AU2016298398A1 - Heavy chain only antibodies to ANG-2 - Google Patents
Heavy chain only antibodies to ANG-2 Download PDFInfo
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- AU2016298398A1 AU2016298398A1 AU2016298398A AU2016298398A AU2016298398A1 AU 2016298398 A1 AU2016298398 A1 AU 2016298398A1 AU 2016298398 A AU2016298398 A AU 2016298398A AU 2016298398 A AU2016298398 A AU 2016298398A AU 2016298398 A1 AU2016298398 A1 AU 2016298398A1
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- hcab
- antigen
- ang
- binding specificity
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2022259761A AU2022259761A1 (en) | 2015-07-29 | 2022-10-26 | Heavy chain only antibodies to ANG-2 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562198518P | 2015-07-29 | 2015-07-29 | |
| US62/198,518 | 2015-07-29 | ||
| US201562205185P | 2015-08-14 | 2015-08-14 | |
| US62/205,185 | 2015-08-14 | ||
| PCT/US2016/044838 WO2017020001A2 (en) | 2015-07-29 | 2016-07-29 | Heavy chain only antibodies to ang-2 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022259761A Division AU2022259761A1 (en) | 2015-07-29 | 2022-10-26 | Heavy chain only antibodies to ANG-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2016298398A1 true AU2016298398A1 (en) | 2018-02-08 |
Family
ID=56610025
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016298398A Abandoned AU2016298398A1 (en) | 2015-07-29 | 2016-07-29 | Heavy chain only antibodies to ANG-2 |
| AU2022259761A Abandoned AU2022259761A1 (en) | 2015-07-29 | 2022-10-26 | Heavy chain only antibodies to ANG-2 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022259761A Abandoned AU2022259761A1 (en) | 2015-07-29 | 2022-10-26 | Heavy chain only antibodies to ANG-2 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10266589B2 (enExample) |
| EP (2) | EP3792279A3 (enExample) |
| JP (1) | JP6916776B2 (enExample) |
| CN (1) | CN107849126B (enExample) |
| AU (2) | AU2016298398A1 (enExample) |
| BR (1) | BR112018001762A2 (enExample) |
| CA (1) | CA2992660A1 (enExample) |
| DK (1) | DK3328886T3 (enExample) |
| ES (1) | ES2828694T3 (enExample) |
| HU (1) | HUE051165T2 (enExample) |
| PL (1) | PL3328886T3 (enExample) |
| RU (1) | RU2749674C2 (enExample) |
| WO (1) | WO2017020001A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| CN107849126B (zh) * | 2015-07-29 | 2022-04-08 | 阿勒根公司 | 仅有重链的抗ang-2抗体 |
| AU2016307943A1 (en) * | 2015-08-14 | 2018-02-15 | Allergan, Inc. | Heavy chain only antibodies to PDGF |
| US20220185875A1 (en) * | 2019-03-18 | 2022-06-16 | Jiangsu Hengrui Medicine Co., Ltd. | Bispecific antibody specifically bound to vegf and ang2 |
| EP4240832A4 (en) * | 2020-11-04 | 2025-01-01 | Fate Therapeutics, Inc. | Engineered ipsc and immune effector cells for heterogenous tumor control |
| CN116003591B (zh) * | 2022-12-12 | 2023-09-19 | 三门峡市眼科医院 | Ang-2抗体及其应用 |
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| SG11201408538PA (en) * | 2012-07-13 | 2015-02-27 | Roche Glycart Ag | Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases |
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| JO3405B1 (ar) | 2013-01-09 | 2019-10-20 | Regeneron Pharma | الأجسام المضادة لمضاد مستقبل عامل النمو المشتق من الصفائح الدموية - بيتا واستخداماتها |
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| KR102146845B1 (ko) * | 2013-07-30 | 2020-08-21 | 삼성전자주식회사 | 앤지오포이에틴-2에 특이적으로 결합하는 항체 및 그의 용도 |
| AU2015345322A1 (en) * | 2014-11-10 | 2017-04-06 | F. Hoffmann-La Roche Ag | Anti-PDGF-B antibodies and methods of use |
| CN107849126B (zh) * | 2015-07-29 | 2022-04-08 | 阿勒根公司 | 仅有重链的抗ang-2抗体 |
| AU2016307943A1 (en) * | 2015-08-14 | 2018-02-15 | Allergan, Inc. | Heavy chain only antibodies to PDGF |
-
2016
- 2016-07-29 CN CN201680044324.2A patent/CN107849126B/zh not_active Expired - Fee Related
- 2016-07-29 WO PCT/US2016/044838 patent/WO2017020001A2/en not_active Ceased
- 2016-07-29 EP EP20187139.9A patent/EP3792279A3/en not_active Withdrawn
- 2016-07-29 RU RU2018103960A patent/RU2749674C2/ru active
- 2016-07-29 DK DK16748025.0T patent/DK3328886T3/da active
- 2016-07-29 JP JP2018504124A patent/JP6916776B2/ja not_active Expired - Fee Related
- 2016-07-29 CA CA2992660A patent/CA2992660A1/en active Pending
- 2016-07-29 US US15/223,855 patent/US10266589B2/en active Active
- 2016-07-29 ES ES16748025T patent/ES2828694T3/es active Active
- 2016-07-29 PL PL16748025T patent/PL3328886T3/pl unknown
- 2016-07-29 BR BR112018001762A patent/BR112018001762A2/pt not_active IP Right Cessation
- 2016-07-29 HU HUE16748025A patent/HUE051165T2/hu unknown
- 2016-07-29 EP EP16748025.0A patent/EP3328886B1/en active Active
- 2016-07-29 AU AU2016298398A patent/AU2016298398A1/en not_active Abandoned
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2019
- 2019-04-16 US US16/385,384 patent/US11046756B2/en not_active Expired - Fee Related
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2021
- 2021-06-28 US US17/361,180 patent/US20210324064A1/en not_active Abandoned
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2022
- 2022-10-26 AU AU2022259761A patent/AU2022259761A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3792279A3 (en) | 2021-07-07 |
| RU2018103960A (ru) | 2019-08-28 |
| DK3328886T3 (da) | 2020-11-02 |
| US20210324064A1 (en) | 2021-10-21 |
| PL3328886T3 (pl) | 2021-02-08 |
| CA2992660A1 (en) | 2017-02-02 |
| RU2749674C2 (ru) | 2021-06-16 |
| US10266589B2 (en) | 2019-04-23 |
| US20170107279A1 (en) | 2017-04-20 |
| CN107849126B (zh) | 2022-04-08 |
| JP6916776B2 (ja) | 2021-08-11 |
| WO2017020001A2 (en) | 2017-02-02 |
| AU2022259761A1 (en) | 2022-12-01 |
| EP3792279A2 (en) | 2021-03-17 |
| EP3328886A2 (en) | 2018-06-06 |
| US11046756B2 (en) | 2021-06-29 |
| JP2018527327A (ja) | 2018-09-20 |
| RU2018103960A3 (enExample) | 2020-01-16 |
| BR112018001762A2 (pt) | 2018-09-18 |
| ES2828694T3 (es) | 2021-05-27 |
| EP3328886B1 (en) | 2020-09-16 |
| WO2017020001A3 (en) | 2017-03-16 |
| HK1253947A1 (en) | 2019-07-05 |
| US20190248882A1 (en) | 2019-08-15 |
| HUE051165T2 (hu) | 2021-03-01 |
| CN107849126A (zh) | 2018-03-27 |
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