AU2016226087A1 - ETV2 and uses thereof - Google Patents

ETV2 and uses thereof Download PDF

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Publication number
AU2016226087A1
AU2016226087A1 AU2016226087A AU2016226087A AU2016226087A1 AU 2016226087 A1 AU2016226087 A1 AU 2016226087A1 AU 2016226087 A AU2016226087 A AU 2016226087A AU 2016226087 A AU2016226087 A AU 2016226087A AU 2016226087 A1 AU2016226087 A1 AU 2016226087A1
Authority
AU
Australia
Prior art keywords
human
etv2
human animal
blastocyst
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016226087A
Other languages
English (en)
Inventor
Daniel J. GARRY
Mary G. GARRY
Naoko KOYANO-NAKAGAWA
Tara RASMUSSEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota System
Original Assignee
University of Minnesota Twin Cities
University of Minnesota System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota Twin Cities, University of Minnesota System filed Critical University of Minnesota Twin Cities
Publication of AU2016226087A1 publication Critical patent/AU2016226087A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8778—Swine embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0604—Whole embryos; Culture medium therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A01K2267/025—Animal producing cells or organs for transplantation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2016226087A 2015-03-03 2016-03-03 ETV2 and uses thereof Abandoned AU2016226087A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562127330P 2015-03-03 2015-03-03
US62/127,330 2015-03-03
PCT/US2016/020768 WO2016141234A1 (en) 2015-03-03 2016-03-03 Etv2 and uses thereof

Publications (1)

Publication Number Publication Date
AU2016226087A1 true AU2016226087A1 (en) 2017-10-26

Family

ID=56848633

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016226087A Abandoned AU2016226087A1 (en) 2015-03-03 2016-03-03 ETV2 and uses thereof

Country Status (15)

Country Link
US (2) US11673928B2 (OSRAM)
EP (1) EP3264891A4 (OSRAM)
JP (1) JP2018506984A (OSRAM)
KR (1) KR102684690B1 (OSRAM)
CN (1) CN108024522A (OSRAM)
AU (1) AU2016226087A1 (OSRAM)
BR (1) BR112017018932A2 (OSRAM)
CA (1) CA2978457A1 (OSRAM)
CL (1) CL2017002226A1 (OSRAM)
IL (1) IL254241A0 (OSRAM)
MX (1) MX2017011345A (OSRAM)
PH (1) PH12017501589A1 (OSRAM)
RU (1) RU2017132331A (OSRAM)
SG (1) SG11201707151YA (OSRAM)
WO (1) WO2016141234A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108024522A (zh) 2015-03-03 2018-05-11 明尼苏达大学董事会 Etv2及其用途
MX2018000273A (es) 2015-06-30 2018-03-08 Univ Minnesota Musculo esqueletico humanizado.
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado
EP3576756A4 (en) * 2017-02-03 2020-12-16 Cornell University STABLE THREE-DIMENSIONAL BLOOD VESSELS AND THEIR FORMATION PROCESSES

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU721375B2 (en) 1996-01-09 2000-06-29 Regents Of The University Of California, The Porcine embryonic stem-like cells, methods of making and using the cells to produce transgenic pigs
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
CN1241210A (zh) 1996-10-11 2000-01-12 得克萨斯农业及机械体系综合大学 产生原生殖细胞和转基因动物物种的方法
WO2003034818A1 (en) * 2001-10-24 2003-05-01 Chugai Seiyaku Kabushiki Kaisha Sgrf genetically modified nonhuman animal
US20040133931A1 (en) 2003-01-08 2004-07-08 Gavin William G. Method and system for fusion and activation following nuclear transfer in reconstructed embryos
WO2003081990A2 (en) * 2002-03-22 2003-10-09 St. Jude Children's Research Hospital Improved method for generating genetically modified animals
WO2004004447A2 (en) 2002-07-03 2004-01-15 Merck & Co., Inc. Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
GB2398784B (en) 2003-02-26 2005-07-27 Babraham Inst Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal
WO2006014551A2 (en) 2004-07-06 2006-02-09 Michigan State University In vivo methods for effecting tissue specific differentiation of embryonic stem cells
WO2008086040A1 (en) 2007-01-11 2008-07-17 University Of Pittsburgh Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same
CA2675100A1 (en) * 2007-01-20 2008-07-24 Boehringer Ingelheim International Gmbh C-reactive protein (crp) knockout mouse
CN101679950A (zh) 2007-02-22 2010-03-24 国立大学法人东京大学 利用胚泡互补的器官再生法
EP2258166A4 (en) * 2008-02-22 2013-04-03 Univ Tokyo METHOD FOR PRODUCING GROUNDS FOR REPRODUCATIVE ANIMALS WITH LETAL PHENOTYPE CREATED BY GENODIMODIFICATION
US20110258715A1 (en) 2008-08-22 2011-10-20 The University Of Tokyo ORGAN REGENERATION METHOD UTILIZING iPS CELL AND BLASTOCYST COMPLEMENTATION
US20120207744A1 (en) 2009-03-19 2012-08-16 Mendlein John D Reprogramming compositions and methods of using the same
SG175880A1 (en) 2009-05-20 2011-12-29 Cardio3 Biosciences Sa Parmaceutical composition for the treatment of heart diseases.
WO2012149470A1 (en) 2011-04-27 2012-11-01 Amyris, Inc. Methods for genomic modification
SG10201805199RA (en) 2011-06-02 2018-07-30 Harvard College Methods and Uses for Ex Vivo Tissue Culture Systems
WO2013073246A1 (en) 2011-11-18 2013-05-23 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
IL221187A (en) 2012-07-30 2017-01-31 Adom Advanced Optical Tech Ltd A system to perform optical tomography in two 2D beams
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
US11377639B2 (en) 2013-11-15 2022-07-05 Wisconsin Alumni Research Foundation Lineage reprogramming to induced cardiac progenitor cells (iCPC) by defined factors
US20160029604A1 (en) * 2014-04-28 2016-02-04 Recombinetics, Inc. Multiplex gene editing
CN108024522A (zh) 2015-03-03 2018-05-11 明尼苏达大学董事会 Etv2及其用途
BR112017028608A2 (pt) 2015-06-30 2018-09-04 Univ Minnesota músculo cardíaco humanizado
MX2018000273A (es) 2015-06-30 2018-03-08 Univ Minnesota Musculo esqueletico humanizado.
EP3367785A4 (en) 2015-10-27 2019-08-14 Regents of the University of Minnesota COMPOSITIONS AND METHODS FOR CHIMERIC EMBRYO-ASSISTED ORGAN PRODUCTION
CN108125943A (zh) 2018-01-17 2018-06-08 云南省第二人民医院 前胡醇当归脂作为制备抗动脉粥样硬化药物的应用

Also Published As

Publication number Publication date
KR102684690B1 (ko) 2024-07-15
KR20170121262A (ko) 2017-11-01
SG11201707151YA (en) 2017-09-28
US20230365638A1 (en) 2023-11-16
IL254241A0 (en) 2017-10-31
JP2018506984A (ja) 2018-03-15
CL2017002226A1 (es) 2018-07-27
CN108024522A (zh) 2018-05-11
EP3264891A1 (en) 2018-01-10
CA2978457A1 (en) 2016-09-09
WO2016141234A1 (en) 2016-09-09
PH12017501589A1 (en) 2018-02-05
US11673928B2 (en) 2023-06-13
US20180037620A1 (en) 2018-02-08
MX2017011345A (es) 2018-04-24
BR112017018932A2 (pt) 2018-07-31
RU2017132331A (ru) 2019-04-03
EP3264891A4 (en) 2018-09-05

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Legal Events

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application