AU2017334035B2 - Treatment of prostate cancer - Google Patents

Treatment of prostate cancer Download PDF

Info

Publication number
AU2017334035B2
AU2017334035B2 AU2017334035A AU2017334035A AU2017334035B2 AU 2017334035 B2 AU2017334035 B2 AU 2017334035B2 AU 2017334035 A AU2017334035 A AU 2017334035A AU 2017334035 A AU2017334035 A AU 2017334035A AU 2017334035 B2 AU2017334035 B2 AU 2017334035B2
Authority
AU
Australia
Prior art keywords
oral
administration
once
disclosure
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2017334035A
Other languages
English (en)
Other versions
AU2017334035A1 (en
Inventor
Brendan Mark JOHNSON
David B. Maclean
Paul N. Mudd Jr.
Vijaykumar Reddy RAJASEKHAR
Lynn Seely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Takeda Pharmaceutical Co Ltd
Sumitomo Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2017334035(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharmaceuticals Co Ltd, Takeda Pharmaceutical Co Ltd, Sumitomo Pharma Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of AU2017334035A1 publication Critical patent/AU2017334035A1/en
Application granted granted Critical
Publication of AU2017334035B2 publication Critical patent/AU2017334035B2/en
Priority to AU2023201047A priority Critical patent/AU2023201047B2/en
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED, SUMITOMO PHARMA SWITZERLAND GMBH reassignment TAKEDA PHARMACEUTICAL COMPANY LIMITED Request to Amend Deed and Register Assignors: MYOVANT SCIENCES GMBH, TAKEDA PHARMACEUTICAL COMPANY LIMITED
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED, SUMITOMO PHARMA CO., LTD reassignment TAKEDA PHARMACEUTICAL COMPANY LIMITED Request for Assignment Assignors: SUMITOMO PHARMA SWITZERLAND GMBH, TAKEDA PHARMACEUTICAL COMPANY LIMITED
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU2017334035A 2016-09-30 2017-09-29 Treatment of prostate cancer Active AU2017334035B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023201047A AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662402004P 2016-09-30 2016-09-30
US201662402150P 2016-09-30 2016-09-30
US62/402,004 2016-09-30
US62/402,150 2016-09-30
PCT/EP2017/074849 WO2018060463A2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023201047A Division AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Publications (2)

Publication Number Publication Date
AU2017334035A1 AU2017334035A1 (en) 2019-05-16
AU2017334035B2 true AU2017334035B2 (en) 2022-11-24

Family

ID=60915459

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017334035A Active AU2017334035B2 (en) 2016-09-30 2017-09-29 Treatment of prostate cancer
AU2023201047A Active AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2023201047A Active AU2023201047B2 (en) 2016-09-30 2023-02-22 Treatment of prostate cancer

Country Status (21)

