AU2014243988B2 - Oxygen sensors - Google Patents

Oxygen sensors Download PDF

Info

Publication number
AU2014243988B2
AU2014243988B2 AU2014243988A AU2014243988A AU2014243988B2 AU 2014243988 B2 AU2014243988 B2 AU 2014243988B2 AU 2014243988 A AU2014243988 A AU 2014243988A AU 2014243988 A AU2014243988 A AU 2014243988A AU 2014243988 B2 AU2014243988 B2 AU 2014243988B2
Authority
AU
Australia
Prior art keywords
sensor
pct
rule
tissue
substitute sheet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014243988A
Other languages
English (en)
Other versions
AU2014243988A1 (en
Inventor
Soya Gamsey
Kristen Helton
William Mcmillan
Natalie Wisniewski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Profusa Inc
Original Assignee
Profusa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Profusa Inc filed Critical Profusa Inc
Publication of AU2014243988A1 publication Critical patent/AU2014243988A1/en
Application granted granted Critical
Publication of AU2014243988B2 publication Critical patent/AU2014243988B2/en
Priority to AU2018203993A priority Critical patent/AU2018203993B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0073—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form semi-solid, gel, hydrogel, ointment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/006—Palladium compounds
    • C07F15/0066—Palladium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40—Animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/18—Metal complexes
    • C09K2211/185—Metal complexes of the platinum group, i.e. Os, Ir, Pt, Ru, Rh or Pd
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AU2014243988A 2013-03-14 2014-03-13 Oxygen sensors Active AU2014243988B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2018203993A AU2018203993B2 (en) 2013-03-14 2018-06-06 Oxygen sensors

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784925P 2013-03-14 2013-03-14
US61/784,925 2013-03-14
PCT/US2014/026183 WO2014160258A1 (en) 2013-03-14 2014-03-13 Oxygen sensors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018203993A Division AU2018203993B2 (en) 2013-03-14 2018-06-06 Oxygen sensors

Publications (2)

Publication Number Publication Date
AU2014243988A1 AU2014243988A1 (en) 2015-09-17
AU2014243988B2 true AU2014243988B2 (en) 2018-03-08

Family

ID=51569283

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014243988A Active AU2014243988B2 (en) 2013-03-14 2014-03-13 Oxygen sensors
AU2018203993A Active AU2018203993B2 (en) 2013-03-14 2018-06-06 Oxygen sensors

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2018203993A Active AU2018203993B2 (en) 2013-03-14 2018-06-06 Oxygen sensors

Country Status (8)

