AU2014236003A1 - Trail enhancers for the selective killing of cancer cells - Google Patents
Trail enhancers for the selective killing of cancer cells Download PDFInfo
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- AU2014236003A1 AU2014236003A1 AU2014236003A AU2014236003A AU2014236003A1 AU 2014236003 A1 AU2014236003 A1 AU 2014236003A1 AU 2014236003 A AU2014236003 A AU 2014236003A AU 2014236003 A AU2014236003 A AU 2014236003A AU 2014236003 A1 AU2014236003 A1 AU 2014236003A1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361803177P | 2013-03-19 | 2013-03-19 | |
| US61/803,177 | 2013-03-19 | ||
| PCT/US2014/031235 WO2014153415A2 (en) | 2013-03-19 | 2014-03-19 | Trail enhancers for the selective killing of cancer cells |
Publications (1)
| Publication Number | Publication Date |
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| AU2014236003A1 true AU2014236003A1 (en) | 2015-11-05 |
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|---|---|---|---|
| AU2014236003A Abandoned AU2014236003A1 (en) | 2013-03-19 | 2014-03-19 | Trail enhancers for the selective killing of cancer cells |
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| US (2) | US9604950B2 (https=) |
| EP (1) | EP2976076B1 (https=) |
| JP (1) | JP6307149B2 (https=) |
| KR (2) | KR101819874B1 (https=) |
| CN (1) | CN105228618A (https=) |
| AU (1) | AU2014236003A1 (https=) |
| CA (1) | CA2907668C (https=) |
| WO (1) | WO2014153415A2 (https=) |
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| EP2976076B1 (en) | 2013-03-19 | 2020-03-04 | The Scripps Research Institute | Trail enhancers for the selective killing of cancer cells |
| US10195177B2 (en) | 2015-10-01 | 2019-02-05 | The University Of Toledo | Use of acyl-homoserine lactone derivatives as anti-thrombotic agents |
| CN105504000B (zh) * | 2016-01-21 | 2019-06-07 | 福建农林大学 | 一种筛选n-酰基高丝氨酸内酯类模拟物的方法 |
| US12329734B2 (en) | 2017-12-19 | 2025-06-17 | Axcess Global Sciences, Llc | Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow |
| US12533346B2 (en) | 2016-04-19 | 2026-01-27 | Axcess Global Sciences, Llc | Administration of berberine metabolites |
| US12599579B2 (en) | 2016-04-19 | 2026-04-14 | Axcess Global Sciences, Llc | Compositions and compounds containing ketone bodies and/or ketone body precursors and one or more amino acids |
| US11026929B2 (en) | 2016-04-19 | 2021-06-08 | Keto Patent Group, Inc. | Administration of berberine metabolites |
| US12109182B2 (en) | 2016-04-19 | 2024-10-08 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate and related compounds in humans |
| US12521378B2 (en) | 2016-04-19 | 2026-01-13 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans |
| US20230346721A1 (en) | 2018-04-18 | 2023-11-02 | Axcess Global Sciences, Llc | Beta-hydroxybutyric acid compositions and methods for delivery of ketone bodies |
| US12496283B2 (en) | 2016-04-19 | 2025-12-16 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate and related compounds in humans |
| EP3666908A1 (en) * | 2016-06-03 | 2020-06-17 | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement | Diet controlled expression of a nucleic acid encoding a pro-apoptotic protein |
| US12171735B2 (en) | 2017-04-19 | 2024-12-24 | Axcess Global Sciences, Llc | Administration of butyrate, beta-hydroxybutyrate, cannabidiol, and related compounds in humans |
| CN110935012A (zh) * | 2019-12-19 | 2020-03-31 | 东北师范大学 | 一种用于治疗肿瘤的药物组合物 |
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| GB9924195D0 (en) * | 1999-10-13 | 1999-12-15 | Univ Nottingham | N-Acyl homoserine lactones for the treatment of cardiac tachyarrhythmias Ischaemic heart disease or congestive heart failure |
| GB0122914D0 (en) * | 2001-09-22 | 2001-11-14 | Univ Nottingham | Modulation of stat activity |
| JP2004231556A (ja) * | 2003-01-29 | 2004-08-19 | Nobuhiko Nomura | アポトーシス誘導剤 |
| WO2004075839A2 (en) * | 2003-02-21 | 2004-09-10 | Irm Llc | Methods and compositions for modulating apoptosis |
| US20070010477A1 (en) * | 2005-04-07 | 2007-01-11 | Dolnick Bruce J | Acyl homoserine lactones for inhibition of cell growth |
| WO2007007207A2 (en) * | 2005-04-13 | 2007-01-18 | Khairia Youssef | Pharmaceutical compositions of 3, 5 -bis (arylidene) -4 -piperidones and analogues there of for modulating cell proliferation |
| GB0610042D0 (en) * | 2006-05-22 | 2006-06-28 | Univ Nottingham | Substituted n-acyl homoserine lactones |
| EP2448930B1 (en) * | 2009-07-03 | 2017-02-15 | The National Institute for Biotechnology in the Negev Ltd. | N-((S)-2-Oxo-tetrahydro-furan-3-yl)-amide derivatives as inhibitors of the bacterial quorum sensing for treating plant or animal diseases and for preventing the formation of biofilms on medical devices |
| EP2976076B1 (en) | 2013-03-19 | 2020-03-04 | The Scripps Research Institute | Trail enhancers for the selective killing of cancer cells |
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2014
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- 2014-03-19 KR KR1020177014484A patent/KR101819874B1/ko not_active Expired - Fee Related
- 2014-03-19 US US14/778,327 patent/US9604950B2/en not_active Expired - Fee Related
- 2014-03-19 KR KR1020157030159A patent/KR101743383B1/ko not_active Expired - Fee Related
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- 2014-03-19 AU AU2014236003A patent/AU2014236003A1/en not_active Abandoned
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2016
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Also Published As
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|---|---|
| KR101819874B1 (ko) | 2018-01-17 |
| US9765061B2 (en) | 2017-09-19 |
| KR101743383B1 (ko) | 2017-06-02 |
| US20160272603A1 (en) | 2016-09-22 |
| CN105228618A (zh) | 2016-01-06 |
| US20170101400A1 (en) | 2017-04-13 |
| US9604950B2 (en) | 2017-03-28 |
| EP2976076A4 (en) | 2016-11-16 |
| EP2976076B1 (en) | 2020-03-04 |
| CA2907668C (en) | 2021-02-23 |
| JP2016515546A (ja) | 2016-05-30 |
| CA2907668A1 (en) | 2014-09-25 |
| WO2014153415A3 (en) | 2015-01-08 |
| JP6307149B2 (ja) | 2018-04-04 |
| WO2014153415A2 (en) | 2014-09-25 |
| KR20150135387A (ko) | 2015-12-02 |
| KR20170063980A (ko) | 2017-06-08 |
| EP2976076A2 (en) | 2016-01-27 |
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