AU2011349524B2 - Quinoxalines and aza-quinoxalines as CRTH2 receptor modulators - Google Patents
Quinoxalines and aza-quinoxalines as CRTH2 receptor modulators Download PDFInfo
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- AU2011349524B2 AU2011349524B2 AU2011349524A AU2011349524A AU2011349524B2 AU 2011349524 B2 AU2011349524 B2 AU 2011349524B2 AU 2011349524 A AU2011349524 A AU 2011349524A AU 2011349524 A AU2011349524 A AU 2011349524A AU 2011349524 B2 AU2011349524 B2 AU 2011349524B2
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- phenyl
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- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- Immunology (AREA)
- Otolaryngology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061426886P | 2010-12-23 | 2010-12-23 | |
| US61/426,886 | 2010-12-23 | ||
| PCT/US2011/065716 WO2012087861A1 (en) | 2010-12-23 | 2011-12-19 | Quinoxalines and aza-quinoxalines as crth2 receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2011349524A1 AU2011349524A1 (en) | 2013-05-30 |
| AU2011349524B2 true AU2011349524B2 (en) | 2016-06-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2011349524A Ceased AU2011349524B2 (en) | 2010-12-23 | 2011-12-19 | Quinoxalines and aza-quinoxalines as CRTH2 receptor modulators |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9469615B2 (enExample) |
| EP (1) | EP2661428B1 (enExample) |
| JP (1) | JP5952829B2 (enExample) |
| KR (1) | KR20130133219A (enExample) |
| CN (1) | CN103702985B (enExample) |
| AR (1) | AR084573A1 (enExample) |
| AU (1) | AU2011349524B2 (enExample) |
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| WO2012087872A1 (en) | 2010-12-23 | 2012-06-28 | Merck Sharp & Dohme Corp. | Quinolines and aza-quinolines as crth2 receptor modulators |
| CN103459382B (zh) * | 2011-03-02 | 2016-06-29 | 拜奥埃内杰尼克斯公司 | 用于抑制pask的杂环化合物 |
| EA025100B1 (ru) | 2011-06-17 | 2016-11-30 | Мерк Шарп И Доум Корп. | Циклоалкил-конденсированные тетрагидрохинолины в качестве модуляторов рецепторов crth |
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| MX361539B (es) | 2012-04-25 | 2018-12-10 | Takeda Pharmaceuticals Co | Compuesto heterociclico nitrogenado. |
| US9169270B2 (en) | 2012-07-05 | 2015-10-27 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| WO2014010732A1 (ja) | 2012-07-13 | 2014-01-16 | 武田薬品工業株式会社 | 複素環化合物 |
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| EP3126005A4 (en) | 2014-03-31 | 2017-11-29 | The Trustees Of The University Of Pennsylvania | Novel antiviral compounds and methods using same |
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| US10323018B2 (en) | 2015-01-20 | 2019-06-18 | Millennium Pharmaceuticals, Inc. | Quinazoline and quinoline compounds and uses thereof |
| KR20200022027A (ko) * | 2017-06-30 | 2020-03-02 | 리부 세라퓨틱스 에스.에이. | 아데노신 A2A 수용체의 이미다조[1,2,a]피라진 조절물질 |
| EP3644998B1 (en) | 2017-06-30 | 2024-04-10 | Quixgen, Inc. | Novel spirolactone compounds |
| EP3643711A1 (en) * | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
| WO2021126729A1 (en) * | 2019-12-17 | 2021-06-24 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| ES3022307T3 (en) * | 2019-12-17 | 2025-05-28 | Merck Sharp & Dohme Llc | Prmt5 inhibitors |
| CN110981820B (zh) * | 2019-12-25 | 2023-05-19 | 上海彩迩文生化科技有限公司 | 一种酸性条件下合成喹喔啉-2-酮的方法 |
| WO2024036288A2 (en) * | 2022-08-11 | 2024-02-15 | Maplight Therapeutics, Inc. | Gpr6 inverse agonists |
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-
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- 2011-12-19 KR KR1020137016245A patent/KR20130133219A/ko not_active Ceased
- 2011-12-19 CA CA2818597A patent/CA2818597A1/en not_active Abandoned
- 2011-12-19 EP EP11851281.3A patent/EP2661428B1/en active Active
- 2011-12-19 AU AU2011349524A patent/AU2011349524B2/en not_active Ceased
- 2011-12-19 JP JP2013546270A patent/JP5952829B2/ja not_active Expired - Fee Related
- 2011-12-19 MX MX2013007295A patent/MX2013007295A/es not_active Application Discontinuation
- 2011-12-19 ES ES11851281.3T patent/ES2635030T3/es active Active
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- 2011-12-19 RU RU2013134334/04A patent/RU2589709C2/ru not_active IP Right Cessation
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- 2011-12-21 TW TW100147844A patent/TW201307302A/zh unknown
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| US7666878B2 (en) * | 2004-06-17 | 2010-02-23 | Novartis Ag | Pyrrolopyridine derivatives and their use as Crth2 antagonists |
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20130133219A (ko) | 2013-12-06 |
| RU2013134334A (ru) | 2015-01-27 |
| US9469615B2 (en) | 2016-10-18 |
| RU2589709C2 (ru) | 2016-07-10 |
| BR112013015397A2 (pt) | 2016-09-20 |
| US20130303517A1 (en) | 2013-11-14 |
| CN103702985A (zh) | 2014-04-02 |
| EP2661428A4 (en) | 2014-12-17 |
| MX2013007295A (es) | 2013-08-26 |
| TW201307302A (zh) | 2013-02-16 |
| EP2661428A1 (en) | 2013-11-13 |
| JP2014500323A (ja) | 2014-01-09 |
| CN103702985B (zh) | 2016-02-17 |
| AU2011349524A1 (en) | 2013-05-30 |
| CA2818597A1 (en) | 2012-06-28 |
| AR084573A1 (es) | 2013-05-29 |
| WO2012087861A1 (en) | 2012-06-28 |
| EP2661428B1 (en) | 2017-06-07 |
| JP5952829B2 (ja) | 2016-07-13 |
| ES2635030T3 (es) | 2017-10-02 |
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