BR112017008976B1 - Composição e métodos de aumento da viscosidade de composições aquosas, de tratamento de material e de produção de dextrano - Google Patents
Composição e métodos de aumento da viscosidade de composições aquosas, de tratamento de material e de produção de dextrano Download PDFInfo
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- BR112017008976B1 BR112017008976B1 BR112017008976-9A BR112017008976A BR112017008976B1 BR 112017008976 B1 BR112017008976 B1 BR 112017008976B1 BR 112017008976 A BR112017008976 A BR 112017008976A BR 112017008976 B1 BR112017008976 B1 BR 112017008976B1
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- dextran
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/02—Dextran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
- C12P19/08—Dextran
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Confectionery (AREA)
- Jellies, Jams, And Syrups (AREA)
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| US201462075460P | 2014-11-05 | 2014-11-05 | |
| US62/075,460 | 2014-11-05 | ||
| PCT/US2015/059261 WO2016073732A1 (en) | 2014-11-05 | 2015-11-05 | Enzymatically polymerized gelling dextrans |
Publications (2)
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| BR112017008976A2 BR112017008976A2 (pt) | 2018-01-30 |
| BR112017008976B1 true BR112017008976B1 (pt) | 2023-02-07 |
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| US (3) | US10059779B2 (enExample) |
| EP (1) | EP3215543B1 (enExample) |
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| AU (1) | AU2015342990B2 (enExample) |
| BR (1) | BR112017008976B1 (enExample) |
| CA (1) | CA2964165A1 (enExample) |
| ES (1) | ES2784327T3 (enExample) |
| MX (1) | MX2017005784A (enExample) |
| WO (1) | WO2016073732A1 (enExample) |
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| AU2015369929B2 (en) | 2014-12-22 | 2020-08-20 | Nutrition & Biosciences USA 4, Inc. | Polymeric blend containing poly alpha-1,3-glucan |
| WO2016126685A1 (en) | 2015-02-06 | 2016-08-11 | E. I. Du Pont De Nemours And Company | Colloidal dispersions of poly alpha-1,3-glucan based polymers |
| EP3277100B1 (en) | 2015-04-03 | 2023-09-06 | Nutrition & Biosciences USA 4, Inc. | Oxidized dextran |
| CA2975289A1 (en) | 2015-04-03 | 2016-10-06 | E I Du Pont De Nemours And Company | Gelling dextran ethers |
| US11785967B2 (en) * | 2015-04-29 | 2023-10-17 | Societe Des Produits Nestle S.A. | Sugar reduction of food products |
| CN107995923B (zh) | 2015-06-01 | 2021-11-02 | 营养与生物科学美国4公司 | 包含聚α-1,3-葡聚糖的胶体分散体的结构化的液体组合物 |
| US11230812B2 (en) | 2015-10-26 | 2022-01-25 | Nutrition & Biosciences Usa 4, Inc | Polysaccharide coatings for paper |
| US10731297B2 (en) | 2015-10-26 | 2020-08-04 | Dupont Industrial Biosciences Usa, Llc | Water insoluble alpha-(1,3-glucan) composition |
| BR112018007982B1 (pt) | 2015-11-05 | 2022-03-29 | Nutrition & Biosciences Usa 4, Inc | Composição, reação enzimática e método para preparar um copolímero de enxerto |
| JP6997706B2 (ja) | 2015-11-13 | 2022-01-18 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド | 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物 |
| JP7045313B2 (ja) | 2015-11-13 | 2022-03-31 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド | 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物 |
| WO2017083229A1 (en) | 2015-11-13 | 2017-05-18 | E. I. Du Pont De Nemours And Company | Glucan fiber compositions for use in laundry care and fabric care |
| US10895028B2 (en) | 2015-12-14 | 2021-01-19 | Dupont Industrial Biosciences Usa, Llc | Nonwoven glucan webs |
