AU2016366677A1 - Compositions and methods for treatment of HER2 positive metastatic breast cancer - Google Patents
Compositions and methods for treatment of HER2 positive metastatic breast cancer Download PDFInfo
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- AU2016366677A1 AU2016366677A1 AU2016366677A AU2016366677A AU2016366677A1 AU 2016366677 A1 AU2016366677 A1 AU 2016366677A1 AU 2016366677 A AU2016366677 A AU 2016366677A AU 2016366677 A AU2016366677 A AU 2016366677A AU 2016366677 A1 AU2016366677 A1 AU 2016366677A1
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
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- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201562265382P | 2015-12-09 | 2015-12-09 | |
| US62/265,382 | 2015-12-09 | ||
| PCT/US2016/066018 WO2017100709A1 (fr) | 2015-12-09 | 2016-12-09 | Compositions et méthodes pour le traitement du cancer du sein métastatique her2-positif |
Publications (1)
| Publication Number | Publication Date |
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| AU2016366677A1 true AU2016366677A1 (en) | 2018-07-26 |
Family
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Family Applications (1)
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| AU2016366677A Abandoned AU2016366677A1 (en) | 2015-12-09 | 2016-12-09 | Compositions and methods for treatment of HER2 positive metastatic breast cancer |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180360881A1 (fr) |
| EP (1) | EP3386522A4 (fr) |
| JP (1) | JP2018537536A (fr) |
| KR (1) | KR20180123214A (fr) |
| CN (1) | CN109475576A (fr) |
| AU (1) | AU2016366677A1 (fr) |
| CA (1) | CA3007996A1 (fr) |
| WO (1) | WO2017100709A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7158104B2 (ja) * | 2016-07-15 | 2022-10-21 | ビラクタ セラピューティクス，インク． | Ｎｋ細胞ベースの療法で使用するためのｈｄａｃ阻害剤 |
| EP3641890A4 (fr) * | 2017-06-22 | 2021-01-13 | University of Southern California | Polythérapie anticancéreuse utilisant des cellules tueuses naturelles manipulées à récepteur antigénique chimérique en tant que supports de médicament chimiothérapeutique |
| WO2019036485A1 (fr) * | 2017-08-15 | 2019-02-21 | Nantcell, Inc. | Associations de cétuximab et de cellules tueuses naturelles à affinité élevée et méthodes associées |
| CN110484507B (zh) * | 2018-01-31 | 2023-10-13 | 温州医科大学 | 一种靶向肿瘤Her2的新型嵌合抗原受体T细胞的制备技术 |
| IL278857B1 (en) * | 2018-05-22 | 2024-05-01 | Immunitybio Inc | Recombinant NK cells expressing a chimeric antigen receptor (CAR) for EPSILON–FC and uses thereof |
| BR112021001750A2 (pt) * | 2018-08-06 | 2021-04-27 | Daiichi Sankyo Company, Limited | composição farmacêutica |
| CA3094111C (fr) | 2018-10-31 | 2024-02-20 | Nantkwest, Inc. | Elimination de malignites positives pour pd-l1 par des cellules nk exprimant un recepteur d'antigene chimerique pd-l1 |
| AU2020320187B2 (en) * | 2019-07-26 | 2024-04-18 | Nantkwest, Inc. | Antibody pre-loaded CD16+NK-92 cells as an effective therapeutic product for tumor lysis |
| JP2023532852A (ja) | 2020-07-07 | 2023-08-01 | キャンキュア， エルエルシー | Ｍｉｃ抗体及び結合剤ならびにそれらの使用方法 |
| CN112675313A (zh) * | 2020-12-28 | 2021-04-20 | 烟台大学 | 连接曲妥珠单抗片段的美登素纳米粒组合物 |
| CN114807237A (zh) * | 2022-05-12 | 2022-07-29 | 广东普罗凯融生物医药科技有限公司 | 一种过表达CD16a的NK细胞的制备方法及其应用 |
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| AU2003213231A1 (en) * | 2002-02-25 | 2003-09-09 | Elan Pharmaceuticals, Inc. | Administration of agents for the treatment of inflammation |
| PT1836225E (pt) * | 2005-01-06 | 2012-01-10 | Novo Nordisk As | Agentes de ligação a kir e métodos de utilização dos mesmos |
| WO2006113665A2 (fr) * | 2005-04-15 | 2006-10-26 | Macrogenics, Inc. | Di-anticorps covalents et leurs utilisations |
| EP2161339A1 (fr) * | 2008-08-29 | 2010-03-10 | F. Hoffmann-La Roche Ag | ADCC dotée de cellules NK92 modifiées |
| EP3062800B1 (fr) * | 2013-11-01 | 2020-04-08 | Nantkwest, Inc. | Compositions tumoricides |
| EP4227318A1 (fr) * | 2014-03-28 | 2023-08-16 | Regents of the University of Minnesota | Polypeptides, cellules et procédés impliquant cd16 génétiquement modifié |
| EP3273977A4 (fr) * | 2015-03-27 | 2018-12-05 | Nantkwest, Inc. | Cellules nk-92 utilisées dans une polythérapie en association avec des médicaments anticancéreux |
-
2016
- 2016-12-09 US US15/781,428 patent/US20180360881A1/en not_active Abandoned
- 2016-12-09 CN CN201680080518.8A patent/CN109475576A/zh active Pending
- 2016-12-09 AU AU2016366677A patent/AU2016366677A1/en not_active Abandoned
- 2016-12-09 KR KR1020187019391A patent/KR20180123214A/ko not_active Application Discontinuation
- 2016-12-09 EP EP16874010.8A patent/EP3386522A4/fr not_active Withdrawn
- 2016-12-09 WO PCT/US2016/066018 patent/WO2017100709A1/fr active Application Filing
- 2016-12-09 JP JP2018549407A patent/JP2018537536A/ja active Pending
- 2016-12-09 CA CA3007996A patent/CA3007996A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20180123214A (ko) | 2018-11-15 |
| JP2018537536A (ja) | 2018-12-20 |
| EP3386522A4 (fr) | 2019-06-19 |
| EP3386522A1 (fr) | 2018-10-17 |
| CA3007996A1 (fr) | 2017-06-15 |
| US20180360881A1 (en) | 2018-12-20 |
| WO2017100709A1 (fr) | 2017-06-15 |
| CN109475576A (zh) | 2019-03-15 |
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