AU2017357944B2 - Activin receptor type IIa variants and methods of use thereof - Google Patents

Activin receptor type IIa variants and methods of use thereof Download PDF

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AU2017357944B2
AU2017357944B2 AU2017357944A AU2017357944A AU2017357944B2 AU 2017357944 B2 AU2017357944 B2 AU 2017357944B2 AU 2017357944 A AU2017357944 A AU 2017357944A AU 2017357944 A AU2017357944 A AU 2017357944A AU 2017357944 B2 AU2017357944 B2 AU 2017357944B2
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AU2017357944A1 (en
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Jennifer Lachey
Jasbir S. Seehra
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Keros Therapeutics Inc
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
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    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
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    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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AU2017357944A 2016-11-10 2017-11-09 Activin receptor type IIa variants and methods of use thereof Active AU2017357944B2 (en)

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US201662420476P 2016-11-10 2016-11-10
US62/420,476 2016-11-10
US201762531943P 2017-07-13 2017-07-13
US62/531,943 2017-07-13
PCT/US2017/060970 WO2018089715A1 (en) 2016-11-10 2017-11-09 Activin receptor type iia variants and methods of use thereof

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AU2017357944B2 true AU2017357944B2 (en) 2024-11-14

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US (5) US11013785B2 (enExample)
EP (2) EP3538128A4 (enExample)
JP (5) JP7051846B2 (enExample)
CN (5) CN119569850A (enExample)
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CA (2) CA3043184A1 (enExample)
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