AU2012340670B2 - Cysteamine and/or cystamine for treating ischemic injury - Google Patents
Cysteamine and/or cystamine for treating ischemic injury Download PDFInfo
- Publication number
- AU2012340670B2 AU2012340670B2 AU2012340670A AU2012340670A AU2012340670B2 AU 2012340670 B2 AU2012340670 B2 AU 2012340670B2 AU 2012340670 A AU2012340670 A AU 2012340670A AU 2012340670 A AU2012340670 A AU 2012340670A AU 2012340670 B2 AU2012340670 B2 AU 2012340670B2
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- Prior art keywords
- cysteamine
- cystamine
- subject
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161563034P | 2011-11-22 | 2011-11-22 | |
| US61/563,034 | 2011-11-22 | ||
| PCT/US2012/066288 WO2013078335A1 (en) | 2011-11-22 | 2012-11-21 | Cysteamine and/or cystamine for treating ischemic injury |
Publications (2)
| Publication Number | Publication Date |
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| AU2012340670A1 AU2012340670A1 (en) | 2014-04-17 |
| AU2012340670B2 true AU2012340670B2 (en) | 2016-12-22 |
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| AU2012340670A Ceased AU2012340670B2 (en) | 2011-11-22 | 2012-11-21 | Cysteamine and/or cystamine for treating ischemic injury |
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| EP (1) | EP2782564B1 (https=) |
| JP (1) | JP6411215B2 (https=) |
| KR (1) | KR20140097132A (https=) |
| CN (2) | CN103974698A (https=) |
| AU (1) | AU2012340670B2 (https=) |
| BR (1) | BR112014012167A2 (https=) |
| CA (1) | CA2851387A1 (https=) |
| HK (1) | HK1202440A1 (https=) |
| IL (1) | IL232608A0 (https=) |
| MX (1) | MX2014004469A (https=) |
| MY (1) | MY165953A (https=) |
| RU (1) | RU2638807C2 (https=) |
| SG (2) | SG11201402472QA (https=) |
| WO (1) | WO2013078335A1 (https=) |
| ZA (1) | ZA201402290B (https=) |
Families Citing this family (7)
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| TWI649100B (zh) * | 2013-06-17 | 2019-02-01 | 地平線罕見醫學製藥有限責任公司 | 延遲釋放型半胱胺珠粒調配物，以及其製備及使用方法 |
| WO2017004485A1 (en) * | 2015-07-02 | 2017-01-05 | Raptor Pharmaceuticals Inc. | Ado-resistant cysteamine analogs and uses thereof |
| CN106591461A (zh) * | 2016-12-29 | 2017-04-26 | 天津协和华美医学诊断技术有限公司 | 一种检测遗传性易栓症相关基因群的检测试剂盒 |
| KR20190119046A (ko) | 2017-01-19 | 2019-10-21 | 오톨로직 파마슈틱스, 인크. | N-아세틸시스테인의 제제 및 이의 용도 |
| WO2018140594A1 (en) * | 2017-01-25 | 2018-08-02 | Adare Pharmaceuticals, Inc. | Cysteamine prodrugs |
| US12576051B2 (en) | 2019-07-30 | 2026-03-17 | The Regents Of The University Of California | Methods and composition for treating respiratory obstructive diseases |
| CN113484453B (zh) * | 2021-07-07 | 2022-08-09 | 天津中医药大学 | 一种缺血性脑卒中预警方法 |
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| US2809918A (en) | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| DE2010416B2 (de) | 1970-03-05 | 1979-03-29 | Hoechst Ag, 6000 Frankfurt | Oral anwendbare Arzneiform mit Retardwirkung |
| FR2471186A1 (fr) | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
| US4301146A (en) | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
| FR2549051B1 (fr) | 1983-06-22 | 1986-05-16 | Centre Nat Rech Scient | Nouveaux agents radioprotecteurs ayant une structure amino-thioalkyle et procede pour leur preparation |
| FR2573077B1 (fr) * | 1984-11-13 | 1987-02-13 | Sanofi Sa | Nouveaux derives thiosulfonates, leur procede de preparation ainsi que les compositions pharmaceutiques les contenant |
| US4728512A (en) | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| US4794001A (en) | 1986-03-04 | 1988-12-27 | American Home Products Corporation | Formulations providing three distinct releases |
| EP0306937A3 (en) * | 1987-09-08 | 1990-07-25 | The Green Cross Corporation | Platelet agglutination-inhibiting agent |
| JPH02243619A (ja) * | 1989-03-15 | 1990-09-27 | Green Cross Corp:The | 抗血小板凝集剤 |
