AU2014252769B2 - Biodegradable network polymers for regenerative medicine and tissue engineering - Google Patents

Biodegradable network polymers for regenerative medicine and tissue engineering Download PDF

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Publication number
AU2014252769B2
AU2014252769B2 AU2014252769A AU2014252769A AU2014252769B2 AU 2014252769 B2 AU2014252769 B2 AU 2014252769B2 AU 2014252769 A AU2014252769 A AU 2014252769A AU 2014252769 A AU2014252769 A AU 2014252769A AU 2014252769 B2 AU2014252769 B2 AU 2014252769B2
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Prior art keywords
monomer
polyether
biodegradable
network polymer
chloride
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AU2014252769A
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AU2014252769A1 (en
Inventor
Anton Blencowe
Berkay OZCELIK
Greg Guanghua Qiao
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University of Melbourne
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University of Melbourne
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Priority claimed from AU2013901223A external-priority patent/AU2013901223A0/en
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C08G65/3324—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof cyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/08—Polyethers derived from hydroxy compounds or from their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/06—Biodegradable
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/16—Applications used for films

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2014252769A 2013-04-10 2014-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering Active AU2014252769B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014252769A AU2014252769B2 (en) 2013-04-10 2014-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2013901223A AU2013901223A0 (en) 2013-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering
AU2013901223 2013-04-10
PCT/AU2014/000391 WO2014165917A1 (en) 2013-04-10 2014-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering
AU2014252769A AU2014252769B2 (en) 2013-04-10 2014-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering

Publications (2)

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AU2014252769A1 AU2014252769A1 (en) 2015-11-26
AU2014252769B2 true AU2014252769B2 (en) 2017-11-30

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AU2014252769A Active AU2014252769B2 (en) 2013-04-10 2014-04-10 Biodegradable network polymers for regenerative medicine and tissue engineering

Country Status (7)

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US (2) US10179834B2 (enExample)
EP (1) EP2983726A4 (enExample)
JP (1) JP6403754B2 (enExample)
CN (1) CN105358185B (enExample)
AU (1) AU2014252769B2 (enExample)
BR (1) BR112015025904A2 (enExample)
WO (1) WO2014165917A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112870433B (zh) * 2021-01-18 2022-04-01 华东理工大学 DFO和rhBMP-2协同激发成骨的复合支架及其制备方法和应用
CN114181360A (zh) * 2021-12-08 2022-03-15 南京工业大学 一种超声波刺激响应聚氨酯及其制备方法
WO2025006821A2 (en) * 2023-06-30 2025-01-02 The University Of Melbourne Polymer compositions and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004211008A (ja) * 2003-01-07 2004-07-29 Mitsubishi Chemicals Corp 生分解性共重合体とその製造方法
US20110124765A1 (en) * 2008-05-07 2011-05-26 Board Of Regents, The University Of Texas System Versatile Biodegradable Elastic Polymers Featured with Dual Crosslinking Mechanism for Biomedical Applications
US20120178824A1 (en) * 2011-01-11 2012-07-12 Henkel Ag & Co. Kgaa Hydrogels based on esters of polyisobutenesuccinic acid

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US4110276A (en) * 1976-11-02 1978-08-29 The Procter & Gamble Company Polyester foam materials
JPS58160316A (ja) 1982-03-17 1983-09-22 Dai Ichi Kogyo Seiyaku Co Ltd 高分子量化合物の製造法
EP0696605B1 (de) * 1994-08-10 2000-09-20 Peter Neuenschwander Biokompatibles Blockcopolymer
GB9700508D0 (en) * 1997-01-11 1997-02-26 Smith & Nephew Hydrogels
AU7571501A (en) 2000-08-04 2002-02-18 Orthogem Ltd Porous synthetic bone graft and method of manufacture thereof
JP2003274800A (ja) * 2002-03-22 2003-09-30 Daisee Kogyo Kk 疑似餌用生分解性素材
DE10240817A1 (de) 2002-08-30 2004-03-11 Basf Ag Verfahren zur Herstellung hyperverzweigter, wasserlöslicher Polyester
MXPA05008653A (es) 2003-02-14 2006-04-27 Depuy Spine Inc Dispositivo de fusion intervertebral formado in situ.
JP2007517543A (ja) 2003-11-20 2007-07-05 アンジオテック インターナショナル アーゲー ポリマー化合物とその使用法
US20090028957A1 (en) * 2005-04-19 2009-01-29 Daniloff George Y Implantable Tissue-Reactive Biomaterial Compositions and Systems, and Methods of Us Thereof
JP2007204614A (ja) * 2006-02-02 2007-08-16 Nisshin Oillio Group Ltd 樹脂用可塑剤及び該樹脂用可塑剤を含有する樹脂組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004211008A (ja) * 2003-01-07 2004-07-29 Mitsubishi Chemicals Corp 生分解性共重合体とその製造方法
US20110124765A1 (en) * 2008-05-07 2011-05-26 Board Of Regents, The University Of Texas System Versatile Biodegradable Elastic Polymers Featured with Dual Crosslinking Mechanism for Biomedical Applications
US20120178824A1 (en) * 2011-01-11 2012-07-12 Henkel Ag & Co. Kgaa Hydrogels based on esters of polyisobutenesuccinic acid

Also Published As

Publication number Publication date
CN105358185B (zh) 2019-08-06
AU2014252769A1 (en) 2015-11-26
EP2983726A4 (en) 2016-12-14
US20160060392A1 (en) 2016-03-03
EP2983726A1 (en) 2016-02-17
CN105358185A (zh) 2016-02-24
WO2014165917A1 (en) 2014-10-16
US20190194389A1 (en) 2019-06-27
JP6403754B2 (ja) 2018-10-10
JP2016518485A (ja) 2016-06-23
BR112015025904A2 (pt) 2017-07-25
US10179834B2 (en) 2019-01-15

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