AU2015204218B2 - Pharmaceutical compositions comprising AZD9291 - Google Patents

Pharmaceutical compositions comprising AZD9291 Download PDF

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Publication number
AU2015204218B2
AU2015204218B2 AU2015204218A AU2015204218A AU2015204218B2 AU 2015204218 B2 AU2015204218 B2 AU 2015204218B2 AU 2015204218 A AU2015204218 A AU 2015204218A AU 2015204218 A AU2015204218 A AU 2015204218A AU 2015204218 B2 AU2015204218 B2 AU 2015204218B2
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AU
Australia
Prior art keywords
pharmaceutical
parts
pharmaceutical composition
agent
diluents
Prior art date
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AU2015204218A
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English (en)
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AU2015204218A1 (en
Inventor
Cindy FINNIE
Steven Anthony Raw
David Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50191689&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2015204218(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2015204218A1 publication Critical patent/AU2015204218A1/en
Application granted granted Critical
Publication of AU2015204218B2 publication Critical patent/AU2015204218B2/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2015204218A 2014-01-02 2015-01-02 Pharmaceutical compositions comprising AZD9291 Active AU2015204218B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1400034.3 2014-01-02
GBGB1400034.3A GB201400034D0 (en) 2014-01-02 2014-01-02 Pharmaceutical Compositions comprising AZD9291
PCT/GB2015/050001 WO2015101791A1 (en) 2014-01-02 2015-01-02 Pharmaceutical compositions comprising azd9291

Publications (2)

Publication Number Publication Date
AU2015204218A1 AU2015204218A1 (en) 2016-07-07
AU2015204218B2 true AU2015204218B2 (en) 2017-06-15

Family

ID=50191689

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015204218A Active AU2015204218B2 (en) 2014-01-02 2015-01-02 Pharmaceutical compositions comprising AZD9291

Country Status (37)

Country Link
US (6) US10183020B2 (enExample)
EP (1) EP3089741B1 (enExample)
JP (1) JP6588915B2 (enExample)
KR (1) KR102336378B1 (enExample)
CN (2) CN105848647B (enExample)
AR (1) AR098989A1 (enExample)
AU (1) AU2015204218B2 (enExample)
CA (1) CA2933403C (enExample)
CL (1) CL2016001609A1 (enExample)
CR (1) CR20160310A (enExample)
CY (1) CY1124848T1 (enExample)
DK (1) DK3089741T3 (enExample)
DO (1) DOP2016000156A (enExample)
EA (1) EA034243B9 (enExample)
ES (1) ES2873226T3 (enExample)
GB (1) GB201400034D0 (enExample)
GT (1) GT201600142A (enExample)
HR (1) HRP20210749T1 (enExample)
HU (1) HUE054344T2 (enExample)
IL (1) IL246186B (enExample)
LT (1) LT3089741T (enExample)
MX (1) MX367358B (enExample)
MY (1) MY183536A (enExample)
NI (1) NI201600098A (enExample)
NZ (1) NZ721298A (enExample)
PE (1) PE20161170A1 (enExample)
PH (1) PH12016501310B1 (enExample)
PL (1) PL3089741T3 (enExample)
PT (1) PT3089741T (enExample)
RS (1) RS61927B1 (enExample)
SG (1) SG11201605339QA (enExample)
SI (1) SI3089741T1 (enExample)
SM (1) SMT202100330T1 (enExample)
TW (1) TWI702953B (enExample)
UY (1) UY35933A (enExample)
WO (1) WO2015101791A1 (enExample)
ZA (1) ZA201605300B (enExample)

