AU2012234323A1 - Otamixaban formulations with improved stability - Google Patents
Otamixaban formulations with improved stability Download PDFInfo
- Publication number
- AU2012234323A1 AU2012234323A1 AU2012234323A AU2012234323A AU2012234323A1 AU 2012234323 A1 AU2012234323 A1 AU 2012234323A1 AU 2012234323 A AU2012234323 A AU 2012234323A AU 2012234323 A AU2012234323 A AU 2012234323A AU 2012234323 A1 AU2012234323 A1 AU 2012234323A1
- Authority
- AU
- Australia
- Prior art keywords
- acid
- pharmaceutical composition
- amino
- methyl
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000000203 mixture Substances 0.000 title claims abstract description 44
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract description 20
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Landscapes
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Applications Claiming Priority (5)
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| EP11305347.4 | 2011-03-29 | ||
| EP11305347 | 2011-03-29 | ||
| US201161499941P | 2011-06-22 | 2011-06-22 | |
| US61/499,941 | 2011-06-22 | ||
| PCT/EP2012/055361 WO2012130819A1 (en) | 2011-03-29 | 2012-03-27 | Otamixaban formulations with improved stability |
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| AU2012234323A1 true AU2012234323A1 (en) | 2013-10-17 |
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| EP (1) | EP2691075A1 (https=) |
| JP (1) | JP5993933B2 (https=) |
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| CN (1) | CN103561723B (https=) |
| AR (1) | AR085580A1 (https=) |
| AU (1) | AU2012234323A1 (https=) |
| BR (1) | BR112013024801A2 (https=) |
| CA (1) | CA2830962C (https=) |
| CO (1) | CO6801755A2 (https=) |
| EA (1) | EA025572B1 (https=) |
| IL (1) | IL228573A (https=) |
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| PH (1) | PH12013501991A1 (https=) |
| SG (1) | SG193932A1 (https=) |
| UY (1) | UY33975A (https=) |
| WO (1) | WO2012130819A1 (https=) |
| ZA (1) | ZA201308061B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2691075A1 (en) | 2011-03-29 | 2014-02-05 | Sanofi | Otamixaban formulations with improved stability |
| KR102295748B1 (ko) | 2013-01-31 | 2021-09-01 | 버텍스 파마슈티칼스 인코포레이티드 | 나트륨 채널의 조절제로서의 피리돈 아미드 |
| DE102013212933B3 (de) * | 2013-07-03 | 2014-11-27 | Schaeffler Technologies Gmbh & Co. Kg | Lageranordnung in einem Elektromotor |
| DK3668516T3 (da) | 2017-08-16 | 2021-12-13 | Merck Patent Gmbh | Stabile lyofilisater omfattende 5,10-methylen-(6r)-tetrahydrofolsyre og en dicarboxylsyre |
| CN109010273B (zh) * | 2018-10-08 | 2021-03-19 | 中国药科大学 | 一种阿哌沙班纳米混悬剂及其制备方法 |
| CN113384526A (zh) * | 2021-08-03 | 2021-09-14 | 合肥医工医药股份有限公司 | 一种稳定的阿哌沙班口服溶液制剂及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3030272A (en) * | 1960-05-26 | 1962-04-17 | Abbott Lab | Stable heaparin solution |
| ES2224200T3 (es) | 1992-11-27 | 2005-03-01 | Mayne Pharma (Usa) Inc. | Composicion inyectable estable de paclitaxel. |
| US6080767A (en) | 1996-01-02 | 2000-06-27 | Aventis Pharmaceuticals Products Inc. | Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides |
| DK0906094T3 (da) | 1996-01-02 | 2003-10-20 | Aventis Pharma Inc | Substituerede N-[(aminoiminomethyl- eller aminomethyl)phenyl]propylamider |
| GB0108903D0 (en) * | 2000-10-05 | 2001-05-30 | Aventis Pharm Prod Inc | Novel crystalline forms of a factor Xa inhibitor |