| CN109563226A (zh) | 2016-07-22 | 2019-04-02 | 纳幕尔杜邦公司 | 包含多糖的聚氨酯聚合物 |
| US10301604B2 (en) | 2016-09-14 | 2019-05-28 | E I Du Pont De Nemours And Company | Engineered glucosyltransferases |
| EP3494173B1 (en) | 2016-10-28 | 2021-06-23 | Nutrition & Biosciences USA 4, Inc. | Rubber compositions comprising polysaccharides |
| EP3541850A1 (en) | 2016-11-16 | 2019-09-25 | E. I. du Pont de Nemours and Company | Molded article comprising polysaccharide |
| US20190345267A1 (en) | 2016-11-22 | 2019-11-14 | E I Du Pont De Nemours And Company | In situ functionalization of polysaccharides and compositions thereof |
| US11248314B2 (en) | 2016-11-22 | 2022-02-15 | Nutrition & Biosciences USA 4, Inc. | Process for making polyacrylonitrile fibers |
| JP7402045B2 (ja) | 2016-12-16 | 2023-12-20 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド | 両親媒性多糖誘導体及びそれを含む組成物 |
| AU2018221352B2 (en) * | 2017-02-16 | 2022-02-17 | Nutrition & Biosciences USA 4, Inc. | Crosslinked dextran and crosslinked dextran-poly alpha-1,3-glucan graft copolymers |
| US10745675B2 (en) * | 2017-05-02 | 2020-08-18 | The United States Of America, As Represented By The Secretary Of Agriculture | Modified enzymes for producing increased isomelezitose |
| KR102696644B1 (ko) | 2017-06-30 | 2024-08-22 | 뉴트리션 앤드 바이오사이언시스 유에스에이 4, 인크. | 다당류-엘라스토머 마스터배치 조성물 |
| US20200262984A1 (en) | 2017-11-10 | 2020-08-20 | Dupont Industrial Biosciences Usa, Llc | Unique morphological polysaccharide |
| US11098334B2 (en) | 2017-12-14 | 2021-08-24 | Nutrition & Biosciences USA 4, Inc. | Alpha-1,3-glucan graft copolymers |
| CN112004938A (zh) | 2018-02-23 | 2020-11-27 | 丹尼斯科美国公司 | 用磷酸化酶合成包含α-1,3糖苷键的葡聚糖 |
| WO2019173580A1 (en) * | 2018-03-09 | 2019-09-12 | E. I. Du Pont De Nemours And Company | Engineered glucosyltransferases |
| US11859022B2 (en) | 2018-10-25 | 2024-01-02 | Nutrition & Biosciences USA 4, Inc. | Alpha-1,3-glucan graft copolymers |
| EP3674402A1 (en) * | 2018-12-27 | 2020-07-01 | Sant Dalmai, S.A.U. | Weissella viridescens strain and uses thereof for the synthesis of exopolysaccharides |
| WO2021007264A1 (en) | 2019-07-09 | 2021-01-14 | Nutrition & Biosciences USA 4, Inc. | Engineered alpha-1,3 branching enzymes |
| EP4013241A1 (en) | 2019-08-16 | 2022-06-22 | Nutrition & Biosciences USA 4, Inc. | Flour- and meal-based food products comprising insoluble alpha-1,3-glucan |
| CA3159763A1 (en) | 2019-11-06 | 2021-05-14 | Nutrition & Biosciences USA 4, Inc. | Highly crystalline alpha-1,3-glucan |
| WO2021158543A1 (en) | 2020-02-04 | 2021-08-12 | Nutrition & Biosciences USA 4, Inc. | Aqueous dispersions of insoluble alpha-glucan comprising alpha-1,3 glycosidic linkages |
| PL3907149T3 (pl) | 2020-05-08 | 2022-12-19 | The Procter & Gamble Company | Pojemnik na produkt detergentowy z blokadą |
| CN116134054A (zh) | 2020-06-04 | 2023-05-16 | 营养与生物科学美国4公司 | 右旋糖酐-α-葡聚糖接枝共聚物及其衍生物 |
| ES3033620T3 (en) | 2020-06-10 | 2025-08-06 | Procter & Gamble | A laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
| MX2022014567A (es) * | 2020-06-10 | 2022-12-15 | Procter & Gamble | Composiciones para el cuidado de la ropa o cuidado de la vajilla que comprenden esteres de poli alfa-1,6-glucano. |
| US11965147B2 (en) | 2020-06-10 | 2024-04-23 | The Procter & Gamble Company | Laundry care or dish care composition comprising a poly alpha-1,6-glucan derivative |
| JP2023508432A (ja) * | 2020-06-18 | 2023-03-02 | ザ プロクター アンド ギャンブル カンパニー | ポリビニルアルコールフィルムと、カチオン性ポリα－１，６－グルカンエーテル化合物とを含む水溶性単位用量物品 |
