AU2014338520B2 - A viral vaccine and methods of manufacture thereof - Google Patents

A viral vaccine and methods of manufacture thereof Download PDF

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Publication number
AU2014338520B2
AU2014338520B2 AU2014338520A AU2014338520A AU2014338520B2 AU 2014338520 B2 AU2014338520 B2 AU 2014338520B2 AU 2014338520 A AU2014338520 A AU 2014338520A AU 2014338520 A AU2014338520 A AU 2014338520A AU 2014338520 B2 AU2014338520 B2 AU 2014338520B2
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AU
Australia
Prior art keywords
bulk
virus
purified
japanese encephalitis
inactivated
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AU2014338520A
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English (en)
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AU2014338520A1 (en
Inventor
Prasanna Kumar DUVVURU
Venkatesan RAMASAMY
Krishna Mohan Vadrevu
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Bharat Biotech International Ltd
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Bharat Biotech International Ltd
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Publication of AU2014338520A1 publication Critical patent/AU2014338520A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24151—Methods of production or purification of viral material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2014338520A 2013-09-14 2014-09-08 A viral vaccine and methods of manufacture thereof Active AU2014338520B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN4135/CHE/2013 2013-09-14
PCT/IN2014/000585 WO2015059714A1 (en) 2013-09-14 2014-09-08 Emergency mode in a hybrid vehicle
IN4135CH2013 IN2013CH04135A (enrdf_load_stackoverflow) 2013-09-14 2014-09-08

Publications (2)

Publication Number Publication Date
AU2014338520A1 AU2014338520A1 (en) 2016-03-31
AU2014338520B2 true AU2014338520B2 (en) 2019-12-05

Family

ID=52997726

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014338520A Active AU2014338520B2 (en) 2013-09-14 2014-09-08 A viral vaccine and methods of manufacture thereof

Country Status (6)

Country Link
CN (1) CN105744952A (enrdf_load_stackoverflow)
AU (1) AU2014338520B2 (enrdf_load_stackoverflow)
IN (1) IN2013CH04135A (enrdf_load_stackoverflow)
PH (1) PH12016500500A1 (enrdf_load_stackoverflow)
RU (1) RU2706693C2 (enrdf_load_stackoverflow)
WO (1) WO2015059714A1 (enrdf_load_stackoverflow)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN108601825B (zh) * 2015-07-16 2023-06-20 巴拉特生物技术国际有限公司 疫苗组合物
WO2017083286A1 (en) 2015-11-09 2017-05-18 University Of Notre Dame Particle size purification method and devices
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
CN111511395B (zh) 2017-11-03 2024-10-15 武田疫苗股份有限公司 用于将寨卡病毒灭活和用于确定灭活完全性的方法
WO2019108976A1 (en) 2017-11-30 2019-06-06 Takeda Vaccines, Inc. Method for inactivating zika virus and related methods
EP3581646A1 (en) * 2018-06-15 2019-12-18 Themis Bioscience GmbH Integrated manufacturing and chromatographic system for virus production
WO2020036869A1 (en) 2018-08-16 2020-02-20 Emd Millipore Corporation Closed bioprocessing device
CN111394321A (zh) * 2020-03-30 2020-07-10 无锡加莱克色谱科技有限公司 病毒颗粒纯化用超大孔径层析介质及其应用方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011762A1 (en) * 1997-08-28 1999-03-11 Cheil Jedang Corporation An attenuated japanese encephalitis virus adapted to vero cell and a japanese encephalitis vaccine
WO2010137036A2 (en) * 2009-05-25 2010-12-02 Panacea Biotec Ltd Novel japanese encephalitis vaccine and method of manufacturing the same
CN102100910A (zh) * 2009-12-21 2011-06-22 北京清大天一科技有限公司 一种生产病毒疫苗的方法
WO2012073257A2 (en) * 2010-11-30 2012-06-07 Bharat Biotech International Limited Vaccine formulation for prophylaxis and treatment of chandipura virus infections in mammals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9580692B2 (en) * 2012-02-29 2017-02-28 Ge Healthcare Bioprocess R&D Ab Method for endotoxin removal

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011762A1 (en) * 1997-08-28 1999-03-11 Cheil Jedang Corporation An attenuated japanese encephalitis virus adapted to vero cell and a japanese encephalitis vaccine
WO2010137036A2 (en) * 2009-05-25 2010-12-02 Panacea Biotec Ltd Novel japanese encephalitis vaccine and method of manufacturing the same
CN102100910A (zh) * 2009-12-21 2011-06-22 北京清大天一科技有限公司 一种生产病毒疫苗的方法
WO2012073257A2 (en) * 2010-11-30 2012-06-07 Bharat Biotech International Limited Vaccine formulation for prophylaxis and treatment of chandipura virus infections in mammals

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Åkerblom, A. & Bergvall, P. "Constraints on Vaccine Production: The Need for Improved Productivity and Economy." Advertisement in: BioProcess International, Industry Yearbook 2012-2013, page 64&66. *
Beasley, D.W. et al., "Current use and development of vaccines for Japanese encephalitis" Expert Opin Biol Ther. 2008 Jan;8(1):95-106. *
Sinha, K. "India develops indigenous Japanese Encephalitis vaccine" The Times of India (17 December 2012) *
Toriniwa, H. et al., "Long-term stability of Vero cell-derived inactivated Japanese encephalitis vaccine prepared using serum-free medium", Vaccine. 2008 Jul 4;26(29-30):3680-9. Epub 2008 May 19. *

Also Published As

Publication number Publication date
RU2016114285A (ru) 2017-10-19
WO2015059714A8 (en) 2015-06-18
CN105744952A (zh) 2016-07-06
IN2013CH04135A (enrdf_load_stackoverflow) 2015-08-14
RU2016114285A3 (enrdf_load_stackoverflow) 2018-07-16
RU2706693C2 (ru) 2019-11-20
PH12016500500A1 (en) 2016-06-13
WO2015059714A1 (en) 2015-04-30
AU2014338520A1 (en) 2016-03-31

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