AU2017359172A1 - IL-2 variants for the treatment of autoimmune diseases - Google Patents
IL-2 variants for the treatment of autoimmune diseases Download PDFInfo
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- AU2017359172A1 AU2017359172A1 AU2017359172A AU2017359172A AU2017359172A1 AU 2017359172 A1 AU2017359172 A1 AU 2017359172A1 AU 2017359172 A AU2017359172 A AU 2017359172A AU 2017359172 A AU2017359172 A AU 2017359172A AU 2017359172 A1 AU2017359172 A1 AU 2017359172A1
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| SI2665486T1 (sl) | 2011-01-18 | 2020-07-31 | Bioniz, Llc | Sestavki za moduliranje aktivnosti gama-C-citokina |
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| JP7165717B2 (ja) | 2017-03-15 | 2022-11-04 | パンディオン・オペレーションズ・インコーポレイテッド | 標的免疫寛容 |
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| WO2019104092A1 (en) | 2017-11-21 | 2019-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| MX2020006322A (es) | 2017-12-19 | 2020-09-18 | Xencor Inc | Proteinas de fusion il-2 fc modificadas. |
| AU2019233581B2 (en) | 2018-03-13 | 2025-08-28 | Cancer Research Technology Limited | Anti-CD25 for tumour specific cell depletion |
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| WO2019246404A1 (en) | 2018-06-22 | 2019-12-26 | Cugene Inc. | Interleukin-2 variants and methods of uses thereof |
| WO2020007937A1 (en) * | 2018-07-03 | 2020-01-09 | Iltoo Pharma | Use of interleukin-2 for treating systemic sclerosis |
| CA3108865A1 (en) | 2018-08-06 | 2020-02-13 | Medikine, Inc. | Il-2 receptor binding compounds |
| WO2020130300A1 (ko) * | 2018-12-21 | 2020-06-25 | 한미약품 주식회사 | 신규 면역 억제 인터루킨 2 |
| WO2020227019A1 (en) * | 2019-05-03 | 2020-11-12 | Bioniz, Llc | Modulating the effects of gamma-c-cytokine signaling for the treatment of alopecia and alopecia associated disorders |
| EP3972992A4 (en) | 2019-05-20 | 2023-07-19 | Pandion Operations, Inc. | MADCAM TARGETED IMMUNOTLERANCE |
| PH12022550165A1 (en) | 2019-07-26 | 2023-05-08 | Visterra Inc | Interleukin-2 agents and uses thereof |
| CN114853874B (zh) * | 2019-09-10 | 2024-05-17 | 中国医学科学院北京协和医院 | 靶向调节t细胞的长效白介素-2及其在治疗自身免疫病中的应用 |
| AU2020378282B2 (en) | 2019-11-05 | 2023-05-18 | Medikine, Inc. | Dual IL-2R and IL-7R binding compounds |
| JP7427286B2 (ja) | 2019-11-05 | 2024-02-05 | メディカイン、インコーポレイテッド | ＩＬ－２ＲβγＣ結合化合物 |
| US20210188934A1 (en) | 2019-12-20 | 2021-06-24 | Regeneron Pharmaceuticals, Inc. | Novel il2 agonists and methods of use thereof |
| WO2021140416A2 (en) | 2020-01-10 | 2021-07-15 | Bright Peak Therapeutics Ag | Modified il-2 polypeptides and uses thereof |
| AU2021207661A1 (en) * | 2020-01-14 | 2022-07-21 | Synthekine, Inc. | IL2 muteins |
| US11491205B2 (en) | 2020-01-14 | 2022-11-08 | Synthekine, Inc. | Biased IL2 muteins methods and compositions |
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| JP2023512687A (ja) | 2020-02-03 | 2023-03-28 | メディカイン、インコーポレイテッド | ＩＬ－７Ｒα結合化合物 |
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| EP4304624A4 (en) * | 2021-03-11 | 2025-02-19 | The Methodist Hospital | METHODS AND COMPOSITIONS FOR THE TREATING OF DISEASES |
| IL304365B2 (en) * | 2021-03-31 | 2025-04-01 | Hanmi Pharmaceutical Co Ltd | A novel conjugate of an IL2 immunostimulatory analog and method of preparation thereof |
| KR20240021155A (ko) * | 2021-04-16 | 2024-02-16 | 오리오니스 바이오사이언시즈 인코포레이티드 | Il-2 기반 작제물 |
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2017
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- 2017-11-08 JP JP2019523626A patent/JP2019532996A/ja active Pending
- 2017-11-08 KR KR1020197016263A patent/KR20190083656A/ko not_active Ceased
- 2017-11-08 SG SG11201903882VA patent/SG11201903882VA/en unknown
- 2017-11-08 EP EP17869254.7A patent/EP3538548A4/en not_active Withdrawn
- 2017-11-08 EA EA201991142A patent/EA201991142A1/ru unknown
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- 2017-11-08 WO PCT/US2017/060534 patent/WO2018089420A1/en not_active Ceased
- 2017-11-08 US US15/806,787 patent/US11077172B2/en not_active Expired - Fee Related
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2019
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2021
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| IL266178A (en) | 2019-06-30 |
| CO2019005922A2 (es) | 2019-08-30 |
| MX2019005400A (es) | 2019-08-05 |
| EP3538548A4 (en) | 2020-08-19 |
| KR20190083656A (ko) | 2019-07-12 |
| US11077172B2 (en) | 2021-08-03 |
| SG11201903882VA (en) | 2019-05-30 |
| CL2019001265A1 (es) | 2019-10-04 |
| JP2022119829A (ja) | 2022-08-17 |
| CA3041334A1 (en) | 2018-05-17 |
| EA201991142A1 (ru) | 2019-10-31 |
| US20180125941A1 (en) | 2018-05-10 |
| JP2019532996A (ja) | 2019-11-14 |
| EP3538548A1 (en) | 2019-09-18 |
| WO2018089420A1 (en) | 2018-05-17 |
| ECSP19041447A (es) | 2019-07-31 |
| US20210308222A1 (en) | 2021-10-07 |
| CN110167957A (zh) | 2019-08-23 |
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