AU2014273091B2 - A LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof - Google Patents

A LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof Download PDF

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AU2014273091B2
AU2014273091B2 AU2014273091A AU2014273091A AU2014273091B2 AU 2014273091 B2 AU2014273091 B2 AU 2014273091B2 AU 2014273091 A AU2014273091 A AU 2014273091A AU 2014273091 A AU2014273091 A AU 2014273091A AU 2014273091 B2 AU2014273091 B2 AU 2014273091B2
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dna
sequence
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Alexander ASTRAKHAN
Jordan JARJOUR
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Cellectis SA
Precision Genome Engineering Inc
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Precision Genome Engineering Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2014273091A 2013-05-31 2014-05-28 A LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof Active AU2014273091B2 (en)

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DKPA201370303 2013-05-31
DKPA201370303 2013-05-31
PCT/EP2014/061189 WO2014191527A1 (en) 2013-05-31 2014-05-28 A laglidadg homing endonuclease cleaving the t cell receptor alpha gene and uses thereof

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AU2014273091A1 AU2014273091A1 (en) 2015-12-03
AU2014273091B2 true AU2014273091B2 (en) 2019-12-12

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JP (1) JP6450371B2 (enExample)
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CA (1) CA2913872C (enExample)
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CA2913872A1 (en) 2014-12-04
DK3004338T3 (en) 2019-04-08
US20160130569A1 (en) 2016-05-12
WO2014191527A1 (en) 2014-12-04
JP6450371B2 (ja) 2019-01-09
CA2913872C (en) 2022-01-18
EP3004338B1 (en) 2019-01-02
US10000746B2 (en) 2018-06-19
ES2716867T3 (es) 2019-06-17
HK1223394A1 (en) 2017-07-28
JP2016520320A (ja) 2016-07-14
EP3004338A1 (en) 2016-04-13
AU2014273091A1 (en) 2015-12-03

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