Country Link
US (8) US10449191B2 (https=)
EP (2) EP3518932B1 (https=)
JP (1) JP7062673B2 (https=)
CN (1) CN110248661A (https=)
AU (2) AU2017334035B2 (https=)
BR (1) BR112019006228A2 (https=)
CA (1) CA3038875A1 (https=)
DK (1) DK3518932T3 (https=)
ES (1) ES3002857T3 (https=)
FI (1) FI3518932T3 (https=)
HR (1) HRP20241740T1 (https=)
HU (1) HUE070578T2 (https=)
IL (3) IL300071A (https=)
LT (1) LT3518932T (https=)
MA (1) MA46361A (https=)
MX (2) MX2019003733A (https=)
NZ (1) NZ752918A (https=)
PL (1) PL3518932T3 (https=)
PT (1) PT3518932T (https=)
SI (1) SI3518932T1 (https=)
WO (1) WO2018060463A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR092707A1 (es) 2012-09-28 2015-04-29 Takeda Pharmaceuticals Co Metodo de produccion de derivado de tienopirimidina
ES2912929T5 (en) 2016-09-30 2025-05-09 Sumitomo Pharma Switzerland Gmbh Methods of treating uterine fibroids and endometriosis
MA46361A (fr) 2016-09-30 2021-03-31 Myovant Sciences Gmbh Traitement du cancer de la prostate
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
WO2021069700A1 (en) * 2019-10-10 2021-04-15 Myovant Sciences Gmbh Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
JP2022551316A (ja) 2019-10-10 2022-12-08 ミオバント サイエンシズ ゲーエムベーハー Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形
CA3185151A1 (en) 2020-05-29 2021-12-02 Myovant Sciences Gmbh Combination solid oral dosage forms of gonadotropin-releasing hormone antagonists
US20230384316A1 (en) * 2020-10-20 2023-11-30 Baylor College Of Medicine Multiplex metabolic markers in plasma for early detection of african american prostate cancer
WO2022101303A1 (en) 2020-11-11 2022-05-19 Myovant Sciences Gmbh Methods of administering relugolix
JP2024540922A (ja) 2021-10-18 2024-11-06 スミトモ ファーマ スウィッツァーランド ゲーエムベーハー Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素のエタノール溶媒和物の結晶形
WO2023152611A1 (en) * 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
US6297379B1 (en) 1999-03-24 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
US6849738B2 (en) 2000-02-29 2005-02-01 Takeda Chemical Industries, Ltd. Processes for the production of thienopyrimidine derivatives
US20050043315A1 (en) 2002-01-02 2005-02-24 Hideo Tsutsumi Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them
WO2003064429A1 (en) 2002-01-30 2003-08-07 Takeda Chemical Industries, Ltd. Thienopyrimidines, process for preparing the same and use thereof
KR20100090726A (ko) 2002-02-26 2010-08-16 아스트라제네카 아베 수용성 셀룰로스 유도체를 포함하는 이레사의 약학 조제물
US7300935B2 (en) 2003-01-29 2007-11-27 Takeda Pharmaceutical Company Thienopyrimidine compounds and use thereof
CN100424078C (zh) 2003-07-07 2008-10-08 纽罗克里生物科学有限公司 作为促性激素释放激素受体拮抗剂的嘧啶-2,4-二酮衍生物
ES2494842T3 (es) 2005-07-22 2014-09-16 Takeda Pharmaceutical Company Limited Agente que previene la ovulación precoz
PE20090044A1 (es) 2007-04-06 2009-01-23 Neurocrine Biosciences Inc Antagonistas del receptor de la hormona liberadora de gonadotropina y procedimientos relacionados con los mismos
US8765948B2 (en) 2007-11-07 2014-07-01 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
TWI442932B (zh) 2008-02-11 2014-07-01 Ferring Int Ct Sa 以ＧｎＲＨ拮抗劑治療攝護腺癌的方法
WO2010026993A1 (ja) 2008-09-03 2010-03-11 武田薬品工業株式会社 製剤における吸収性改善方法および吸収性が改善された製剤
AR092707A1 (es) 2012-09-28 2015-04-29 Takeda Pharmaceuticals Co Metodo de produccion de derivado de tienopirimidina
EP3185881B1 (en) 2014-08-26 2022-03-09 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
TWI744224B (zh) 2015-02-26 2021-11-01 日商武田藥品工業股份有限公司 固形製劑
AU2016317955B2 (en) 2015-09-01 2021-05-20 Abbvie Inc. Methods of administering Elagolix
US20180044977A1 (en) 2016-08-12 2018-02-15 Raynor Mfg. Co. Rolling door construction for controlling air leakage
ES2912929T5 (en) 2016-09-30 2025-05-09 Sumitomo Pharma Switzerland Gmbh Methods of treating uterine fibroids and endometriosis
MA46361A (fr) 2016-09-30 2021-03-31 Myovant Sciences Gmbh Traitement du cancer de la prostate

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NCT02135445 ClinicalTrials.gov Archive, 2 June 2016 *
SHORE NEAL D ET AL: "PD28-01", JOURNAL OF UROLOGY, vol. 195(4S) page e654 (2016-05-08) *

