AU2011213563B2 - Selective reduction of allelic variants - Google Patents

Selective reduction of allelic variants Download PDF

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Publication number
AU2011213563B2
AU2011213563B2 AU2011213563A AU2011213563A AU2011213563B2 AU 2011213563 B2 AU2011213563 B2 AU 2011213563B2 AU 2011213563 A AU2011213563 A AU 2011213563A AU 2011213563 A AU2011213563 A AU 2011213563A AU 2011213563 B2 AU2011213563 B2 AU 2011213563B2
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major
certain embodiments
antisense
wing
modified
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AU2011213563A1 (en
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C. Frank Bennett
Jeffrey Carroll
Susan M. Freier
Sarah Greenlee
Michael Hayden
Eric E. Swayze
Simon Warby
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University of British Columbia
Ionis Pharmaceuticals Inc
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Ionis Pharmaceuticals Inc
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Assigned to IONIS PHARMACEUTICALS, INC., THE UNIVERSITY OF BRITISH COLUMBIA reassignment IONIS PHARMACEUTICALS, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: ISIS PHARMACEUTICALS, INC., THE UNIVERSITY OF BRITISH COLUMBIA
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    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/34—Allele or polymorphism specific uses
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    • C12Q2539/00—Reactions characterised by analysis of gene expression or genome comparison
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
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  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2011213563A 2010-02-08 2011-02-08 Selective reduction of allelic variants Active AU2011213563B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30245810P 2010-02-08 2010-02-08
US61/302,458 2010-02-08
US37164010P 2010-08-06 2010-08-06
US61/371,640 2010-08-06
PCT/US2011/024104 WO2011097644A2 (en) 2010-02-08 2011-02-08 Selective reduction of allelic variants

Publications (2)

Publication Number Publication Date
AU2011213563A1 AU2011213563A1 (en) 2012-08-23
AU2011213563B2 true AU2011213563B2 (en) 2015-12-24

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AU2011213563A Active AU2011213563B2 (en) 2010-02-08 2011-02-08 Selective reduction of allelic variants

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US (5) US9006198B2 (enExample)
EP (3) EP2534262B1 (enExample)
JP (1) JP6018506B2 (enExample)
AU (1) AU2011213563B2 (enExample)
CA (1) CA2789038A1 (enExample)
IL (1) IL221271A (enExample)
WO (1) WO2011097644A2 (enExample)

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