AU2012264589B2 - Polycistronic expression system for bacteria - Google Patents

Polycistronic expression system for bacteria Download PDF

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Publication number
AU2012264589B2
AU2012264589B2 AU2012264589A AU2012264589A AU2012264589B2 AU 2012264589 B2 AU2012264589 B2 AU 2012264589B2 AU 2012264589 A AU2012264589 A AU 2012264589A AU 2012264589 A AU2012264589 A AU 2012264589A AU 2012264589 B2 AU2012264589 B2 AU 2012264589B2
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gram
gene
positive bacterium
endogenous
promoter
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AU2012264589A
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AU2012264589A1 (en
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Lothar Steidler
Karolien Van Huynegem
Klaas Vandenbroucke
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Intrexon Actobiotics NV
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Intrexon Actobiotics NV
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    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)

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AU2012264589A 2011-06-01 2012-06-01 Polycistronic expression system for bacteria Ceased AU2012264589B2 (en)

Priority Applications (1)

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AU2017203281A AU2017203281B2 (en) 2011-06-01 2017-05-16 Polycistronic expression system for bacteria

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EP11168495.7 2011-06-01
EP11168495 2011-06-01
EP11173588 2011-07-12
EP11173588.2 2011-07-12
PCT/EP2012/060431 WO2012164083A1 (en) 2011-06-01 2012-06-01 Polycistronic expression system for bacteria

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AU2012264589B2 true AU2012264589B2 (en) 2017-02-16

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US (3) US9920324B2 (cg-RX-API-DMAC10.html)
EP (2) EP2714912B1 (cg-RX-API-DMAC10.html)
JP (3) JP6175428B2 (cg-RX-API-DMAC10.html)
KR (1) KR102066292B1 (cg-RX-API-DMAC10.html)
CN (2) CN103562390B (cg-RX-API-DMAC10.html)
AU (2) AU2012264589B2 (cg-RX-API-DMAC10.html)
BR (1) BR112013030824A8 (cg-RX-API-DMAC10.html)
CA (2) CA2837634C (cg-RX-API-DMAC10.html)
DK (1) DK2714912T3 (cg-RX-API-DMAC10.html)
ES (1) ES2676877T3 (cg-RX-API-DMAC10.html)
HU (1) HUE039577T2 (cg-RX-API-DMAC10.html)
RU (2) RU2644346C2 (cg-RX-API-DMAC10.html)
WO (1) WO2012164083A1 (cg-RX-API-DMAC10.html)

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US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP7292877B2 (ja) 2016-01-14 2023-06-19 イントレクソン・アクトバイオテイクス・エヌブイ １型糖尿病を処置するための組成物および方法
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US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
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