Also Published As

Publication number Publication date
US20200129507A1 (en) 2020-04-30
US12336990B2 (en) 2025-06-24
EP3518932B1 (en) 2024-11-13
US20250082632A1 (en) 2025-03-13
IL265697A (en) 2019-05-30
NZ752918A (en) 2022-09-30
JP7062673B2 (ja) 2022-05-06
MX2023001468A (es) 2023-03-03
ES3002857T3 (en) 2025-03-07
LT3518932T (lt) 2025-02-10
PT3518932T (pt) 2025-01-16
MA46361A (fr) 2021-03-31
US20250057839A1 (en) 2025-02-20
CN110248661A (zh) 2019-09-17
IL265697B1 (en) 2023-03-01
HRP20241740T1 (hr) 2025-02-28
US12097198B2 (en) 2024-09-24
WO2018060463A2 (en) 2018-04-05
FI3518932T3 (fi) 2025-02-03
US11583526B2 (en) 2023-02-21
US20210205303A1 (en) 2021-07-08
PL3518932T3 (pl) 2025-04-07
US10449191B2 (en) 2019-10-22
US20240358700A1 (en) 2024-10-31
US20220401443A1 (en) 2022-12-22
HUE070578T2 (hu) 2025-06-28
IL300071A (en) 2023-03-01
WO2018060463A3 (en) 2018-05-11
DK3518932T3 (da) 2025-01-27
JP2019529574A (ja) 2019-10-17
EP4520398A3 (en) 2025-04-02
MX2019003733A (es) 2019-09-26
IL308528A (en) 2024-01-01
BR112019006228A2 (pt) 2019-06-18
AU2023201047A1 (en) 2023-03-23
AU2017334035A1 (en) 2019-05-16
EP4520398A2 (en) 2025-03-12
US12144809B1 (en) 2024-11-19
US20250332166A1 (en) 2025-10-30
IL265697B2 (en) 2023-07-01
AU2023201047B2 (en) 2025-04-03
CA3038875A1 (en) 2018-04-05
EP3518932A2 (en) 2019-08-07
US20190224196A1 (en) 2019-07-25
US10786501B2 (en) 2020-09-29
SI3518932T1 (sl) 2025-03-31

Similar Documents

Publication Publication Date Title
AU2023201047B2 (en) Treatment of prostate cancer
AU2022241582C1 (en) Methods of treating uterine fibroids and endometriosis
WO2001078686A1 (en) Time-release coated solid compositions for oral administration
JP2023096079A (ja) 化合物の製剤およびそれらの使用
HK40012835A (en) Treatment of prostate cancer
HK40012835B (en) Treatment of prostate cancer
HK40116485A (en) Treatment of prostate cancer
CN100589806C (zh) 类固醇衍生物在制备治疗血管紧张素ⅱ相关性疾病如心血管性和增生性疾病的药物中的应用
JPWO2009081837A1 (ja) 下部尿路症状の改善用医薬組成物
EA043716B1 (ru) Лечение рака предстательной железы
JP2023541423A (ja) Ｆｘｒアゴニストの固体分散体製剤
HK40012837B (en) Methods of treating uterine fibroids and endometriosis

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: SUMITOMO PHARMA SWITZERLAND GMBH

Free format text: FORMER NAME(S): TAKEDA PHARMACEUTICAL COMPANY LIMITED; MYOVANT SCIENCES GMBH

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Free format text: FORMER NAME(S): TAKEDA PHARMACEUTICAL COMPANY LIMITED; MYOVANT SCIENCES GMBH

PC Assignment registered

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Free format text: FORMER OWNER(S): SUMITOMO PHARMA SWITZERLAND GMBH; TAKEDA PHARMACEUTICAL COMPANY LIMITED

Owner name: SUMITOMO PHARMA CO., LTD

Free format text: FORMER OWNER(S): SUMITOMO PHARMA SWITZERLAND GMBH; TAKEDA PHARMACEUTICAL COMPANY LIMITED