AU2015204540B2 - Fusion proteins containing insulin-like growth factor-1 and epidermal growth factor and variants thereof and uses thereof - Google Patents
Fusion proteins containing insulin-like growth factor-1 and epidermal growth factor and variants thereof and uses thereof Download PDFInfo
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- AU2015204540B2 AU2015204540B2 AU2015204540A AU2015204540A AU2015204540B2 AU 2015204540 B2 AU2015204540 B2 AU 2015204540B2 AU 2015204540 A AU2015204540 A AU 2015204540A AU 2015204540 A AU2015204540 A AU 2015204540A AU 2015204540 B2 AU2015204540 B2 AU 2015204540B2
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
Landscapes
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
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| CA2800173C (en) | 2010-05-21 | 2019-05-14 | Ulrik Nielsen | Bi-specific fusion proteins |
| US10040840B2 (en) | 2015-10-02 | 2018-08-07 | Silver Creek Pharmaceuticals, Inc. | Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue |
| KR101678392B1 (ko) * | 2016-09-30 | 2016-11-22 | (주)넥스젠바이오텍 | 항산화 기능 및 피부 세포 증식 효과가 증가된 부동화 단백질 및 인간 상피세포성장인자를 포함하는 융합단백질 및 이를 유효성분으로 함유하는 피부 주름 개선용 화장료 조성물 |
| EP3630195A4 (en) * | 2017-05-21 | 2021-03-24 | IGF Oncology, LLC | INSULIN-LIKE GROWTH FACTOR CONJUGATE - CHEMOTHERAPEUTIC PRODUCT FOR THE TREATMENT OF MYELODYSPLASIC SYNDROME |
| US12222354B2 (en) * | 2021-03-19 | 2025-02-11 | Quest Diagnostics Investments Llc | Identification and quantitation of insulin-like growth factor-I variants by mass spectrometry |
| AU2023417644A1 (en) * | 2022-12-30 | 2025-07-31 | Lg Chem, Ltd. | Recombinant fusion protein having modified cysteine residue for antigen delivery and uses thereof |
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| WO2009030720A2 (en) * | 2007-09-06 | 2009-03-12 | Novozymes Biopharma Dk A/S | Process for producing a recombinant protein |
| US20100121036A1 (en) * | 2006-08-31 | 2010-05-13 | F. Hoffmann-La Roche Ag | Method for the production of insulin-like growth factor-1 |
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| US4975278A (en) | 1988-02-26 | 1990-12-04 | Bristol-Myers Company | Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells |
| US4876242A (en) | 1987-09-21 | 1989-10-24 | Merck & Co., Inc. | Human insulin-like growth factor analoges with reduced binding to serum carrier proteins and their production in yeast |
| FI890312A7 (fi) * | 1988-01-25 | 1989-07-26 | Oncogen | Amfireguliini: uusi bifunktionaalinen kasvua moduloiva glykoproteiini |
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2019
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|---|---|---|---|---|
| US20100121036A1 (en) * | 2006-08-31 | 2010-05-13 | F. Hoffmann-La Roche Ag | Method for the production of insulin-like growth factor-1 |
| WO2009030720A2 (en) * | 2007-09-06 | 2009-03-12 | Novozymes Biopharma Dk A/S | Process for producing a recombinant protein |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015204540A1 (en) | 2016-08-04 |
| WO2015106224A2 (en) | 2015-07-16 |
| US10967049B2 (en) | 2021-04-06 |
| US20180021408A1 (en) | 2018-01-25 |
| US9675671B2 (en) | 2017-06-13 |
| US20170266260A1 (en) | 2017-09-21 |
| US20150196656A1 (en) | 2015-07-16 |
| JP2017503862A (ja) | 2017-02-02 |
| CA2936675C (en) | 2023-06-27 |
| JP6835590B2 (ja) | 2021-02-24 |
| CA2936675A1 (en) | 2015-07-16 |
| EP3094339B1 (en) | 2019-12-11 |
| US20190336580A1 (en) | 2019-11-07 |
| EP3094339A2 (en) | 2016-11-23 |
| EP3094339A4 (en) | 2017-06-07 |
| US9801923B2 (en) | 2017-10-31 |
| WO2015106224A3 (en) | 2015-11-12 |
| US10391147B2 (en) | 2019-08-27 |
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