| ES3042438T3 (en) | 2020-07-09 | 2025-11-20 | Procter & Gamble | Lid for a cardboard container wherein the lid comprises a cardboard support element |
| US20240199766A1 (en) | 2021-02-19 | 2024-06-20 | Nutrition & Biosciences USA 4, Inc. | Oxidized polysaccharide derivatives |
| KR20230158572A (ko) * | 2021-03-23 | 2023-11-20 | 다우 글로벌 테크놀로지스 엘엘씨 | 모발 컨디셔닝 제형 |
| CN117242102A (zh) | 2021-05-04 | 2023-12-15 | 营养与生物科学美国4公司 | 包含不溶性α-葡聚糖的组合物 |
| CN117337308A (zh) | 2021-05-04 | 2024-01-02 | 营养与生物科学美国4公司 | 包含氧化的不溶性α-葡聚糖的组合物 |
| WO2022240744A1 (en) * | 2021-05-11 | 2022-11-17 | Elementis Specialties, Inc. | Organoclay compositions having naturally derived ester quaternary ammonium ions or amide quaternary ammonium ions |
| CN113201513B (zh) * | 2021-06-22 | 2023-06-09 | 广西产研院生物制造技术研究所有限公司 | 一种耐热右旋糖酐蔗糖酶突变体及其制备方法与应用 |
| JP2024525685A (ja) | 2021-07-13 | 2024-07-12 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド | カチオン性グルカンエステル誘導体 |
| MX2024004006A (es) | 2021-09-30 | 2024-04-22 | Int N&H Denmark Aps | Metodo para reducir azucar en productos alimenticios. |
| WO2023081341A1 (en) | 2021-11-05 | 2023-05-11 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising one cationic alpha- 1,6-glucan derivative and one alpha- 1,3-glucan |
| CN118382421A (zh) | 2021-12-16 | 2024-07-23 | 营养与生物科学美国4公司 | 包含在水性极性有机溶剂中的阳离子α-葡聚糖醚的组合物 |
| US20250092606A1 (en) | 2022-01-12 | 2025-03-20 | Nutrition & Biosciences USA 4, Inc. | Paper coating compositions comprising rubber and insoluble alpha-glucan |
| KR20240167661A (ko) | 2022-03-21 | 2024-11-27 | 뉴트리션 앤드 바이오사이언시스 유에스에이 4, 인크. | 불용성 알파-글루칸을 포함하는 조성물 |
| JP2025523007A (ja) | 2022-07-11 | 2025-07-17 | ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー，インコーポレイテッド | 両親媒性グルカンエステル誘導体 |
| DE202022104856U1 (de) | 2022-08-29 | 2023-12-01 | Gpi Frankfurt & Augsburg Gmbh | Faltschachtel mit Klick-Laschen |
| US20240108021A1 (en) * | 2022-09-29 | 2024-04-04 | Dupont Nutrition Biosciences Aps | Modification of steviol glycosides by glucosyltransferase enzymes |
| WO2024081773A1 (en) | 2022-10-14 | 2024-04-18 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising water, cationic alpha-1,6-glucan ether and organic solvent |
| AU2023365666A1 (en) | 2022-10-17 | 2025-03-27 | Danisco Us Inc. | Method for improving flavor in plant-based food stuff |
| EP4611720A1 (en) | 2022-11-02 | 2025-09-10 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising xanthan gum and crystalline alpha-1,3-glucan |
| WO2024112740A1 (en) | 2022-11-23 | 2024-05-30 | Nutrition & Biosciences USA 4, Inc. | Hygienic treatment of surfaces with compositions comprising hydrophobically modified alpha-glucan derivative |
| WO2024129951A1 (en) | 2022-12-16 | 2024-06-20 | Nutrition & Biosciences USA 4, Inc. | Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages |
| US20240263162A1 (en) | 2023-02-01 | 2024-08-08 | The Procter & Gamble Company | Detergent compositions containing enzymes |
| EP4658776A1 (en) | 2023-02-01 | 2025-12-10 | Danisco US Inc. | Subtilisin variants and methods of use |
| CN120957606A (zh) * | 2023-03-29 | 2025-11-14 | 国际营养与健康丹麦有限公司 | 经由优选原位产生的α-葡聚糖改变食料质地的方法 |
| EP4704802A1 (en) | 2023-05-03 | 2026-03-11 | Nutrition & Biosciences USA 4, Inc. | Controlling bacterial cell adhesion with alpha-glucan comprising alpha-1,6 glycosidic linkages |
| CN121398902A (zh) | 2023-06-30 | 2026-01-23 | 营养与生物科学美国第四公司 | 多孔α-1,3-葡聚糖组合物 |
| WO2025072417A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide derivatives |