Country Link
US (6) US9375494B2 (enExample)
EP (3) EP3488871B1 (enExample)
JP (3) JP6244004B2 (enExample)
CN (2) CN105263936B (enExample)
AU (2) AU2014243988B2 (enExample)
BR (1) BR112015022763A8 (enExample)
CA (1) CA2904127C (enExample)
WO (1) WO2014160258A1 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
KR101690535B1 (ko) 2010-10-06 2017-01-09 프로퓨사 인코퍼레이티드 조직-일체화 센서
WO2014011724A1 (en) * 2012-07-10 2014-01-16 The General Hospital Corporation System and method for monitoring and treating a surface of a subject
JP6244004B2 (ja) 2013-03-14 2017-12-06 プロフサ，インコーポレイテッド 酸素センサ
US10045722B2 (en) 2013-03-14 2018-08-14 Profusa, Inc. Method and device for correcting optical signals
AU2014274784B2 (en) 2013-06-06 2018-12-06 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
JP2017528572A (ja) * 2014-09-15 2017-09-28 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 放射性高分子マトリクス
US10695000B2 (en) * 2015-09-02 2020-06-30 Metronom Health, Inc. Systems and methods for continuous health monitoring using an opto-enzymatic analyte sensor
DE102015014526A1 (de) 2015-11-11 2017-05-11 Giesecke & Devrient Gmbh Sicherheitspigment, lumineszierendes Polymerharz und Verfahren zum Herstellen desselben
WO2017100680A1 (en) * 2015-12-09 2017-06-15 The Texas A&M University System Implantable biosensors
US10324058B2 (en) * 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
WO2017210841A1 (en) * 2016-06-06 2017-12-14 University Of Washington Nanoparticle transducer sensors and methods of use thereof
US10662333B2 (en) 2016-06-17 2020-05-26 Profusa, Inc. NIR long lifetime indicator molecule
EP3500168B1 (en) * 2016-08-22 2021-06-23 Ramot at Tel-Aviv University Ltd. System for subcutaneous bioanalyte sensing
CA3034347A1 (en) 2016-08-22 2018-03-01 Fernando Patolsky Methods and systems for detecting bioanalytes
CN110352036B (zh) 2016-12-21 2022-11-15 普罗菲尤萨股份有限公司 可聚合的近红外染料
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
WO2019006400A1 (en) 2017-06-29 2019-01-03 Profusa, Inc. FABRIC INTEGRATION SENSORS FOR DETECTION OF MULTIPLE ANALYTES
WO2019023093A1 (en) 2017-07-26 2019-01-31 Cardiac Pacemakers, Inc. SYSTEMS AND METHODS FOR POSTURE DISAMBIGULATION
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
CN109864746B (zh) * 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) * 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
US11534503B2 (en) 2017-12-28 2022-12-27 Profusa, Inc. Oxidase-based sensors and methods of using
CA3087231A1 (en) * 2017-12-28 2019-07-04 Profusa, Inc. System and method for analyzing biochemical sensor data
CN112601491B (zh) 2018-06-27 2025-08-19 普罗菲尤萨股份有限公司 近红外葡萄糖传感器
KR20210027392A (ko) 2018-06-29 2021-03-10 프로퓨사 인코퍼레이티드 적층형 센서들 및 사용 방법들
CN109035688B (zh) * 2018-08-06 2021-01-08 山东师范大学 基于磷光的氧浓度声光报警器
WO2020037269A2 (en) * 2018-08-17 2020-02-20 The Regents Of The University Of California Composite matrix for analyte biosensors
GB2577770B (en) * 2019-07-25 2020-10-21 Oxford Optronix Solutions Ltd Method for detection of bacteria
WO2021035047A1 (en) 2019-08-20 2021-02-25 Profusa, Inc. Optical filter device, system, and method for improved optical rejection of out-of-band wavelengths
US11998330B2 (en) * 2021-01-29 2024-06-04 Medtronic Minimed, Inc. Interference rejection membranes useful with analyte sensors
JP7678137B2 (ja) 2021-04-19 2025-05-15 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 電気化学分析物バイオセンサ、関連する組成物ならびにそれらの製造及び使用方法
WO2023172612A2 (en) * 2022-03-08 2023-09-14 Trustees Of Tufts College Silk chromophore composite materials for in situ oxygen sensing
US20250067712A1 (en) * 2023-07-18 2025-02-27 Mohamed Magdy Ibrahim Oxygen Sensing Composition and Method of Use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120265034A1 (en) * 2010-10-06 2012-10-18 Wisniewski Natalie A Tissue-integrating sensors

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5220036A (en) * 1985-12-16 1993-06-15 Polaroid Corporation Thiolactone dye precursors
DK576187D0 (da) 1987-11-03 1987-11-03 Radiometer As Fremgangsmaade til bestemmelse af oxygenkoncentration
US5242835A (en) * 1987-11-03 1993-09-07 Radiometer A/S Method and apparatus for determining the concentration of oxygen
US4925268A (en) 1988-07-25 1990-05-15 Abbott Laboratories Fiber-optic physiological probes
US6362175B1 (en) * 1991-09-20 2002-03-26 The Trustees Of The University Of Pennsylvania Porphyrin compounds for imaging tissue oxygen
JP2533430B2 (ja) 1992-03-24 1996-09-11 三ツ星ベルト株式会社 色素分子を分散させたポリアミド複合物とその製造方法
US5487885A (en) * 1992-12-21 1996-01-30 Biophysica, Inc. Sunblocking polymers and their formulation
US5837865A (en) * 1993-10-15 1998-11-17 Trustees Of The University Of Pennsylvania Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen
JP2883824B2 (ja) 1993-11-07 1999-04-19 科学技術振興事業団 ボロン酸基を有する発蛍光性化合物
JP3321288B2 (ja) 1994-04-25 2002-09-03 日本ペイント株式会社 近赤外光重合性組成物
CA2235738C (en) 1995-11-22 2005-07-26 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
AU3769597A (en) 1996-07-22 1998-02-10 Novartis Ag Process for the preparation of platinum or palladium benzoporphyrins and platinum or palladium cyclohexenoporphyrins, intermediates, and an oxygen sensor comprising platinum or palladium cyclohexenoporphyrin
US6274086B1 (en) * 1996-12-16 2001-08-14 The Trustees Of The University Of Pennsylvania Apparatus for non-invasive imaging oxygen distribution in multi-dimensions
US6485703B1 (en) 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6013122A (en) 1998-08-18 2000-01-11 Option Technologies, Inc. Tattoo inks
KR100753184B1 (ko) 1999-01-25 2007-08-30 내셔날 쥬이쉬 메디칼 앤드 리서치 센터 치환된 포르피린
US6858403B2 (en) 1999-05-11 2005-02-22 M-Biotech, Inc. Polymer matrix containing catalase co-immobilized with analytic enzyme that generates hydrogen peroxide
US6366793B1 (en) 1999-09-10 2002-04-02 Beckman Coulter, Inc. Minimally invasive methods for measuring analtes in vivo
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
CA2415338C (en) 2000-08-04 2012-10-23 Sensors For Medicine And Science, Inc. Detection of analytes in aqueous environments
GB0025147D0 (en) 2000-10-13 2000-11-29 Torsana Diabetes Diagnostics A Optical sensor for in situ measurement of analytes
EP1221465A1 (en) 2001-01-03 2002-07-10 Innosense S.r.l. Symmetric, monofunctionalised polymethine dyes labelling reagents
US20020127626A1 (en) 2001-01-05 2002-09-12 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US6800451B2 (en) 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US20020119581A1 (en) 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes
JP2003261464A (ja) 2002-03-07 2003-09-16 Fuji Photo Film Co Ltd 近赤外蛍光造影剤および蛍光造影法
AU2003220547A1 (en) 2003-03-28 2004-11-23 Terumo Corporation Of Japan Solid-phase saccharide sensing compounds
AU2004233805B2 (en) 2003-04-25 2007-06-21 Kos Life Sciences, Inc. Formation of strong superporous hydrogels
US7358094B2 (en) 2003-05-01 2008-04-15 Bell Michael L Sensor system for saccharides
US7972628B2 (en) 2003-10-01 2011-07-05 University Of Washington Porous biomaterials
WO2005065241A2 (en) 2003-12-24 2005-07-21 Argose, Inc. Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors
AU2005245996A1 (en) 2004-05-21 2005-12-01 Atonomics A/S Surface acoustic wave sensor comprising a hydrogel
DE602005000858T2 (de) 2004-07-23 2008-01-17 Terumo K.K. Saccharid-messender fluoreszierender Monomer, Saccharid-messende fluoreszierende Sensor-Substanz und implantierbarer, Saccharid-messender Sensor
JP4691333B2 (ja) 2004-07-23 2011-06-01 テルモ株式会社 糖類測定用蛍光モノマー化合物、糖類測定用蛍光センサー物質および体内埋め込み用の糖類測定用センサー
JP4691345B2 (ja) 2004-10-07 2011-06-01 テルモ株式会社 糖類測定用蛍光モノマー化合物、糖類測定用蛍光センサー物質および体内埋め込み用の糖類測定用センサー
US20070036682A1 (en) 2005-08-15 2007-02-15 Honeywell International Inc. Microoptic glucose detector
JP5106397B2 (ja) 2005-09-02 2012-12-26 ビセン メディカル， インコーポレイテッド 生体適合性ｎ，ｎ−二置換スルホンアミド含有蛍光色素標識
GB0522796D0 (en) 2005-11-08 2005-12-14 Smart Holograms Ltd Novel boronate complex and its use in a glucose sensor
JP5159778B2 (ja) 2006-07-25 2013-03-13 グルメトリックス，インコーポレイテッド グルコース検知における使用のための蛍光色素
GB0615211D0 (en) 2006-07-31 2006-09-06 Ge Healthcare Uk Ltd Asymmetric flouro-substituted polymethine dyes
DK2099807T3 (da) 2006-11-30 2014-01-27 Senseonics Inc Oxidationsresistente indikatormolekyler
US8785624B2 (en) * 2007-06-13 2014-07-22 University Of Southern California Organic photosensitive optoelectronic devices with nonplanar porphyrins
GB0906318D0 (en) 2009-04-09 2009-05-20 Glysure Ltd Fluorophore and fluorescent sensor compound containing same
US9517023B2 (en) * 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
EP2526103B1 (en) 2010-01-22 2016-05-04 Council of Scientific & Industrial Research A process for the preparation of novel porphyrin derivatives and their use as pdt agents and fluorescence probes
EP2528918B1 (en) 2010-01-29 2014-09-10 Nerviano Medical Sciences S.r.l. 6,7-dihydroimidazo[1,5-a]pyrazin-8(5h)-one derivatives as protein kinase modulators
FR2958557B1 (fr) 2010-04-07 2014-10-31 Centre Nat Rech Scient Procede de traitement d'effluents comprenant des composes halogenes
DE112011101279T5 (de) 2010-04-07 2013-03-14 Cornell University Kovalente organische Gerüste und Verfahren zu deren Herstellung
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
WO2012027593A1 (en) 2010-08-25 2012-03-01 The University Of South Dakota Electron-deficient fluorous porphyrins and methods of making and their use in organic solar cells
EP2614684B1 (en) 2010-09-10 2015-07-01 University Of Southern California Broadly absorbing metalloporphyrin-based multichromophoric arrays for triplet harvesting
EP2658924B1 (en) 2010-12-28 2017-05-10 Dura Chemicals, Inc. Additives for curable liquid compositions
US9250246B2 (en) 2011-06-29 2016-02-02 Portland State University Near-infrared fluorescent dyes with large stokes shifts
WO2013006160A1 (en) 2011-07-01 2013-01-10 Empire Technology Development Llc Paraben derivatives for preserving cellulosic materials
US9469941B2 (en) 2011-07-01 2016-10-18 Empire Technology Development Llc Paraben derivatives for preserving cellulosic materials
WO2013019722A1 (en) 2011-08-01 2013-02-07 Massachusetts Institute Of Technology Photoluminescent nanostructure-based sensors
JP2013103094A (ja) 2011-11-16 2013-05-30 Sony Corp 測定装置、測定方法、プログラム及び記録媒体
US20140072515A9 (en) 2012-03-02 2014-03-13 Greg Hermanson Cyanine compounds
CN102735667B (zh) 2012-06-28 2014-05-21 南京大学 基于氟硼二吡咯-苯硼酸的荧光传感膜及其制备方法和应用
EP2895202A1 (en) 2012-09-13 2015-07-22 Ben-Gurion University Of The Negev Research And Development Authority Diagnostic agents with enhanced sensitivity/specificity
US20140088383A1 (en) 2012-09-14 2014-03-27 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
EP3636653A1 (en) 2013-01-07 2020-04-15 The University of Tokyo Asymmetrical si rhodamine and rhodol synthesis
JP6244004B2 (ja) 2013-03-14 2017-12-06 プロフサ，インコーポレイテッド 酸素センサ
US10045722B2 (en) 2013-03-14 2018-08-14 Profusa, Inc. Method and device for correcting optical signals
US10156573B2 (en) 2013-03-14 2018-12-18 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University Tri-color dual glucose and oxygen sensors and methods of preparing and using them
WO2014152298A1 (en) 2013-03-15 2014-09-25 Promega Corporation New silicon and germanium dyes for use in genetic identity
AU2014274784B2 (en) 2013-06-06 2018-12-06 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
US9410958B2 (en) 2014-03-25 2016-08-09 The Regents Of The University Of California Alkyne-activated fluorogenic azide compounds and methods of use thereof
JP6618486B2 (ja) 2015-01-27 2019-12-11 テルモ株式会社 センサ挿入装置及びセンサ挿入装置セット
BR112017028113A2 (pt) 2015-06-25 2018-08-28 Profusa Inc leitora transcutânea para uso com sensores de analito transplantáveis
CN105602276B (zh) 2016-01-30 2017-07-28 苏州大学 可聚合近红外荧光染料单体及其制备方法、用途
US10662333B2 (en) 2016-06-17 2020-05-26 Profusa, Inc. NIR long lifetime indicator molecule
CN110352036B (zh) 2016-12-21 2022-11-15 普罗菲尤萨股份有限公司 可聚合的近红外染料
JOP20190161A1 (ar) 2016-12-27 2017-06-16 Profusa Inc مستشعرات جلوكوز بطيف قريب من الأشعة تحت الحمراء
MX2019010241A (es) 2017-03-01 2019-12-02 Metronom Health Inc Sensores de analitos y metodos de fabricacion de sensores de analitos.
WO2019006400A1 (en) 2017-06-29 2019-01-03 Profusa, Inc. FABRIC INTEGRATION SENSORS FOR DETECTION OF MULTIPLE ANALYTES
US11534503B2 (en) 2017-12-28 2022-12-27 Profusa, Inc. Oxidase-based sensors and methods of using
CN112601491B (zh) 2018-06-27 2025-08-19 普罗菲尤萨股份有限公司 近红外葡萄糖传感器

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120265034A1 (en) * 2010-10-06 2012-10-18 Wisniewski Natalie A Tissue-integrating sensors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MICHELA QUARANTA ET AL, "Indicators for optical oxygen sensors", BIOANALYTICAL REVIEWS, (20121124), vol. 4, no. 2-4, doi:10.1007/s12566-012-0032-y, ISSN 1867-2086, pages 115 - 157 *
YANQING TIAN ET AL, CHEMISTRY OF MATERIALS, (20100323), vol. 22, no. 6, doi:10.1021/cm903361y, ISSN 0897-4756, pages 2069 - 2078 *

Also Published As

Publication number Publication date
US10874337B2 (en) 2020-12-29
JP6244004B2 (ja) 2017-12-06
BR112015022763A2 (pt) 2017-07-18
JP2016519655A (ja) 2016-07-07
JP2020072650A (ja) 2020-05-14
US20160376501A1 (en) 2016-12-29
US9375494B2 (en) 2016-06-28
US20160374601A1 (en) 2016-12-29
CA2904127C (en) 2023-10-17
CN108852368A (zh) 2018-11-23
JP6923601B2 (ja) 2021-08-25
EP3488871B1 (en) 2020-09-02
US9867560B2 (en) 2018-01-16
AU2018203993A1 (en) 2018-07-12
EP3488871A1 (en) 2019-05-29
JP6628780B2 (ja) 2020-01-15
US9650566B2 (en) 2017-05-16
US20180184956A1 (en) 2018-07-05
BR112015022763A8 (pt) 2019-11-26
EP3797798B1 (en) 2022-09-28
US12048535B2 (en) 2024-07-30
US10383557B2 (en) 2019-08-20
AU2018203993B2 (en) 2020-03-05
CN105263936A (zh) 2016-01-20
EP2970318A1 (en) 2016-01-20
US20140286875A1 (en) 2014-09-25
US20200107762A1 (en) 2020-04-09
CN105263936B (zh) 2018-06-05
AU2014243988A1 (en) 2015-09-17
EP2970318A4 (en) 2016-11-02
EP2970318B1 (en) 2018-11-21
CN108852368B (zh) 2024-01-12
JP2018051333A (ja) 2018-04-05
CA2904127A1 (en) 2014-10-02
EP3797798A1 (en) 2021-03-31
US20210093239A1 (en) 2021-04-01
WO2014160258A1 (en) 2014-10-02

Similar Documents

Publication Publication Date Title
US12048535B2 (en) Oxygen sensors
JP5827999B2 (ja) 組織集積センサー
CN106039401A (zh) 由聚合物‑蛋白质结合物形成的支架，产生该支架的方法及其用途
Roussakis et al. Theranostic biocomposite scaffold membrane
US20200305773A1 (en) Device and method for analyte sensing with microporous annealed particle gels

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)