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GB201400034D0 (en) * 2014-01-02 2014-02-19 Astrazeneca Ab Pharmaceutical Compositions comprising AZD9291
NO2699580T3 (enExample) 2014-01-24 2018-02-24
SG11201809751XA (en) 2016-05-26 2018-12-28 Zeno Royalties & Milestones Llc Egfr inhibitor compounds
CN108057036B (zh) * 2016-11-07 2023-06-13 正大天晴药业集团股份有限公司 一种egfr抑制剂的固体药物组合物
CN107176954B (zh) * 2017-06-02 2019-01-11 无锡双良生物科技有限公司 一种egfr抑制剂的药用盐及其晶型、制备方法和应用
CN110013468B (zh) * 2018-01-09 2022-02-18 北京福元医药股份有限公司 一种azd9291氘代衍生物药物制剂
WO2019138346A1 (en) * 2018-01-10 2019-07-18 Alembic Pharmaceuticals Limited Pharmaceutical composition of osimertinib
TW201941773A (zh) * 2018-02-12 2019-11-01 瑞典商阿斯特捷利康公司 用於治療非小細胞肺癌之奧希替尼
PL3758708T3 (pl) * 2018-03-01 2025-03-31 Astrazeneca Ab Kompozycje farmaceutyczne zawierające (2s)-{(1s)-1-cyjano-2-[4-(3-metylo-2-okso-2,3-dihydro-1,3-benzoksazol-5-ilo)fenylo]etylo}-1,4-oksazepano-2-karboksyamid
WO2019178868A1 (zh) 2018-03-23 2019-09-26 无锡双良生物科技有限公司 一种药物组合物及其制备方法和用途
EP3823627A4 (en) 2018-07-17 2022-04-20 Insmed Incorporated CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES FOR THE TREATMENT OF LUPUS ENEHROPATHY
KR20200043618A (ko) 2018-10-18 2020-04-28 주식회사유한양행 아미노피리미딘 유도체 또는 이의 염을 포함하는 경구투여용 약학 조성물
MX2021011810A (es) 2019-03-29 2021-10-26 Astrazeneca Ab Osimertinib para su uso en el tratamiento de cancer de pulmon de celulas no peque?as.
US20210161897A1 (en) 2019-11-12 2021-06-03 Astrazeneca Ab Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
AU2021211871A1 (en) 2020-01-20 2022-09-08 Astrazeneca Ab Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
US20210369709A1 (en) 2020-05-27 2021-12-02 Astrazeneca Ab EGFR TKIs FOR USE IN THE TREATMENT OF NON-SMALL CELL LUNG CANCER
TW202304457A (zh) * 2021-03-22 2023-02-01 瑞典商阿斯特捷利康公司 配製物
IL315848A (en) 2022-03-31 2024-11-01 Astrazeneca Ab Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in combination with an AKT inhibitor for cancer treatment
CA3249080A1 (en) 2022-04-28 2023-11-02 Astrazeneca Ab Condensed bicyclic heteroaromatic compounds and their use in the treatment of cancer
US20240116926A1 (en) 2022-04-28 2024-04-11 Astrazeneca Ab Heteroaromatic compounds
WO2023209090A1 (en) 2022-04-28 2023-11-02 Astrazeneca Ab Bicyclic heteroaromatic compounds and their application in the treatment of cancer
WO2023209088A1 (en) 2022-04-28 2023-11-02 Astrazeneca Ab Bicyclic heteroaromatic compounds and their use in the treatment of cancer
KR20250029133A (ko) 2022-06-27 2025-03-04 아스트라제네카 아베 암 치료를 위한 표피성장인자 수용체 티로신 키나제 억제제를 포함하는 조합물
CN119654152A (zh) 2022-07-08 2025-03-18 阿斯利康(瑞典)有限公司 与hgf-受体抑制剂组合用于治疗癌症的表皮生长因子受体酪氨酸激酶抑制剂
EP4646265A1 (en) 2023-01-06 2025-11-12 Insmed Incorporated Novel, reversible dpp1 inhibitors and uses thereof
WO2025092926A1 (zh) * 2023-10-31 2025-05-08 浙江同源康医药股份有限公司 一种嘧啶类衍生物的药物组合物

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WO2013014448A1 (en) * 2011-07-27 2013-01-31 Astrazeneca Ab 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer

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US6881737B2 (en) 2001-04-11 2005-04-19 Amgen Inc. Substituted triazinyl acrylamide derivatives and methods of use
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Patent Citations (1)

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Also Published As

Publication number Publication date
HRP20210749T1 (hr) 2021-06-25
CN114712362A (zh) 2022-07-08
CA2933403C (en) 2022-03-29
SG11201605339QA (en) 2016-07-28
US20220395502A1 (en) 2022-12-15
SI3089741T1 (sl) 2021-08-31
AR098989A1 (es) 2016-06-22
HUE054344T2 (hu) 2021-08-30
US20190111057A1 (en) 2019-04-18
IL246186A0 (en) 2016-07-31
TWI702953B (zh) 2020-09-01
AU2015204218A1 (en) 2016-07-07
MX367358B (es) 2019-08-16
CN105848647A (zh) 2016-08-10
RS61927B1 (sr) 2021-06-30
CN105848647B (zh) 2022-04-26
EA034243B9 (ru) 2020-04-10
JP6588915B2 (ja) 2019-10-09
HK1225655A1 (zh) 2017-09-15
DK3089741T3 (da) 2021-06-07
JP2017501201A (ja) 2017-01-12
US20200360378A1 (en) 2020-11-19
PH12016501310B1 (en) 2022-07-06
ES2873226T3 (es) 2021-11-03
PH12016501310A1 (en) 2016-09-14
TW201609101A (zh) 2016-03-16
MX2016008744A (es) 2016-09-08
GT201600142A (es) 2019-08-12
WO2015101791A1 (en) 2015-07-09
KR20160101720A (ko) 2016-08-25
US20250017930A1 (en) 2025-01-16
NZ721298A (en) 2017-10-27
GB201400034D0 (en) 2014-02-19
EP3089741A1 (en) 2016-11-09
IL246186B (en) 2020-07-30
EA201691242A1 (ru) 2016-12-30
CY1124848T1 (el) 2022-11-25
UY35933A (es) 2015-07-31
CR20160310A (es) 2016-09-23
CL2016001609A1 (es) 2016-12-09
PT3089741T (pt) 2021-06-11
US20160324854A1 (en) 2016-11-10
MY183536A (en) 2021-02-25
EP3089741B1 (en) 2021-03-10
SMT202100330T1 (it) 2021-07-12
PL3089741T3 (pl) 2021-09-27
CA2933403A1 (en) 2015-07-09
KR102336378B1 (ko) 2021-12-08
DOP2016000156A (es) 2016-08-15
US20240189310A1 (en) 2024-06-13
LT3089741T (lt) 2021-06-10
PE20161170A1 (es) 2016-11-24
EA034243B1 (ru) 2020-01-21
NI201600098A (es) 2016-12-20
ZA201605300B (en) 2022-10-26
US10183020B2 (en) 2019-01-22

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