AU2016243128A1 - HLA-G as a novel target for CAR T-cell immunotherapy - Google Patents
HLA-G as a novel target for CAR T-cell immunotherapy Download PDFInfo
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562139617P | 2015-03-27 | 2015-03-27 | |
| US62/139,617 | 2015-03-27 | ||
| PCT/US2016/024361 WO2016160622A2 (en) | 2015-03-27 | 2016-03-25 | Hla-g as a novel target for car t-cell immunotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2016243128A1 true AU2016243128A1 (en) | 2017-11-02 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2016243128A Abandoned AU2016243128A1 (en) | 2015-03-27 | 2016-03-25 | HLA-G as a novel target for CAR T-cell immunotherapy |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20190119385A1 (OSRAM) |
| EP (1) | EP3274715A4 (OSRAM) |
| JP (1) | JP6843062B2 (OSRAM) |
| CN (1) | CN107533051B (OSRAM) |
| AU (1) | AU2016243128A1 (OSRAM) |
| CA (1) | CA2981166A1 (OSRAM) |
| IL (1) | IL254699A0 (OSRAM) |
| WO (1) | WO2016160622A2 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7034950B2 (ja) | 2016-06-03 | 2022-03-14 | アンヴェクティ | 抗ｈｌａ－ｇ特異的抗体 |
| TW201829463A (zh) | 2016-11-18 | 2018-08-16 | 瑞士商赫孚孟拉羅股份公司 | 抗hla-g抗體及其用途 |
| CN106632661A (zh) * | 2017-01-10 | 2017-05-10 | 天津东亚生物技术有限公司 | 利用hla‑g分子及其抗原片段制备预防肿瘤和病毒病的广谱疫苗及其应用 |
| AU2018246143B2 (en) | 2017-03-28 | 2025-06-05 | The Trustees Of The University Of Pennsylvania | Methods to protect transplanted tissue from rejection |
| GB2588249B (en) * | 2017-06-12 | 2023-01-04 | Sinai Health Sys | Allograft tolerance without the need for systemic immune suppression |
| AR114789A1 (es) | 2018-04-18 | 2020-10-14 | Hoffmann La Roche | Anticuerpos anti-hla-g y uso de los mismos |
| AR115052A1 (es) * | 2018-04-18 | 2020-11-25 | Hoffmann La Roche | Anticuerpos multiespecíficos y utilización de los mismos |
| CN109111525B (zh) * | 2018-05-24 | 2021-10-29 | 卢英 | 一种hla-g嵌合抗原受体、编码序列和表达载体以及应用 |
| WO2020010284A1 (en) * | 2018-07-04 | 2020-01-09 | Cytoimmune Therapeutics, LLC | Compositions and methods for immunotherapy targeting flt3, pd-1, and/or pd-l1 |
| AU2019328677A1 (en) | 2018-08-31 | 2021-04-01 | Invectys SA | Chimeric antigen receptors against multiple HLA-G isoforms |
| JP7429222B2 (ja) * | 2018-08-31 | 2024-02-07 | アンヴェクティ エスアー | Ｃａｒの機能を評価する方法 |
| TWI694083B (zh) * | 2018-09-17 | 2020-05-21 | 中國醫藥大學附設醫院 | 嵌合抗原受體、核酸、嵌合抗原受體表達質體、表達嵌合抗原受體細胞、其用途以及用於治療癌症之醫藥組合物 |
| CN110903399B (zh) * | 2018-09-17 | 2022-02-01 | 台湾中国医药大学附设医院 | 嵌合抗原受体、其核酸、表达质体、细胞、用途及组合物 |
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| CA3204702A1 (en) | 2020-12-17 | 2022-06-23 | F. Hoffmann-La Roche Ag | Anti-hla-g antibodies and use thereof |
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| JPH11503320A (ja) * | 1995-04-07 | 1999-03-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Ｈｌａ−ｇ検出用抗体 |
| AT411997B (de) * | 1999-09-14 | 2004-08-26 | Baxter Ag | Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate |
| EP1224465B1 (en) * | 1999-09-27 | 2005-12-21 | Clifford L. Librach | Detection of hla-g |
