AU2011323729B2 - Compositions and methods for the generation of platelets and methods of use thereof - Google Patents
Compositions and methods for the generation of platelets and methods of use thereof Download PDFInfo
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- AU2011323729B2 AU2011323729B2 AU2011323729A AU2011323729A AU2011323729B2 AU 2011323729 B2 AU2011323729 B2 AU 2011323729B2 AU 2011323729 A AU2011323729 A AU 2011323729A AU 2011323729 A AU2011323729 A AU 2011323729A AU 2011323729 B2 AU2011323729 B2 AU 2011323729B2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/23—Interleukins [IL]
- C12N2501/2311—Interleukin-11 (IL-11)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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| US40651410P | 2010-10-25 | 2010-10-25 | |
| US61/406,514 | 2010-10-25 | ||
| PCT/US2011/057716 WO2012061146A1 (en) | 2010-10-25 | 2011-10-25 | Compositions and methods for the generation of platelets and methods of use thereof |
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| AU2011323729A1 AU2011323729A1 (en) | 2013-05-30 |
| AU2011323729B2 true AU2011323729B2 (en) | 2016-08-04 |
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| AU (1) | AU2011323729B2 (https=) |
| CA (1) | CA2815426A1 (https=) |
| WO (1) | WO2012061146A1 (https=) |
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| GB201210857D0 (en) * | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
| US9074186B2 (en) | 2012-08-15 | 2015-07-07 | Boston Medical Center Corporation | Production of red blood cells and platelets from stem cells |
| CA2896053A1 (en) | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| WO2014138485A1 (en) * | 2013-03-08 | 2014-09-12 | Irm Llc | Ex vivo production of platelets from hematopoietic stem cells and the product thereof |
| US11319528B2 (en) | 2015-07-13 | 2022-05-03 | University Of Utah Research Foundation | Methods of making red blood cells and platelets in vitro and uses thereof |
| WO2018053288A1 (en) * | 2016-09-16 | 2018-03-22 | The Children's Hospital Of Philadelphia | Methods and compositions for identification and enrichment of platelet-producing megakaryocytes (mks) |
| JP2021509812A (ja) | 2018-01-05 | 2021-04-08 | プレートレット バイオジェネシス， インコーポレイテッド | 巨核球を産生するための組成物および方法 |
| EP3813853A4 (en) | 2018-06-29 | 2022-04-06 | Platelet Biogenesis, Inc. | DELIVERY COMPOSITIONS AND METHODS OF USE |
| JP2022512622A (ja) * | 2018-10-05 | 2022-02-07 | ユニヴァーシティー オブ ユタ リサーチ ファウンデーション | 改変受容体を含む血小板の作製方法及びその使用法 |
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| US5824297A (en) | 1990-06-25 | 1998-10-20 | Oncogene Science, Inc. | Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof |
| US5817662A (en) | 1992-11-09 | 1998-10-06 | Cell Therapeutics, Inc. | Substituted amino alkyl compounds |
| US5772992A (en) | 1992-11-24 | 1998-06-30 | G.D. Searle & Co. | Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors |
| US5571686A (en) | 1994-04-14 | 1996-11-05 | Massachusetts Institute Of Technology | Method of using megapoietin for prolonging the survival & viability of platlets |
| US6337387B1 (en) | 1995-11-17 | 2002-01-08 | Asahi Kasei Kabushiki Kaisha | Differentiation-suppressive polypeptide |
| US5811297A (en) | 1996-03-07 | 1998-09-22 | Amba Biosciences, Llc | Immortalized hematopoietic cell lines, cell system thereof with stromal cells, in vitro, ex vivo and in vivo uses, & in vitro generation of dendritic cells and macrophages |
| US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| AU720930B2 (en) | 1996-07-16 | 2000-06-15 | Asahi Kasei Kabushiki Kaisha | Differentiation inhibitor |
| US6066778A (en) | 1996-11-06 | 2000-05-23 | The Regents Of The University Of Michigan | Transgenic mice expressing APC resistant factor V |
| US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US6248587B1 (en) | 1997-11-26 | 2001-06-19 | University Of Southern Cailfornia | Method for promoting mesenchymal stem and lineage-specific cell proliferation |
