AU2012335280B2 - Process for the preparation of beta-C-aryl glucosides - Google Patents
Process for the preparation of beta-C-aryl glucosides Download PDFInfo
- Publication number
- AU2012335280B2 AU2012335280B2 AU2012335280A AU2012335280A AU2012335280B2 AU 2012335280 B2 AU2012335280 B2 AU 2012335280B2 AU 2012335280 A AU2012335280 A AU 2012335280A AU 2012335280 A AU2012335280 A AU 2012335280A AU 2012335280 B2 AU2012335280 B2 AU 2012335280B2
- Authority
- AU
- Australia
- Prior art keywords
- formula
- compound
- process according
- group
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556780P | 2011-11-07 | 2011-11-07 | |
| US61/556,780 | 2011-11-07 | ||
| US201261661793P | 2012-06-19 | 2012-06-19 | |
| US61/661,793 | 2012-06-19 | ||
| PCT/IB2012/002894 WO2013068850A2 (en) | 2011-11-07 | 2012-11-07 | PROCESS FOR THE PREPARATION OF β-C-ARYL GLUCOSIDES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012335280A1 AU2012335280A1 (en) | 2014-05-22 |
| AU2012335280B2 true AU2012335280B2 (en) | 2016-09-29 |
Family
ID=48290709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012335280A Ceased AU2012335280B2 (en) | 2011-11-07 | 2012-11-07 | Process for the preparation of beta-C-aryl glucosides |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP2776449B1 (enExample) |
| JP (1) | JP6144686B2 (enExample) |
| KR (1) | KR101756772B1 (enExample) |
| CN (1) | CN103974964B (enExample) |
| AU (1) | AU2012335280B2 (enExample) |
| BR (1) | BR112014010997A2 (enExample) |
| CA (1) | CA2854591A1 (enExample) |
| IL (1) | IL232418A (enExample) |
| IN (1) | IN2014CN04050A (enExample) |
| TW (1) | TWI488861B (enExample) |
| WO (1) | WO2013068850A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104557894A (zh) * | 2013-10-18 | 2015-04-29 | 上海信谊药厂有限公司 | 坎格列汀晶型及其制备方法 |
| WO2015155739A1 (en) * | 2014-04-11 | 2015-10-15 | Scinopharm Taiwan, Ltd. | Process for the preparation of beta-c-arylglucosides |
| CN105017237A (zh) * | 2014-04-29 | 2015-11-04 | 嘉实（湖南）医药科技有限公司 | 一种卡格列净的制备工艺 |
| EP2947077A1 (en) | 2014-05-19 | 2015-11-25 | LEK Pharmaceuticals d.d. | Stereoselective synthesis of intermediates in the preparation of ß-C-arylglucosides |
| WO2017046655A1 (en) | 2015-09-16 | 2017-03-23 | Optimus Drugs (P) Ltd | A novel process for the preparation of canagliflozin |
| CN105294624B (zh) * | 2015-11-16 | 2018-01-12 | 山东罗欣药业集团股份有限公司 | 一种达格列净的制备方法 |
| CN105486767B (zh) * | 2015-12-03 | 2018-03-13 | 上海应用技术学院 | 一种达格列净及其α‑异构体的分离方法 |
| CN105541815B (zh) * | 2015-12-24 | 2018-07-13 | 寿光富康制药有限公司 | 一种卡格列净的制备方法 |
| EP4114365A1 (en) | 2020-03-05 | 2023-01-11 | KRKA, d.d., Novo mesto | Pharmaceutical composition comprising sglt2 inhibitor |
| CN115867538A (zh) | 2020-06-05 | 2023-03-28 | 新梅斯托克公司 | 高纯的无定形达格列净的制备 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7847074B2 (en) * | 2005-09-15 | 2010-12-07 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted (ethynyl-benzyl)-benzene derivatives and intermediates thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5872599A (ja) * | 1981-10-27 | 1983-04-30 | Kanto Ishi Pharma Co Ltd | 複合糖質誘導体 |
| PL378324A1 (pl) * | 2003-01-03 | 2006-03-20 | Bristol-Myers Squibb Company | Sposób wytwarzania C-aryloglukozydowych inhibitorów SGLT2 |