| WO2025072416A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences USA 4, Inc. | Polysaccharide derivatives |
| WO2025072419A1 (en) | 2023-09-29 | 2025-04-03 | Nutrition & Biosciences Usa 1, Llc | Crosslinked alpha-glucan derivatives |
| WO2025117349A1 (en) | 2023-11-28 | 2025-06-05 | Nutrition & Biosciences USA 4, Inc. | Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages |
| WO2025198996A1 (en) | 2024-03-19 | 2025-09-25 | Danisco Us Inc. | Method for improving flavor in foodstuff |
| WO2025199079A1 (en) | 2024-03-20 | 2025-09-25 | Nutrition & Biosciences USA 4, Inc. | Esterification of alpha-glucan comprising alpha-1,6 glycosidic linkages |
| WO2026015598A2 (en) | 2024-07-11 | 2026-01-15 | International N&H Denmark Aps | Method to provide improved texture and stable sucrose levels in foodstuff with glucosyltransferase |
| WO2026024663A1 (en) | 2024-07-24 | 2026-01-29 | Nutrition & Biosciences USA 4, Inc. | Compositions comprising alpha-glucan with alpha-1,3 glycosidic linkages |
| WO2026024921A1 (en) | 2024-07-25 | 2026-01-29 | The Procter & Gamble Company | Detergent composition comprising a subtilisin variant and methods of use |
| WO2026039397A1 (en) | 2024-08-13 | 2026-02-19 | Nutrition & Biosciences USA 4, Inc. | Alpha-glucan graft copolymer derivatives |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4933191A (en) * | 1987-07-01 | 1990-06-12 | Microlife Technics, Inc. | Novel dextran produced by leuconostoc dextranicum |
| JPH07274991A (ja) * | 1994-04-04 | 1995-10-24 | Fujisawa Pharmaceut Co Ltd | デキストランの製造法 |
| EP0881283A1 (fr) * | 1997-05-31 | 1998-12-02 | Societe Des Produits Nestle S.A. | Production de dextrane |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| CN1353193A (zh) * | 2000-11-02 | 2002-06-12 | 杨敏 | 酶法生产右旋糖酐 |
| DE60236287D1 (de) * | 2001-07-20 | 2010-06-17 | Tno | Verwendung eines glukan aus milchsäurebakterien als korrosionsschutzmittel |
| US20060100171A1 (en) | 2002-09-09 | 2006-05-11 | Ekhart Peter F | Branched alpha-glucans for weight management |
| JP4547335B2 (ja) | 2003-12-03 | 2010-09-22 | 明治製菓株式会社 | エンドグルカナーゼｓｔｃｅおよびそれを含むセルラーゼ調製物 |
| JP4644603B2 (ja) | 2003-12-08 | 2011-03-02 | 明治製菓株式会社 | 界面活性剤に耐性なセルラーゼ及びその変換方法 |
| US7399396B2 (en) | 2004-01-16 | 2008-07-15 | Northwestern University | Sparsely cross-linked nanogels: a novel polymer structure for microchannel DNA sequencing |
| CN102086538B (zh) | 2006-10-18 | 2013-03-27 | 东丽株式会社 | 碳纤维 |
| US20090046274A1 (en) | 2007-08-16 | 2009-02-19 | Mchugh Mark A | Light Scattering Methods and Systems Using Supercritical Fluid Solvents to Measure Polymer Molecular Weight and Molecular Weight Distribution |
| CA2816637A1 (en) * | 2010-11-03 | 2012-05-10 | Nestec S.A. | Intrinsic sugar reduction of juices and ready to drink products |
| JP5688798B2 (ja) * | 2010-12-28 | 2015-03-25 | 公立大学法人大阪府立大学 | α−１，３−分枝シクロデキストランの使用方法 |
| FR2978773B1 (fr) | 2011-08-01 | 2015-01-16 | Snf Sas | Nouveau procede de fabrication de dextran, solution de dextran obtenue et utilisations |
| CN103013891B (zh) * | 2012-12-27 | 2014-07-09 | 光明乳业股份有限公司 | 一株肠膜明串珠菌及其胞外多糖与应用 |
| CN103992978B (zh) * | 2014-06-11 | 2016-04-13 | 南京工业大学 | 一株假肠膜明串珠菌及其联产右旋糖酐和甘露醇的方法 |
| AU2015342990B2 (en) * | 2014-11-05 | 2019-08-29 | Nutrition & Biosciences USA 4, Inc. | Enzymatically polymerized gelling dextrans |
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| US11390692B2 (en) | 2022-07-19 |
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| AU2015342990A1 (en) | 2017-04-27 |
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