AU2016278982A1 - CRISPR/Cas9 complex for genomic editing - Google Patents

CRISPR/Cas9 complex for genomic editing Download PDF

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AU2016278982A1
AU2016278982A1 AU2016278982A AU2016278982A AU2016278982A1 AU 2016278982 A1 AU2016278982 A1 AU 2016278982A1 AU 2016278982 A AU2016278982 A AU 2016278982A AU 2016278982 A AU2016278982 A AU 2016278982A AU 2016278982 A1 AU2016278982 A1 AU 2016278982A1
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leu
asp
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gly
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Chia-Wei Chang
Lei Ding
Tim Townes
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UAB Research Foundation
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UAB Research Foundation
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • A—HUMAN NECESSITIES
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    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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AU2016278982A 2015-06-17 2016-06-17 CRISPR/Cas9 complex for genomic editing Abandoned AU2016278982A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562181138P 2015-06-17 2015-06-17
US62/181,138 2015-06-17
US201562266316P 2015-12-11 2015-12-11
US62/266,316 2015-12-11
PCT/US2016/038161 WO2016205703A1 (en) 2015-06-17 2016-06-17 Crispr/cas9 complex for genomic editing

Publications (1)

Publication Number Publication Date
AU2016278982A1 true AU2016278982A1 (en) 2018-01-18

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AU2016278982A Abandoned AU2016278982A1 (en) 2015-06-17 2016-06-17 CRISPR/Cas9 complex for genomic editing

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US (2) US11643668B2 (enExample)
EP (1) EP3310932B1 (enExample)
JP (1) JP2018518182A (enExample)
CN (1) CN107949641A (enExample)
AU (1) AU2016278982A1 (enExample)
CA (1) CA2989831A1 (enExample)
WO (1) WO2016205703A1 (enExample)
ZA (1) ZA201800026B (enExample)

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EP3310932B1 (en) 2023-08-30
US20240117380A1 (en) 2024-04-11
EP3310932A4 (en) 2019-01-02
US11643668B2 (en) 2023-05-09
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WO2016205703A1 (en) 2016-12-22
CN107949641A (zh) 2018-04-20

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