AU2016357567B2 - Media and fermentation methods for producing polysaccharides in bacterial cell culture - Google Patents

Media and fermentation methods for producing polysaccharides in bacterial cell culture Download PDF

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Publication number
AU2016357567B2
AU2016357567B2 AU2016357567A AU2016357567A AU2016357567B2 AU 2016357567 B2 AU2016357567 B2 AU 2016357567B2 AU 2016357567 A AU2016357567 A AU 2016357567A AU 2016357567 A AU2016357567 A AU 2016357567A AU 2016357567 B2 AU2016357567 B2 AU 2016357567B2
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medium
polysaccharide
concentration
vvh
perfusion
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AU2016357567A1 (en
Inventor
Sunil Gururao DESAI
Michael Allen Hanson
Jonathan Patrick KINROSS
Daniel R. Lasko
Scott Ellis LOMBERK
Jason Arnold Lotvin
Sujata Kaushikbhai PATEL-BROWN
Weiqiang SUN
Peter Anthony TOMASELLO
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Pfizer Corp SRL
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Pfizer Corp Belgium
Pfizer Corp SRL
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2016357567A 2015-11-17 2016-11-10 Media and fermentation methods for producing polysaccharides in bacterial cell culture Active AU2016357567B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562256347P 2015-11-17 2015-11-17
US62/256,347 2015-11-17
US201662413051P 2016-10-26 2016-10-26
US62/413,051 2016-10-26
PCT/IB2016/056780 WO2017085602A1 (en) 2015-11-17 2016-11-10 Media and fermentation methods for producing polysaccharides in bacterial cell culture

Publications (2)

Publication Number Publication Date
AU2016357567A1 AU2016357567A1 (en) 2018-05-17
AU2016357567B2 true AU2016357567B2 (en) 2020-05-07

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Family Applications (1)

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AU2016357567A Active AU2016357567B2 (en) 2015-11-17 2016-11-10 Media and fermentation methods for producing polysaccharides in bacterial cell culture

Country Status (13)

Country Link
US (2) US10947494B2 (enExample)
EP (1) EP3377613A1 (enExample)
JP (3) JP7311966B2 (enExample)
KR (1) KR102069988B1 (enExample)
CN (1) CN108473945A (enExample)
AU (1) AU2016357567B2 (enExample)
BR (1) BR112018008864A8 (enExample)
CA (2) CA3138763A1 (enExample)
HK (1) HK1259103A1 (enExample)
IL (2) IL319202A (enExample)
MX (2) MX385736B (enExample)
RU (2) RU2021135165A (enExample)
WO (1) WO2017085602A1 (enExample)

