2 (en) 2014-03-21 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
US20190117837A1 (en) 2016-03-02 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
US11213545B2 (en) 2017-03-02 2022-01-04 University of Pittsburgh—of the Commonwealth System of Higher Education ECM hydrogel for treating esophageal inflammation
JP7282380B2 (ja) 2017-03-02 2023-05-29 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション がんを処置するための細胞外マトリクス（ｅｃｍ）ヒドロゲルおよびその可溶性画分
AU2018261022B2 (en) 2017-05-05 2024-02-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ocular applications of matrix bound vesicles (MBVs)
EP3787642A4 (en) 2018-05-03 2022-09-21 University of Pittsburgh - of the Commonwealth System of Higher Education IL-33 CONTAINING MATRIX-BONDED VESICLES (MBVS) AND THEIR USE
JP2021527518A (ja) * 2018-06-21 2021-10-14 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 食道粘膜下流体クッションとしての膀胱ｅｃｍヒドロゲルの使用
JP2021529024A (ja) * 2018-06-21 2021-10-28 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 食道粘膜下流体クッションとしての細胞外マトリックス（ｅｃｍ）ヒドロゲルの使用
ES2966711T3 (es) * 2018-06-21 2024-04-23 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel de matriz extracelular (ECM) como almohadilla líquida submucosa
KR20210142003A (ko) 2019-03-13 2021-11-23 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 음향 세포외 기질 하이드로겔 및 이의 용도
WO2021174085A1 (en) 2020-02-28 2021-09-02 Texas Medical Center Sprayable stimuli-responsive micro-hydrogels for adhesion prevention and enhanced tissue healing
US20230374465A1 (en) * 2020-11-17 2023-11-23 Cellartgen Inc. Esophagus extracellular matrix-derived scaffold for culture and transplantation of esophageal organoid, and method of preparing the same

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Also Published As

Publication number Publication date
EP4252842B1 (en) 2025-06-25
WO2018161028A1 (en) 2018-09-07
US20240189349A1 (en) 2024-06-13
KR20190120258A (ko) 2019-10-23
US11213545B2 (en) 2022-01-04
EP4252842A2 (en) 2023-10-04
KR102745611B1 (ko) 2024-12-20
CN110352061A (zh) 2019-10-18
US20200009187A1 (en) 2020-01-09
JP2023024578A (ja) 2023-02-16
CA3052489A1 (en) 2018-09-07
EP3589292A4 (en) 2020-12-09
AU2024200617A1 (en) 2024-02-22
US20220249549A1 (en) 2022-08-11
JP7203428B2 (ja) 2023-01-13
JP2020509048A (ja) 2020-03-26
EP3589292B1 (en) 2023-08-23
EP4252842A3 (en) 2023-10-25
ES3039679T3 (en) 2025-10-23
AU2024200617B2 (en) 2025-10-23
JP2025019254A (ja) 2025-02-06
AU2018226867A1 (en) 2019-08-22
ES2957291T3 (es) 2024-01-16
US12303533B2 (en) 2025-05-20
EP3589292A1 (en) 2020-01-08
JP7681909B2 (ja) 2025-05-23
US11707485B2 (en) 2023-07-25

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