| JPH11180877A (ja) | 1997-12-17 | 1999-07-06 | Asahi Chem Ind Co Ltd | 巨核球前駆細胞を含む細胞製剤及びその製造方法 |
| US6846647B1 (en) | 1998-04-28 | 2005-01-25 | Ono Pharmaceutical Co., Ltd. | Polypeptides suppressing smooth muscle cell proliferation, the encoding cDNA, and related methods |
| AU2221600A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| US6586390B1 (en) | 2000-01-21 | 2003-07-01 | Hyseq, Inc. | Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides |
| US6465620B1 (en) | 2000-01-21 | 2002-10-15 | Hyseq, Inc. | Methods and materials relating to novel von Willebrand/Thrombospondin-like polypeptides and polynucleotides |
| US6569662B1 (en) | 2000-01-21 | 2003-05-27 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US6673904B2 (en) | 2000-12-23 | 2004-01-06 | Kirin Beer Kabushiki Kaisha | Stem cell growth factor-like polypeptides |
| CA2450125A1 (en) | 2001-06-15 | 2002-12-27 | Andre C. Schuh | Gene therapy for hemophilia a |
| EP1420807A4 (en) | 2001-08-09 | 2005-08-17 | Cornell Res Foundation Inc | THROMBOZYTE GROWTH FACTOR FOR THE PROTECTION OF THE CARDIAL MYOKARD |
| EP1336846A1 (en) | 2002-02-13 | 2003-08-20 | Procorde GmbH | Method for generating recombinant human platelets for identifying therapeutic target proteins |
| JP2005522215A (ja) | 2002-04-12 | 2005-07-28 | セルジーン・コーポレーション | 幹細胞及び前駆細胞の分化のモジュレーション、アッセイ、並びにそれらの使用 |
| CN1668733A (zh) | 2002-05-30 | 2005-09-14 | 细胞基因公司 | 利用jnk或mkk抑制剂调节细胞分化并治疗骨髓增生异常和脊髓发育不良综合症的方法 |
| US7012005B2 (en) | 2002-06-25 | 2006-03-14 | Siliconix Incorporated | Self-aligned differential oxidation in trenches by ion implantation |
| WO2005103234A1 (en) | 2004-04-23 | 2005-11-03 | Héma-Québec | A new method of expanding cord blood cells |
| ZA200704252B (en) * | 2004-10-25 | 2009-09-30 | Cellerant Therapeutics Inc | Methods of expanding myeloid cell populations and uses thereof |
| US20070077654A1 (en) | 2004-11-01 | 2007-04-05 | Thomson James A | Platelets from stem cells |
| AU2005302258B2 (en) | 2004-11-01 | 2010-10-21 | Wisconsin Alumni Research Foundation | Platelets from stem cells |
| EP1958648A4 (en) * | 2005-10-28 | 2009-12-30 | Dnavec Corp | THERAPEUTIC PROCESS FOR BLOOD CLEANING DISORDER |
| WO2008137533A1 (en) * | 2007-05-04 | 2008-11-13 | Reddy Us Therapeutics, Inc. | Methods and compositions for upregulation of gata activity |
| WO2008151386A1 (en) | 2007-06-15 | 2008-12-18 | Australian Stem Cell Centre Ltd | Megakaryocyte differentiation |
| EP2315829B1 (en) | 2008-08-08 | 2015-02-11 | Mayo Foundation For Medical Education And Research | Induced pluripotent stem cells |
| AU2010319555A1 (en) | 2009-11-11 | 2012-06-14 | Sanford-Burnham Medical Research Institute | Method for generation and regulation of iPS cells and compositions thereof |
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2011
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- 2011-10-25 CA CA2815426A patent/CA2815426A1/en not_active Abandoned
- 2011-10-25 AU AU2011323729A patent/AU2011323729B2/en not_active Ceased
- 2011-10-25 US US13/881,587 patent/US9259443B2/en active Active
- 2011-10-25 EP EP11838540.0A patent/EP2633047A4/en not_active Withdrawn
- 2011-10-25 WO PCT/US2011/057716 patent/WO2012061146A1/en not_active Ceased
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| Title |
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| STACHURA, D., et al. Blood, 2006, vol. 107, pages 87-97 * |
Also Published As
| Publication number | Publication date |
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| WO2012061146A1 (en) | 2012-05-10 |
| EP2633047A4 (en) | 2014-04-02 |
| JP2014511118A (ja) | 2014-05-08 |
| EP2633047A1 (en) | 2013-09-04 |
| AU2011323729A1 (en) | 2013-05-30 |
| US20140086883A1 (en) | 2014-03-27 |
| JP6126004B2 (ja) | 2017-05-10 |
| US9259443B2 (en) | 2016-02-16 |
| CA2815426A1 (en) | 2012-05-10 |
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