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LT2837680T (lt) 2011-07-01 2020-07-10 Amgen Inc. Žinduolių ląstelių kultūra
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
WO2018045286A1 (en) 2016-09-02 2018-03-08 Sanofi Pasteur, Inc. Neisseria meningitidis vaccine
EP3576784B1 (en) 2017-01-31 2025-09-24 Merck Sharp & Dohme LLC Methods for making polysaccharide-protein conjugates
MX2019009867A (es) 2017-02-24 2019-10-02 Merck Sharp & Dohme Inmunogenicidad mejorada de conjugados de polisacarido-proteina de streptococcus pneumoniae.
MX394768B (es) 2017-09-07 2025-03-21 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina.
WO2019050816A1 (en) 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. ANTI-PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC CONJUGATES POLYSACCHARIDE-PROTEIN CARRIER
MX2020005779A (es) 2017-12-06 2020-10-28 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y metodos de uso de estos.
US20210252125A1 (en) 2018-04-30 2021-08-19 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
US11896656B2 (en) 2018-04-30 2024-02-13 Merck Sharp & Dohme Llc Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
EP3787674A4 (en) 2018-04-30 2022-01-26 Merck Sharp & Dohme Corp. PROCESS FOR THE PRODUCTION OF STREPTOCOCCUS PNEUMONIAE POLYSACCHARIDE CAPSULAR PROTEIN CONJUGATES FROM LYOSPHERES
WO2020117949A1 (en) * 2018-12-06 2020-06-11 Inventprise, Llc Bacterial growth on non-animal derived media
EP3876953A4 (en) * 2018-12-11 2022-10-19 ERBI Biosystems, Inc. PROCESS FOR MANUFACTURING CELL-BASED PRODUCTS USING SMALL VOLUME PERFUSION PROCESSES
AU2019401535B2 (en) 2018-12-19 2023-12-14 Merck Sharp & Dohme Llc Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
CN111254103B (zh) * 2019-11-19 2023-06-02 河南省生物工程技术研究中心 一种非洲猪瘟基因工程疫苗高密度发酵补料培养基及发酵工艺
DK4138771T3 (da) * 2020-04-20 2024-05-27 Evonik Operations Gmbh Sammensætninger, som omfatter cys-peptidr
CN114015622A (zh) * 2021-12-14 2022-02-08 塔里木大学 无乳链球菌培养基及其制备方法
JP2025501499A (ja) * 2022-01-05 2025-01-22 ノルドマルク ファーマ ゲーエムベーハー Hathewaya histolytica(またはclostridium histolyticum)を増殖させるための、および1種または複数のプロテアーゼの産生のための培養培地
CN114181872B (zh) * 2022-01-07 2023-11-24 北京大北农科技集团股份有限公司 一种屎肠球菌高密度发酵培养方法
KR102866798B1 (ko) * 2022-12-27 2025-10-01 (주)진성유니텍 살모넬라균 증균을 위한 최소배지 및 이를 이용한 살모넬라균 증균방법
KR102864280B1 (ko) * 2022-12-27 2025-09-26 (주)진성유니텍 포도상구균 증균을 위한 최소배지 및 이를 이용한 포도상구균 증균방법
CN117821342B (zh) * 2024-02-29 2024-06-04 北京民海生物科技有限公司 一种14型肺炎链球菌的发酵方法
KR102894728B1 (ko) 2024-11-27 2025-12-08 한국콜마주식회사 피지 생성 억제 효능, 모공 개선 효능 및 피부 장벽 강화 효능이 우수한 흑효모 발효물 및 이의 제조방법

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WO2003012058A2 (en) * 2001-08-02 2003-02-13 North Carolina State University Media and methods for cultivation of microorganisms
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WO2003012058A2 (en) * 2001-08-02 2003-02-13 North Carolina State University Media and methods for cultivation of microorganisms
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Also Published As

Publication number Publication date
RU2761633C2 (ru) 2021-12-13
IL259404A (en) 2018-07-31
CA3005308C (en) 2022-01-04
MX2018006063A (es) 2018-09-17
RU2021135165A (ru) 2021-12-29
CA3138763A1 (en) 2017-05-26
HK1259103A1 (zh) 2019-11-22
KR20180073699A (ko) 2018-07-02
JP2022017529A (ja) 2022-01-25
IL319202A (en) 2025-04-01
US20210180008A1 (en) 2021-06-17
RU2018118035A3 (enExample) 2019-12-18
IL259404B1 (en) 2025-04-01
JP7311966B2 (ja) 2023-07-20
US10947494B2 (en) 2021-03-16
CA3005308A1 (en) 2017-05-26
JP2024037949A (ja) 2024-03-19
CN108473945A (zh) 2018-08-31
WO2017085602A1 (en) 2017-05-26
KR102069988B1 (ko) 2020-01-23
RU2018118035A (ru) 2019-12-18
AU2016357567A1 (en) 2018-05-17
BR112018008864A8 (pt) 2019-02-26
JP2018533366A (ja) 2018-11-15
BR112018008864A2 (pt) 2018-11-06
US20190292513A1 (en) 2019-09-26
MX2021010518A (es) 2021-10-01
MX385736B (es) 2025-03-18
IL259404B2 (en) 2025-08-01
EP3377613A1 (en) 2018-09-26

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