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| ZA9610745B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| US6087398A (en) * | 1996-03-01 | 2000-07-11 | South Alabama Medical Science Foundation | Sickle cell anemia treatment |
| FR2753098B1 (fr) * | 1996-09-06 | 1998-11-27 | Sod Conseils Rech Applic | Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene |
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| PE20000728A1 (es) | 1998-06-26 | 2000-08-21 | Cocensys Inc | Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda |
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| US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
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| EP1235572A2 (en) | 1999-10-29 | 2002-09-04 | MERCK SHARP & DOHME LTD. | Method to treat pain utilizing benzimidazole nmda/nr2b antagonists |
| US6432976B1 (en) | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
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| US7442720B2 (en) * | 2003-12-19 | 2008-10-28 | Omega Bio-Pharma (I.P.3) Limited | Compositions and methods for treating diabetes |
| KR20070005738A (ko) * | 2004-05-03 | 2007-01-10 | 오메가 바이오 파마(아이.피.3) 리미티드 | 콜레스테롤 과잉혈증 및 당뇨병의 합병증을 치료하기 위한시스테아민 |
| EP2636404B1 (en) * | 2007-11-30 | 2019-03-20 | The Regents of The University of California | Methods of Treating Non-Alcoholic Steatohepatitis (Nash) Using Cysteamine Products |
| RU2428192C1 (ru) * | 2010-06-10 | 2011-09-10 | Войсковая Часть 41598 | Радиозащитное средство |
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2012
- 2012-11-21 MX MX2014004469A patent/MX2014004469A/es unknown
- 2012-11-21 CA CA2851387A patent/CA2851387A1/en not_active Abandoned
- 2012-11-21 EP EP12798116.5A patent/EP2782564B1/en not_active Not-in-force
- 2012-11-21 KR KR1020147010492A patent/KR20140097132A/ko not_active Ceased
- 2012-11-21 HK HK15103104.0A patent/HK1202440A1/xx unknown
- 2012-11-21 MY MYPI2014001446A patent/MY165953A/en unknown
- 2012-11-21 WO PCT/US2012/066288 patent/WO2013078335A1/en not_active Ceased
- 2012-11-21 JP JP2014542590A patent/JP6411215B2/ja not_active Expired - Fee Related
- 2012-11-21 BR BR112014012167A patent/BR112014012167A2/pt not_active IP Right Cessation
- 2012-11-21 SG SG11201402472QA patent/SG11201402472QA/en unknown
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- 2012-11-21 AU AU2012340670A patent/AU2012340670B2/en not_active Ceased
- 2012-11-21 CN CN201810067673.7A patent/CN108042517A/zh active Pending
- 2012-11-21 US US14/360,095 patent/US20140322315A1/en not_active Abandoned
- 2012-11-21 RU RU2014125282A patent/RU2638807C2/ru not_active IP Right Cessation
- 2012-11-21 SG SG10201800159QA patent/SG10201800159QA/en unknown
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- 2014-03-27 ZA ZA2014/02290A patent/ZA201402290B/en unknown
- 2014-05-14 IL IL232608A patent/IL232608A0/en unknown
Also Published As
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| HK1202440A1 (zh) | 2015-10-02 |
| SG10201800159QA (en) | 2018-02-27 |
| IL232608A0 (en) | 2014-06-30 |
| WO2013078335A1 (en) | 2013-05-30 |
| JP2014533701A (ja) | 2014-12-15 |
| ZA201402290B (en) | 2017-06-28 |
| JP6411215B2 (ja) | 2018-10-24 |
| CA2851387A1 (en) | 2013-05-30 |
| CN103974698A (zh) | 2014-08-06 |
| CN108042517A (zh) | 2018-05-18 |
| RU2014125282A (ru) | 2015-12-27 |
| MY165953A (en) | 2018-05-18 |
| RU2638807C2 (ru) | 2017-12-15 |
| EP2782564A1 (en) | 2014-10-01 |
| EP2782564B1 (en) | 2019-01-09 |
| SG11201402472QA (en) | 2014-06-27 |
| AU2012340670A1 (en) | 2014-04-17 |
| BR112014012167A2 (pt) | 2017-05-30 |
| KR20140097132A (ko) | 2014-08-06 |
| MX2014004469A (es) | 2014-08-01 |
| US20140322315A1 (en) | 2014-10-30 |
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