AU2015342990B2 - Enzymatically polymerized gelling dextrans - Google Patents
Enzymatically polymerized gelling dextrans Download PDFInfo
- Publication number
- AU2015342990B2 AU2015342990B2 AU2015342990A AU2015342990A AU2015342990B2 AU 2015342990 B2 AU2015342990 B2 AU 2015342990B2 AU 2015342990 A AU2015342990 A AU 2015342990A AU 2015342990 A AU2015342990 A AU 2015342990A AU 2015342990 B2 AU2015342990 B2 AU 2015342990B2
- Authority
- AU
- Australia
- Prior art keywords
- dextran
- composition
- seq
- reaction
- positions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
- C12P19/08—Dextran
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Materials Engineering (AREA)
- Microbiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Confectionery (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462075460P | 2014-11-05 | 2014-11-05 | |
| US62/075,460 | 2014-11-05 | ||
| PCT/US2015/059261 WO2016073732A1 (en) | 2014-11-05 | 2015-11-05 | Enzymatically polymerized gelling dextrans |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2015342990A1 AU2015342990A1 (en) | 2017-04-27 |
| AU2015342990B2 true AU2015342990B2 (en) | 2019-08-29 |
Family
ID=54697645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015342990A Ceased AU2015342990B2 (en) | 2014-11-05 | 2015-11-05 | Enzymatically polymerized gelling dextrans |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10059779B2 (enExample) |
| EP (1) | EP3215543B1 (enExample) |
| JP (1) | JP6814737B2 (enExample) |
| CN (1) | CN107074985B (enExample) |
| AU (1) | AU2015342990B2 (enExample) |
| BR (1) | BR112017008976B1 (enExample) |
| CA (1) | CA2964165A1 (enExample) |
| ES (1) | ES2784327T3 (enExample) |
| MX (1) | MX2017005784A (enExample) |
| WO (1) | WO2016073732A1 (enExample) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2964165A1 (en) * | 2014-11-05 | 2016-05-12 | E. I. Du Pont De Nemours And Company | Enzymatically polymerized gelling dextrans |
| EP3237454B1 (en) | 2014-12-22 | 2020-08-12 | DuPont Industrial Biosciences USA, LLC | Polymeric blend containing poly alpha-1,3-glucan |
| JP6963502B2 (ja) | 2015-02-06 | 2021-11-10 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | ポリα−1,3−グルカン系ポリマーのコロイド分散液 |
| CA2975289A1 (en) | 2015-04-03 | 2016-10-06 | E I Du Pont De Nemours And Company | Gelling dextran ethers |
| EP3277100B1 (en) | 2015-04-03 | 2023-09-06 | Nutrition & Biosciences USA 4, Inc. | Oxidized dextran |
| WO2016173929A1 (en) * | 2015-04-29 | 2016-11-03 | Nestec S.A. | Sugar reduction of food products |
| US10738266B2 (en) | 2015-06-01 | 2020-08-11 | Dupont Industrial Biosciences Usa, Llc | Structured liquid compositions comprising colloidal dispersions of poly alpha-1,3-glucan |
| EP3368717B1 (en) * | 2015-10-26 | 2022-12-14 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide coatings for paper |
| JP6975158B2 (ja) | 2015-10-26 | 2021-12-01 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | 水不溶性α−(1,3→グルカン)組成物 |
| WO2017079595A1 (en) | 2015-11-05 | 2017-05-11 | E. I. Du Pont De Nemours And Company | Dextran-poly alpha-1,3-glucan graft copolymers and synthesis methods thereof |
| WO2017083226A1 (en) | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| WO2017083229A1 (en) | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| JP7045313B2 (ja) | 2015-11-13 | 2022-03-31 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物 |
| US10895028B2 (en) | 2015-12-14 | 2021-01-19 | Dupont Industrial Biosciences Usa, Llc | Nonwoven glucan webs |