| SI2301965T1 (sl) * | 2002-10-16 | 2015-07-31 | Purdue Pharma L.P. | Protitelesa, ki vežejo celično- povezan CA 125 / O722P in metode uporabe le-teh |
| JP2006521810A (ja) * | 2003-03-11 | 2006-09-28 | ジェネンテック・インコーポレーテッド | 免疫関連疾患の治療のための新規組成物と方法 |
| CN1312182C (zh) * | 2004-10-26 | 2007-04-25 | 四川新创生物科技有限公司 | 抗hla－g的单克隆抗体及分泌它的杂交瘤细胞株、癌症诊断试剂盒及其应用 |
| CN101358964B (zh) * | 2007-07-31 | 2012-06-20 | 叶尚勉 | 含抗hla-g的单克隆抗体的癌症诊断试剂盒及其应用 |
| CN101493462A (zh) * | 2008-01-25 | 2009-07-29 | 广州天美生物技术有限公司 | 化学发光免疫分析检测hla-g超敏感方法 |
| CN101520458B (zh) * | 2008-02-25 | 2014-04-16 | 广州天美生物技术有限公司 | 金标免疫分析检测hla-g及其抗体的简易方法 |
| US20120177671A1 (en) * | 2009-06-18 | 2012-07-12 | Hla-G Technologies | Hla-g alpha 1 multimers and pharmaceutical uses thereof |
| EP2445934B1 (en) * | 2009-06-25 | 2014-07-16 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Multimeric polypeptides of hla-g including at least two alpha3 domains and pharmaceutical uses thereof |
| CN101967191A (zh) * | 2009-07-28 | 2011-02-09 | 广州天美生物技术有限公司 | Hla-g抗体制备方法及其在医学中的应用 |
| FR2967579B1 (fr) * | 2010-11-23 | 2013-11-22 | Ets Francais Du Sang | Utilisation d'une isoforme d'hla-g comme agent anti-resorption osseuse |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US20120196285A1 (en) * | 2011-01-31 | 2012-08-02 | Esoterix Genetic Laboratories, Llc | Methods for Enriching Microparticles or Nucleic Acids Using Binding Molecules |
| ES2816450T3 (es) * | 2012-02-22 | 2021-04-05 | Univ Pennsylvania | Uso de CAR basados en ICOS para mejorar la actividad antitumoral y la persistencia del CAR |
| EP2730588A1 (en) * | 2012-11-12 | 2014-05-14 | Intelectys | Antibodies and fragments thereof raised against the alpha-3 domain of HLA-G protein, methods and means for their preparation, and uses thereof |
| CN103756967B (zh) * | 2013-12-31 | 2018-09-21 | 卢英 | 抗hla-g的单克隆抗体偶联免疫磁珠在肿瘤细胞分选中的应用 |
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2016
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- 2016-03-25 EP EP16773875.6A patent/EP3274715A4/en not_active Withdrawn
- 2016-03-25 CA CA2981166A patent/CA2981166A1/en not_active Abandoned
- 2016-03-25 JP JP2017550494A patent/JP6843062B2/ja not_active Expired - Fee Related
- 2016-03-25 WO PCT/US2016/024361 patent/WO2016160622A2/en not_active Ceased
- 2016-03-25 CN CN201680024710.5A patent/CN107533051B/zh not_active Expired - Fee Related
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2017
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2020
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| WO2016160622A3 (en) | 2016-12-15 |
| EP3274715A2 (en) | 2018-01-31 |
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| US20240392011A1 (en) | 2024-11-28 |
| US20210070864A1 (en) | 2021-03-11 |
| CN107533051A (zh) | 2018-01-02 |
| CN107533051B (zh) | 2020-11-13 |
| CA2981166A1 (en) | 2016-10-06 |
| US20190119385A1 (en) | 2019-04-25 |
| IL254699A0 (en) | 2017-11-30 |
| JP2018511319A (ja) | 2018-04-26 |
| EP3274715A4 (en) | 2018-10-10 |
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