AU2012222963B2 - Two phase immiscible system for the pretreatment of embedded biological samples - Google Patents

Two phase immiscible system for the pretreatment of embedded biological samples Download PDF

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Publication number
AU2012222963B2
AU2012222963B2 AU2012222963A AU2012222963A AU2012222963B2 AU 2012222963 B2 AU2012222963 B2 AU 2012222963B2 AU 2012222963 A AU2012222963 A AU 2012222963A AU 2012222963 A AU2012222963 A AU 2012222963A AU 2012222963 B2 AU2012222963 B2 AU 2012222963B2
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Australia
Prior art keywords
carrier composition
biological sample
pretreatment
reagent
pretreatment container
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AU2012222963A
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AU2012222963A1 (en
Inventor
Steen Hauge Matthiesen
Soren Nielsen
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Agilent Technologies Inc
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Agilent Technologies Inc
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Application filed by Agilent Technologies Inc filed Critical Agilent Technologies Inc
Publication of AU2012222963A1 publication Critical patent/AU2012222963A1/en
Priority to AU2016222358A priority Critical patent/AU2016222358A1/en
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Priority to AU2018250513A priority patent/AU2018250513B2/en
Assigned to AGILENT TECHNOLOGIES, INC. reassignment AGILENT TECHNOLOGIES, INC. Request for Assignment Assignors: DAKO DENMARK A/S
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G01N2001/366—Moulds; Demoulding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2012222963A 2011-02-28 2012-02-28 Two phase immiscible system for the pretreatment of embedded biological samples Active AU2012222963B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2016222358A AU2016222358A1 (en) 2011-02-28 2016-08-30 Two phase immiscible system for the pretreatment of embedded biological samples
AU2018250513A AU2018250513B2 (en) 2011-02-28 2018-10-19 Two phase immiscible system for the pretreatment of embedded biological samples

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161447364P 2011-02-28 2011-02-28
US61/447,364 2011-02-28
PCT/IB2012/000405 WO2012117294A2 (en) 2011-02-28 2012-02-28 Two phase immiscible system for the pretreatment of embedded biological samples

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016222358A Division AU2016222358A1 (en) 2011-02-28 2016-08-30 Two phase immiscible system for the pretreatment of embedded biological samples

Publications (2)

Publication Number Publication Date
AU2012222963A1 AU2012222963A1 (en) 2013-08-22
AU2012222963B2 true AU2012222963B2 (en) 2016-09-22

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ID=46758338

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2012222963A Active AU2012222963B2 (en) 2011-02-28 2012-02-28 Two phase immiscible system for the pretreatment of embedded biological samples
AU2016222358A Abandoned AU2016222358A1 (en) 2011-02-28 2016-08-30 Two phase immiscible system for the pretreatment of embedded biological samples
AU2018250513A Active AU2018250513B2 (en) 2011-02-28 2018-10-19 Two phase immiscible system for the pretreatment of embedded biological samples

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2016222358A Abandoned AU2016222358A1 (en) 2011-02-28 2016-08-30 Two phase immiscible system for the pretreatment of embedded biological samples
AU2018250513A Active AU2018250513B2 (en) 2011-02-28 2018-10-19 Two phase immiscible system for the pretreatment of embedded biological samples

Country Status (7)

Country Link
US (1) US10295442B2 (cg-RX-API-DMAC7.html)
EP (1) EP2686662B1 (cg-RX-API-DMAC7.html)
JP (1) JP6013376B2 (cg-RX-API-DMAC7.html)
CN (2) CN103930761B (cg-RX-API-DMAC7.html)
AU (3) AU2012222963B2 (cg-RX-API-DMAC7.html)
CA (1) CA2826056C (cg-RX-API-DMAC7.html)
WO (1) WO2012117294A2 (cg-RX-API-DMAC7.html)

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US10379015B2 (en) 2017-06-04 2019-08-13 Diagnostic Biosystems Method for labeling concentration density differentials of an analyte in a biological sample
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CN109142012A (zh) * 2018-08-17 2019-01-04 上海迈景纳米科技有限公司 一种ffpe样本快速脱蜡装置及其使用方法
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CN110132673B (zh) * 2019-05-22 2021-06-15 上海市农业科学院 一种制备金针菇子实体组织切片的方法
CN112113822A (zh) * 2019-06-21 2020-12-22 深圳迈瑞生物医疗电子股份有限公司 生物样本染色装置、推片染色机及生物样本染色方法
CN111238912A (zh) * 2020-03-12 2020-06-05 河南农业大学 一种叶片切片包埋的方法和叶片制片方法
EP4193137A4 (en) * 2020-08-10 2024-05-22 Leica Biosystems Nussloch GmbH Xylene-free tissue processor and method for processing tissue
US12496582B2 (en) 2020-09-10 2025-12-16 Instapath, Inc. Systems for delivery of a liquid to and removal of a liquid from a sample
CN113092219B (zh) * 2021-03-24 2025-07-18 迪帕微(上海)生物科技有限公司 一种硬组织切片防脱预处理装置及防脱预处理方法
US20230392196A1 (en) * 2022-06-06 2023-12-07 Applied Materials, Inc. RNA retrieval process for preparing formalin-fixed, paraffin-embedded (FFPE) tissue samples for in situ hybridization

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Also Published As

Publication number Publication date
EP2686662A2 (en) 2014-01-22
US20140051118A1 (en) 2014-02-20
US10295442B2 (en) 2019-05-21
CN107255584B (zh) 2021-04-13
JP2014523514A (ja) 2014-09-11
CA2826056C (en) 2021-01-26
EP2686662A4 (en) 2017-07-26
CN103930761B (zh) 2017-06-13
AU2012222963A1 (en) 2013-08-22
CN103930761A (zh) 2014-07-16
JP6013376B2 (ja) 2016-10-25
CN107255584A (zh) 2017-10-17
AU2018250513A1 (en) 2018-11-15
WO2012117294A3 (en) 2016-07-28
WO2012117294A2 (en) 2012-09-07
AU2016222358A1 (en) 2016-09-22
AU2018250513B2 (en) 2020-05-21
EP2686662B1 (en) 2022-01-19
CA2826056A1 (en) 2012-09-07

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