| CN102762583A (zh) | 2009-11-24 | 2012-10-31 | 南非医学研究院 | 合成阿司巴汀及其类似物的方法 |
-
2012
- 2012-11-07 JP JP2014539427A patent/JP6144686B2/ja not_active Expired - Fee Related
- 2012-11-07 CA CA2854591A patent/CA2854591A1/en not_active Abandoned
- 2012-11-07 EP EP12847376.6A patent/EP2776449B1/en not_active Not-in-force
- 2012-11-07 BR BR112014010997A patent/BR112014010997A2/pt not_active Application Discontinuation
- 2012-11-07 KR KR1020147015420A patent/KR101756772B1/ko not_active Expired - Fee Related
- 2012-11-07 IN IN4050CHN2014 patent/IN2014CN04050A/en unknown
- 2012-11-07 WO PCT/IB2012/002894 patent/WO2013068850A2/en not_active Ceased
- 2012-11-07 TW TW101141390A patent/TWI488861B/zh not_active IP Right Cessation
- 2012-11-07 AU AU2012335280A patent/AU2012335280B2/en not_active Ceased
- 2012-11-07 CN CN201280054691.2A patent/CN103974964B/zh not_active Expired - Fee Related
-
2014
- 2014-05-01 IL IL232418A patent/IL232418A/en not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7847074B2 (en) * | 2005-09-15 | 2010-12-07 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted (ethynyl-benzyl)-benzene derivatives and intermediates thereof |
Non-Patent Citations (1)
| Title |
|---|
| OGURA H. et al, Nucleic Acid Chem., 1991, 4, 109-112 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013068850A2 (en) | 2013-05-16 |
| KR101756772B1 (ko) | 2017-07-26 |
| KR20140089427A (ko) | 2014-07-14 |
| CA2854591A1 (en) | 2013-05-16 |
| IL232418A (en) | 2016-10-31 |
| AU2012335280A1 (en) | 2014-05-22 |
| BR112014010997A2 (pt) | 2017-06-06 |
| CN103974964B (zh) | 2016-03-23 |
| TWI488861B (zh) | 2015-06-21 |
| EP2776449A4 (en) | 2015-10-07 |
| WO2013068850A8 (en) | 2013-10-10 |
| EP2776449A2 (en) | 2014-09-17 |
| CN103974964A (zh) | 2014-08-06 |
| TW201335175A (zh) | 2013-09-01 |
| IL232418A0 (en) | 2014-06-30 |
| EP2776449B1 (en) | 2017-08-02 |
| WO2013068850A3 (en) | 2013-08-22 |
| IN2014CN04050A (enExample) | 2015-07-10 |
| JP6144686B2 (ja) | 2017-06-07 |
| JP2014532690A (ja) | 2014-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2776449B1 (en) | Process for the preparation of beta-c-aryl glucosides | |
| CA2592995C (en) | 1-thio-d-glucitol derivatives | |
| JP4809931B2 (ja) | ベンジルベンゼン誘導体およびその使用方法 | |
| JP4834080B2 (ja) | グルコピラノシル置換ベンジル−ベンゼン誘導体の調製方法及びこれらの方法における中間体 | |
| JP6105489B2 (ja) | アリールグルコシド化合物、その調製方法及び使用 | |
| TWI254635B (en) | Azulene derivative and salt thereof | |
| CA2730734C (en) | Deuterated 2,3,4-trihydroxy-tetrahydropyranyl-benzylbenzene compounds having sodium glucose cotransporter inhibitory activity | |
| US8952139B2 (en) | Process for the preparation of β-C-aryl glucosides | |
| CN101495495A (zh) | 取代螺缩酮衍生物、及其作为糖尿病治疗药的应用 | |
| JP6259814B2 (ja) | 新規なヒドロキサム酸誘導体またはその塩 | |
| CN107108539A (zh) | 钠‑葡萄糖协同转运蛋白2(sglt‑2)抑制剂 | |
| TW202039428A (zh) | Ｃ－芳基羥基二醇化物（Ｃ－Ａｒｙｌｈｙｄｒｏｘｙｇｌｙｃｏｘｉｄｅ）衍生物之製造方法 | |
| EP4249462A1 (en) | Method for producing ketone derivative | |
| CN109096270A (zh) | 一种卡格列净4-位异构体杂质及其制备方法 | |
| CN109553649B (zh) | 一种卡格列净中间体的制备方法 | |
| CN109111490A (zh) | 卤代新戊酰基吡喃葡萄糖及其用于sglt2抑制剂的制备方法 | |
| HK1155328B (en) | Deuterated benzylbenzene derivatives and methods of use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |