AU2014301493B2 - A process for preparing a cross-linked hyaluronic acid product - Google Patents
A process for preparing a cross-linked hyaluronic acid product Download PDFInfo
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- AU2014301493B2 AU2014301493B2 AU2014301493A AU2014301493A AU2014301493B2 AU 2014301493 B2 AU2014301493 B2 AU 2014301493B2 AU 2014301493 A AU2014301493 A AU 2014301493A AU 2014301493 A AU2014301493 A AU 2014301493A AU 2014301493 B2 AU2014301493 B2 AU 2014301493B2
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- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000013587 production medium Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
- C08J3/244—Stepwise homogeneous crosslinking of one polymer with one crosslinking system, e.g. partial curing
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
- C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP2013063718 | 2013-06-28 | ||
EPPCT/EP2013/063718 | 2013-06-28 | ||
PCT/EP2014/061674 WO2014206701A1 (fr) | 2013-06-28 | 2014-06-05 | Procédé pour préparer un produit réticulé d'acide hyaluronique |
Publications (2)
Publication Number | Publication Date |
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AU2014301493A1 AU2014301493A1 (en) | 2016-02-11 |
AU2014301493B2 true AU2014301493B2 (en) | 2018-11-29 |
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AU2014301493A Ceased AU2014301493B2 (en) | 2013-06-28 | 2014-06-05 | A process for preparing a cross-linked hyaluronic acid product |
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US (2) | US10077320B2 (fr) |
JP (1) | JP6479783B2 (fr) |
KR (1) | KR20160025026A (fr) |
CN (2) | CN105473623B (fr) |
AU (1) | AU2014301493B2 (fr) |
BR (1) | BR112015031457A2 (fr) |
CA (1) | CA2916330A1 (fr) |
HK (1) | HK1224315A1 (fr) |
MX (1) | MX368941B (fr) |
RU (1) | RU2689559C2 (fr) |
WO (1) | WO2014206701A1 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3032617B1 (fr) * | 2015-02-16 | 2018-03-16 | Kylane Laboratoires Sa | Procede de preparation d un hydrogel injectable; hydrogel obtenu; utilisation de l hydrogel obtenu |
WO2017016917A1 (fr) | 2015-07-27 | 2017-02-02 | Galderma Sa | Procédé de réticulation efficace d'acide hyaluronique |
EP3162813A1 (fr) * | 2015-11-02 | 2017-05-03 | Merz Pharma GmbH & Co. KGaA | Procédé pour appauvrir des espèces d'époxyde dans des compositions de gel poly-saccharide réticulées et compositions ainsi obtenues |
KR20170090965A (ko) * | 2016-01-29 | 2017-08-08 | 한미약품 주식회사 | 복합 히알루론산 가교물 및 그 제조방법 |
WO2017131298A1 (fr) * | 2016-01-29 | 2017-08-03 | Hanmi Pharm. Co., Ltd. | Combinaison d'acides hyaluroniques réticulés et son procédé de préparation |
UA127350C2 (uk) | 2017-06-26 | 2023-07-26 | Іволвд Бай Нейчер, Інк. | Тканинний філер на основі шовку і гіалуронової кислоти |
CN108395552B (zh) * | 2017-12-15 | 2021-03-19 | 浙江景嘉医疗科技有限公司 | 一种单相交联透明质酸钠凝胶的制备方法 |
WO2020116999A1 (fr) * | 2018-12-07 | 2020-06-11 | 한미약품 주식회사 | Acide hyaluronique réticulé, hydrogel d'acide hyaluronique et procédé de production d'acide hyaluronique réticulé et d'hydrogel d'acide hyaluronique |
CN113166434A (zh) * | 2018-12-07 | 2021-07-23 | 韩美药品株式会社 | 交联透明质酸、透明质酸水凝胶及其制备方法 |
US20220160936A1 (en) * | 2019-04-02 | 2022-05-26 | Volumina Medical Sa | Composition comprising a cross-linked polyol |
USD918654S1 (en) | 2019-06-06 | 2021-05-11 | Sharkninja Operating Llc | Grill plate |
CN112147029A (zh) * | 2019-06-28 | 2020-12-29 | 杭州协合医疗用品有限公司 | 一种交联透明质酸钠凝胶溶胀度的测定方法 |
EP3995530A4 (fr) * | 2019-09-27 | 2022-08-31 | LG Chem, Ltd. | Procédé de préparation de microparticules polymères, microparticules polymères, composition médicale les comprenant, composition cosmétique, article médical et article cosmétique |
KR102425496B1 (ko) * | 2020-05-08 | 2022-07-26 | 주식회사 종근당 | 고탄성, 고점도 및 고유효 가교율을 갖는 히알루론산 가교체, 및 이의 제조방법 |
KR102527095B1 (ko) | 2020-12-18 | 2023-04-28 | 충남대학교산학협력단 | 가교 처리된 히알루론산 조성물의 가교율 측정방법 |
CN116997371A (zh) * | 2021-03-02 | 2023-11-03 | 赛姆提斯 | 基于聚合物的可植入或可注射产品及其制备方法 |
CN113278170B (zh) * | 2021-06-15 | 2021-11-16 | 苏州大学 | 一种化学交联透明质酸水凝胶及其制备方法与应用 |
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WO1987007898A1 (fr) * | 1986-06-18 | 1987-12-30 | Pharmacia Ab | Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides |
WO2000046253A1 (fr) * | 1999-02-03 | 2000-08-10 | Vitrolife Uk Limited | Procede relatif a l'elaboration de derives d'acide hyaluronique a reticulations multiples |
EP1837347A1 (fr) * | 2006-03-22 | 2007-09-26 | BioPolymer GmbH & Co. KG | Gels doublement réticulés d'acide hyaluronique et leur utilisation |
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US4716224A (en) * | 1984-05-04 | 1987-12-29 | Seikagaku Kogyo Co. Ltd. | Crosslinked hyaluronic acid and its use |
SE8900422D0 (sv) * | 1989-02-08 | 1989-02-08 | Pharmacia Ab | Tvaerbundna hyaluronatgeler samt foerfarande foer framstaellning av dessa |
US5827937A (en) * | 1995-07-17 | 1998-10-27 | Q Med Ab | Polysaccharide gel composition |
IT1303735B1 (it) | 1998-11-11 | 2001-02-23 | Falorni Italia Farmaceutici S | Acidi ialuronici reticolati e loro usi medici. |
FR2811996B1 (fr) * | 2000-07-19 | 2003-08-08 | Corneal Ind | Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations |
AU2003901834A0 (en) * | 2003-04-17 | 2003-05-01 | Clearcoll Pty Ltd | Cross-linked polysaccharide compositions |
FR2865737B1 (fr) * | 2004-02-03 | 2006-03-31 | Anteis Sa | Gel reticule biocompatible |
JP2006111867A (ja) | 2004-09-15 | 2006-04-27 | Seikagaku Kogyo Co Ltd | 光反応性多糖、その光架橋多糖生成物及び医用材料 |
KR101288748B1 (ko) * | 2004-09-15 | 2013-07-23 | 세이가가쿠 고교 가부시키가이샤 | 광반응성 다당, 광가교 다당 생성물, 이들의 제조 방법 및이로부터 제조된 의료용 재료 |
US20060105022A1 (en) | 2004-11-15 | 2006-05-18 | Shiseido Co., Ltd. | Process for preparing crosslinked hyaluronic acid gel |
EP1818344A4 (fr) | 2004-11-15 | 2012-04-18 | Shiseido Co Ltd | Methode de synthese d'un gel reticule d'acide hyaluronique |
PT1817347T (pt) * | 2004-11-24 | 2017-07-21 | Albumedix As | Resumo |
CN101153061A (zh) * | 2006-09-29 | 2008-04-02 | 北京普麦迪克生物技术研究所 | 一种透明质酸及其二次交联形成凝胶的方法 |
IT1395392B1 (it) * | 2009-08-27 | 2012-09-14 | Fidia Farmaceutici | Geli viscoelastici come nuovi filler |
EP2979709B1 (fr) * | 2010-10-20 | 2017-08-02 | Allergan Holdings France S.A.S. | Fils d'acide hyaluronique réticulé et utilisation de ceux-ci |
-
2014
- 2014-06-05 MX MX2015017525A patent/MX368941B/es active IP Right Grant
- 2014-06-05 CN CN201480046128.XA patent/CN105473623B/zh active Active
- 2014-06-05 CA CA2916330A patent/CA2916330A1/fr not_active Abandoned
- 2014-06-05 US US14/901,462 patent/US10077320B2/en active Active
- 2014-06-05 WO PCT/EP2014/061674 patent/WO2014206701A1/fr active Application Filing
- 2014-06-05 CN CN201910351054.5A patent/CN110003360A/zh active Pending
- 2014-06-05 JP JP2016522367A patent/JP6479783B2/ja not_active Expired - Fee Related
- 2014-06-05 KR KR1020167002517A patent/KR20160025026A/ko not_active Application Discontinuation
- 2014-06-05 RU RU2016101736A patent/RU2689559C2/ru not_active IP Right Cessation
- 2014-06-05 AU AU2014301493A patent/AU2014301493B2/en not_active Ceased
- 2014-06-05 BR BR112015031457A patent/BR112015031457A2/pt not_active Application Discontinuation
-
2016
- 2016-11-03 HK HK16112652.6A patent/HK1224315A1/zh unknown
-
2018
- 2018-08-24 US US16/111,493 patent/US20190062461A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1987007898A1 (fr) * | 1986-06-18 | 1987-12-30 | Pharmacia Ab | Materiau forme de polysaccharides contenant des groupes carboxyles, et procede de production de ces polysaccharides |
WO2000046253A1 (fr) * | 1999-02-03 | 2000-08-10 | Vitrolife Uk Limited | Procede relatif a l'elaboration de derives d'acide hyaluronique a reticulations multiples |
EP1837347A1 (fr) * | 2006-03-22 | 2007-09-26 | BioPolymer GmbH & Co. KG | Gels doublement réticulés d'acide hyaluronique et leur utilisation |
Also Published As
Publication number | Publication date |
---|---|
JP6479783B2 (ja) | 2019-03-06 |
BR112015031457A2 (pt) | 2017-07-25 |
JP2016523303A (ja) | 2016-08-08 |
CN105473623B (zh) | 2019-10-29 |
HK1224315A1 (zh) | 2017-08-18 |
RU2016101736A3 (fr) | 2018-03-20 |
US20190062461A1 (en) | 2019-02-28 |
KR20160025026A (ko) | 2016-03-07 |
WO2014206701A1 (fr) | 2014-12-31 |
RU2689559C2 (ru) | 2019-05-28 |
AU2014301493A1 (en) | 2016-02-11 |
US20160376382A1 (en) | 2016-12-29 |
US10077320B2 (en) | 2018-09-18 |
CA2916330A1 (fr) | 2014-12-31 |
CN105473623A (zh) | 2016-04-06 |
CN110003360A (zh) | 2019-07-12 |
RU2016101736A (ru) | 2017-08-02 |
MX2015017525A (es) | 2016-06-30 |
MX368941B (es) | 2019-10-22 |
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