| BR112019001171B1 (pt) | 2016-07-22 | 2022-08-16 | Nutrition & Biosciences Usa 4, Inc | Polímero de poliuretano, composição de poliuretano, espuma de poliuretano e substrato fibroso revestido |
| FI3512955T3 (fi) | 2016-09-14 | 2023-07-18 | Nutrition & Biosciences Usa 4 Inc | Muunneltuja glukosyylitransferaaseja |
| AU2017348076B2 (en) | 2016-10-28 | 2022-02-24 | Nutrition & Biosciences USA 4, Inc. | Rubber compositions comprising polysaccharides |
| EP3541850A1 (en) | 2016-11-16 | 2019-09-25 | E. I. du Pont de Nemours and Company | Molded article comprising polysaccharide |
| US20190345267A1 (en) | 2016-11-22 | 2019-11-14 | E I Du Pont De Nemours And Company | In situ functionalization of polysaccharides and compositions thereof |
| CN110198983A (zh) | 2016-11-22 | 2019-09-03 | 纳幕尔杜邦公司 | 制造聚丙烯腈纤维的方法 |
| AU2017376773B2 (en) | 2016-12-16 | 2021-08-19 | Nutrition & Biosciences USA 4, Inc. | Amphiphilic polysaccharide derivatives and compositions comprising same |
| EP3583136B1 (en) | 2017-02-16 | 2022-08-31 | Nutrition & Biosciences USA 4, Inc. | Crosslinked dextran and crosslinked dextran-poly alpha-1,3-glucan graft copolymers |
| US10745675B2 (en) * | 2017-05-02 | 2020-08-18 | The United States Of America, As Represented By The Secretary Of Agriculture | Modified enzymes for producing increased isomelezitose |
| WO2019005927A1 (en) | 2017-06-30 | 2019-01-03 | E. I. Du Pont De Nemours And Company | POLYSACCHARIDE-ELASTOMER MIXTURE COMPOSITIONS |
| US20200262984A1 (en) | 2017-11-10 | 2020-08-20 | Dupont Industrial Biosciences Usa, Llc | Unique morphological polysaccharide |
| US11098334B2 (en) | 2017-12-14 | 2021-08-24 | Nutrition & Biosciences USA 4, Inc. | Alpha-1,3-glucan graft copolymers |
| US10808269B2 (en) | 2018-02-23 | 2020-10-20 | Danisco Us Inc | Synthesis of glucan comprising alpha-1,3 glycosidic linkages with phosphorylase enzymes |
| WO2019173580A1 (en) * | 2018-03-09 | 2019-09-12 | E. I. Du Pont De Nemours And Company | Engineered glucosyltransferases |
| EP3870616B1 (en) | 2018-10-25 | 2023-10-11 | DuPont Industrial Biosciences USA, LLC | Alpha-1,3-glucan graft copolymers |
| EP3674402A1 (en) * | 2018-12-27 | 2020-07-01 | Sant Dalmai, S.A.U. | Weissella viridescens strain and uses thereof for the synthesis of exopolysaccharides |
| CN115003805A (zh) | 2019-07-09 | 2022-09-02 | 营养与生物科学美国第四公司 | 工程化的α-1,3分支酶 |
| WO2021034561A1 (en) | 2019-08-16 | 2021-02-25 | Nutrition & Biosciences USA 4, Inc. | Flour- and meal-based food products comprising insoluble alpha-1,3-glucan |
| WO2021092228A1 (en) | 2019-11-06 | 2021-05-14 | Nutrition & Biosciences USA 4, Inc. | Highly crystalline alpha-1,3-glucan |
| WO2021158543A1 (en) | 2020-02-04 | 2021-08-12 | Nutrition & Biosciences USA 4, Inc. | Aqueous dispersions of insoluble alpha-glucan comprising alpha-1,3 glycosidic linkages |
| ES2932508T3 (es) | 2020-05-08 | 2023-01-20 | Procter & Gamble | Recipiente de producto detergente con cierre |
| EP4161972A1 (en) | 2020-06-04 | 2023-04-12 | Nutrition & Biosciences USA 4, Inc. | Dextran-alpha-glucan graft copolymers and derivatives thereof |
| WO2021252560A1 (en) | 2020-06-10 | 2021-12-16 | The Procter & Gamble Company | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
| CA3178408A1 (en) | 2020-06-10 | 2021-12-16 | Mark Robert Sivik | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
| US20210388290A1 (en) * | 2020-06-10 | 2021-12-16 | The Procter & Gamble Company | Laundry care or dish care compositions comprising poly alpha-1,6-glucan esters |