| US20050059719A1 (en) * | 2003-09-16 | 2005-03-17 | Badawy Sherif Ibrahim Farag | Solid dosage formulation containing a Factor Xa inhibitor and method |
| FR2863891B1 (fr) * | 2003-12-23 | 2006-03-24 | Pf Medicament | Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation |
| NZ597957A (en) * | 2009-07-29 | 2014-05-30 | Sanofi Sa | Otamixaban for treatment of elderly and renal impaired non-st elevation myocardial infarction patients |
| EP2691075A1 (en) | 2011-03-29 | 2014-02-05 | Sanofi | Otamixaban formulations with improved stability |
| ES2539236T3 (es) | 2011-03-29 | 2015-06-29 | Sanofi | Sal de ácido benzoico de Otamixaban |
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2012
- 2012-03-27 EP EP12710516.1A patent/EP2691075A1/en not_active Withdrawn
- 2012-03-27 AR ARP120101016A patent/AR085580A1/es unknown
- 2012-03-27 US US13/431,571 patent/US20120252852A1/en not_active Abandoned
- 2012-03-27 MX MX2013011260A patent/MX342324B/es active IP Right Grant
- 2012-03-27 AU AU2012234323A patent/AU2012234323A1/en not_active Abandoned
- 2012-03-27 UY UY0001033975A patent/UY33975A/es not_active Application Discontinuation
- 2012-03-27 JP JP2014501567A patent/JP5993933B2/ja not_active Expired - Fee Related
- 2012-03-27 SG SG2013071352A patent/SG193932A1/en unknown
- 2012-03-27 CA CA2830962A patent/CA2830962C/en not_active Expired - Fee Related
- 2012-03-27 BR BR112013024801A patent/BR112013024801A2/pt not_active Application Discontinuation
- 2012-03-27 CN CN201280026572.6A patent/CN103561723B/zh not_active Expired - Fee Related
- 2012-03-27 EA EA201391406A patent/EA025572B1/ru not_active IP Right Cessation
- 2012-03-27 US US14/008,343 patent/US20140018398A1/en not_active Abandoned
- 2012-03-27 PH PH1/2013/501991A patent/PH12013501991A1/en unknown
- 2012-03-27 MA MA36345A patent/MA35050B1/fr unknown
- 2012-03-27 WO PCT/EP2012/055361 patent/WO2012130819A1/en not_active Ceased
- 2012-03-27 KR KR1020137028419A patent/KR101844623B1/ko not_active Expired - Fee Related
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2013
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- 2013-10-23 CO CO13251310A patent/CO6801755A2/es unknown
- 2013-10-29 ZA ZA2013/08061A patent/ZA201308061B/en unknown
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2016
- 2016-09-14 US US15/265,191 patent/US9993464B2/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| PH12013501991A1 (en) | 2013-11-25 |
| KR20140019818A (ko) | 2014-02-17 |
| KR101844623B1 (ko) | 2018-04-02 |
| US20140018398A1 (en) | 2014-01-16 |
| CO6801755A2 (es) | 2013-11-29 |
| SG193932A1 (en) | 2013-11-29 |
| US20170224668A1 (en) | 2017-08-10 |
| AR085580A1 (es) | 2013-10-09 |
| MA35050B1 (fr) | 2014-04-03 |
| EA201391406A1 (ru) | 2014-02-28 |
| NZ616180A (en) | 2015-10-30 |
| MX342324B (es) | 2016-09-23 |
| US9993464B2 (en) | 2018-06-12 |
| CN103561723B (zh) | 2016-04-20 |
| EP2691075A1 (en) | 2014-02-05 |
| JP5993933B2 (ja) | 2016-09-14 |
| US20120252852A1 (en) | 2012-10-04 |
| CN103561723A (zh) | 2014-02-05 |
| CA2830962C (en) | 2019-06-18 |
| IL228573A0 (en) | 2013-12-31 |
| EA025572B1 (ru) | 2017-01-30 |
| UY33975A (es) | 2012-10-31 |
| IL228573A (en) | 2017-12-31 |
| BR112013024801A2 (pt) | 2016-12-20 |
| WO2012130819A1 (en) | 2012-10-04 |
| CA2830962A1 (en) | 2012-10-04 |
| JP2014509621A (ja) | 2014-04-21 |
| MX2013011260A (es) | 2014-03-27 |
| ZA201308061B (en) | 2015-01-28 |
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