| US20210395655A1 (en) * | 2020-06-18 | 2021-12-23 | The Procter & Gamble Company | Water-soluble unit dose article comprising a polyvinylalcohol film and a cationic poly alpha-1,6-glucan ether compound |
| EP4446244B1 (en) | 2020-07-09 | 2025-08-06 | The Procter & Gamble Company | Lid for a cardboard container wherein the lid comprises a cardboard support element |
| US20240150497A1 (en) | 2021-02-19 | 2024-05-09 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide derivatives for detergent compositions |
| CN116887807A (zh) * | 2021-03-23 | 2023-10-13 | 陶氏环球技术有限责任公司 | 毛发调理制剂 |
| EP4334364A1 (en) | 2021-05-04 | 2024-03-13 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising oxidized insoluble alpha-glucan |
| WO2022235655A1 (en) | 2021-05-04 | 2022-11-10 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising insoluble alpha-glucan |
| WO2022240744A1 (en) * | 2021-05-11 | 2022-11-17 | Elementis Specialties, Inc. | Organoclay compositions having naturally derived ester quaternary ammonium ions or amide quaternary ammonium ions |
| CN113201513B (zh) * | 2021-06-22 | 2023-06-09 | 广西产研院生物制造技术研究所有限公司 | 一种耐热右旋糖酐蔗糖酶突变体及其制备方法与应用 |
| CN117616054A (zh) | 2021-07-13 | 2024-02-27 | 营养与生物科学美国4公司 | 阳离子葡聚糖酯衍生物 |
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| WO2023081341A1 (en) | 2021-11-05 | 2023-05-11 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising one cationic alpha- 1,6-glucan derivative and one alpha- 1,3-glucan |
| US20250032390A1 (en) | 2021-12-16 | 2025-01-30 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising cationic alpha-glucan ethers in aqueous polar organic solvents |
| EP4463519A1 (en) | 2022-01-12 | 2024-11-20 | Nutrition & Biosciences USA 4, Inc. | Coating compositions comprising rubber and insoluble alpha-glucan |
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| JP2025523007A (ja) | 2022-07-11 | 2025-07-17 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | 両親媒性グルカンエステル誘導体 |
| DE202022104856U1 (de) | 2022-08-29 | 2023-12-01 | Gpi Frankfurt & Augsburg Gmbh | Faltschachtel mit Klick-Laschen |
| US20240108021A1 (en) * | 2022-09-29 | 2024-04-04 | Dupont Nutrition Biosciences Aps | Modification of steviol glycosides by glucosyltransferase enzymes |
| JP2025534620A (ja) | 2022-10-14 | 2025-10-17 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド | 水、カチオン性α-1,6-グルカンエーテル、及び有機溶媒を含む組成物 |
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| EP4704802A1 (en) | 2023-05-03 | 2026-03-11 | Nutrition & Biosciences USA 4, Inc. | Controlling bacterial cell adhesion with alpha-glucan comprising alpha-1,6 glycosidic linkages |
| CN121398902A (zh) | 2023-06-30 | 2026-01-23 | 营养与生物科学美国第四公司 | 多孔α-1,3-葡聚糖组合物 |
| WO2025072419A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences Usa 1, Llc | Crosslinked alpha-glucan derivatives |
| WO2025072417A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide derivatives |
| WO2025072416A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide derivatives |
| WO2025117349A1 (en) | 2023-11-28 | 2025-06-05 | Nutrition & Biosciences USA 4, Inc. | Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages |
| WO2025198996A1 (en) | 2024-03-19 | 2025-09-25 | Danisco Us Inc. | Method for improving flavor in foodstuff |
| WO2025199079A1 (en) | 2024-03-20 | 2025-09-25 | Nutrition & Biosciences USA 4, Inc. | Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages |
| WO2026015598A2 (en) | 2024-07-11 | 2026-01-15 | International N&H Denmark Aps | Method to provide improved texture and stable sucrose levels in foodstuff with glucosyltransferase |
| WO2026024663A1 (en) | 2024-07-24 | 2026-01-29 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising alpha-glucan with alpha-1,3 glycosidic linkages |
| WO2026024922A1 (en) | 2024-07-25 | 2026-01-29 | Danisco Us Inc. | Subtilisin variants and methods of use |
| WO2026039397A1 (en) | 2024-08-13 | 2026-02-19 | Nutrition & Biosciences USA 4, Inc. | Alpha-glucan graft copolymer derivatives |
| WO2026076093A1 (en) | 2024-10-02 | 2026-04-09 | Danisco Usa Inc. | Tunable transition temperatures of engineered beta-1,3-glucan |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103992978A (zh) * | 2014-06-11 | 2014-08-20 | 南京工业大学 | 一株假肠膜明串珠菌及其联产右旋糖酐和甘露醇的方法 |
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| US4933191A (en) * | 1987-07-01 | 1990-06-12 | Microlife Technics, Inc. | Novel dextran produced by leuconostoc dextranicum |
| JPH07274991A (ja) * | 1994-04-04 | 1995-10-24 | Fujisawa Pharmaceut Co Ltd | デキストランの製造法 |
| EP0881283A1 (fr) * | 1997-05-31 | 1998-12-02 | Societe Des Produits Nestle S.A. | Production de dextrane |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| CN1353193A (zh) * | 2000-11-02 | 2002-06-12 | 杨敏 | 酶法生产右旋糖酐 |
| NZ530638A (en) * | 2001-07-20 | 2006-01-27 | Tno | Novel glucans and novel glucansucrases derived from lactic acid bacteria |
| DE60304723T2 (de) | 2002-09-09 | 2007-04-05 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | VERZWEIGTE ALPHA-GLUCANE FüR DAS GEWICHTSMANAGEMENT |
| CN1902315B (zh) | 2003-12-03 | 2012-05-02 | 明治制果药业株式会社 | 内切葡聚糖酶stce和含有内切葡聚糖酶的纤维素酶配制品 |
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| CN103013891B (zh) * | 2012-12-27 | 2014-07-09 | 光明乳业股份有限公司 | 一株肠膜明串珠菌及其胞外多糖与应用 |
| CA2964165A1 (en) * | 2014-11-05 | 2016-05-12 | E. I. Du Pont De Nemours And Company | Enzymatically polymerized gelling dextrans |
-
2015
- 2015-11-05 CA CA2964165A patent/CA2964165A1/en not_active Abandoned
- 2015-11-05 ES ES15798600T patent/ES2784327T3/es active Active
- 2015-11-05 AU AU2015342990A patent/AU2015342990B2/en not_active Ceased
- 2015-11-05 US US14/933,128 patent/US10059779B2/en active Active
- 2015-11-05 BR BR112017008976-9A patent/BR112017008976B1/pt active IP Right Grant
- 2015-11-05 EP EP15798600.1A patent/EP3215543B1/en active Active
- 2015-11-05 MX MX2017005784A patent/MX2017005784A/es active IP Right Grant
- 2015-11-05 WO PCT/US2015/059261 patent/WO2016073732A1/en not_active Ceased
- 2015-11-05 CN CN201580060302.0A patent/CN107074985B/zh not_active Expired - Fee Related
- 2015-11-05 JP JP2017543312A patent/JP6814737B2/ja active Active
-
2018
- 2018-08-24 US US16/111,514 patent/US11390692B2/en active Active
-
2022
- 2022-07-15 US US17/865,904 patent/US12173091B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103992978A (zh) * | 2014-06-11 | 2014-08-20 | 南京工业大学 | 一株假肠膜明串珠菌及其联产右旋糖酐和甘露醇的方法 |
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| BR112017008976A2 (pt) | 2018-01-30 |
| AU2015342990A1 (en) | 2017-04-27 |
| JP2017535598A (ja) | 2017-11-30 |
| US11390692B2 (en) | 2022-07-19 |
| EP3215543B1 (en) | 2020-01-08 |
| US20230235096A1 (en) | 2023-07-27 |
| MX2017005784A (es) | 2017-07-28 |
| US20180355072A1 (en) | 2018-12-13 |
| EP3215543A1 (en) | 2017-09-13 |
| CN107074985B (zh) | 2020-07-24 |
| US12173091B2 (en) | 2024-12-24 |
| CA2964165A1 (en) | 2016-05-12 |
| JP6814737B2 (ja) | 2021-01-20 |
| US20160122445A1 (en) | 2016-05-05 |
| BR112017008976B1 (pt) | 2023-02-07 |
| CN107074985A (zh) | 2017-08-18 |
| ES2784327T3 (es) | 2020-09-24 |
| WO2016073732A1 (en) | 2016-05-12 |
| US10059779B2 (en) | 2018-08-28 |
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