AU2010359346B2 - Phospholipid depot - Google Patents
Phospholipid depot Download PDFInfo
- Publication number
- AU2010359346B2 AU2010359346B2 AU2010359346A AU2010359346A AU2010359346B2 AU 2010359346 B2 AU2010359346 B2 AU 2010359346B2 AU 2010359346 A AU2010359346 A AU 2010359346A AU 2010359346 A AU2010359346 A AU 2010359346A AU 2010359346 B2 AU2010359346 B2 AU 2010359346B2
- Authority
- AU
- Australia
- Prior art keywords
- depot
- water
- viscosity
- vancomycin
- gentamicin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000003904 phospholipids Chemical class 0.000 title claims abstract description 53
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
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- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 1
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- AERBNCYCJBRYDG-KSZLIROESA-N phytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO AERBNCYCJBRYDG-KSZLIROESA-N 0.000 description 1
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- FGGPAWQCCGEWTJ-UHFFFAOYSA-M sodium;2,3-bis(sulfanyl)propane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CC(S)CS FGGPAWQCCGEWTJ-UHFFFAOYSA-M 0.000 description 1
- YNQYZBDRJZVSJE-UHFFFAOYSA-M sodium;2,3-dihydroxypropyl 2,3-di(octadecanoyloxy)propyl phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCCCC YNQYZBDRJZVSJE-UHFFFAOYSA-M 0.000 description 1
- QLNOOKSBAYIHQI-SKZICHJRSA-M sodium;2,3-dihydroxypropyl [(2r)-2,3-di(tetradecanoyloxy)propyl] phosphate Chemical compound [Na+].CCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCC QLNOOKSBAYIHQI-SKZICHJRSA-M 0.000 description 1
- IUVFCFQZFCOKRC-IPKKNMRRSA-M sodium;[(2r)-2,3-bis[[(z)-octadec-9-enoyl]oxy]propyl] 2,3-dihydroxypropyl phosphate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C/CCCCCCCC IUVFCFQZFCOKRC-IPKKNMRRSA-M 0.000 description 1
- LDWIWSHBGAIIMV-ODZMYOIVSA-M sodium;[(2r)-2,3-di(hexadecanoyloxy)propyl] 2,3-dihydroxypropyl phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCC LDWIWSHBGAIIMV-ODZMYOIVSA-M 0.000 description 1
- ALPWRKFXEOAUDR-GKEJWYBXSA-M sodium;[(2r)-2,3-di(octadecanoyloxy)propyl] hydrogen phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC ALPWRKFXEOAUDR-GKEJWYBXSA-M 0.000 description 1
- ALPWRKFXEOAUDR-JFRIYMKVSA-M sodium;[(2s)-2,3-di(octadecanoyloxy)propyl] hydrogen phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC ALPWRKFXEOAUDR-JFRIYMKVSA-M 0.000 description 1
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- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
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- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
- Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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Priority Applications (1)
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| AU2015202240A AU2015202240B2 (en) | 2010-08-20 | 2015-04-29 | Phospholipid depot |
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| US37550210P | 2010-08-20 | 2010-08-20 | |
| US61/375,502 | 2010-08-20 | ||
| PCT/US2010/061015 WO2012023955A1 (en) | 2010-08-20 | 2010-12-17 | Phospholipid depot |
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| AU2010359346A1 AU2010359346A1 (en) | 2013-04-04 |
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| US11337894B2 (en) | 2018-06-15 | 2022-05-24 | James T. Doubet | Syringe adapter for animal medication |
| US11090444B2 (en) | 2018-06-15 | 2021-08-17 | James T. Doubet | Syringe adapter for medication |
| US11097058B2 (en) | 2018-06-15 | 2021-08-24 | James T. Doubet | Syringe adapter for medication |
| US10709850B2 (en) | 2018-06-15 | 2020-07-14 | James T. Doubet | Syringe adapter for medication |
| ES2798263T3 (es) | 2005-12-08 | 2020-12-10 | Insmed Inc | Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| AU2010359346B2 (en) * | 2010-08-20 | 2015-01-29 | Dr. Reddy's Laboratories Sa | Phospholipid depot |
| EP2629779B1 (en) * | 2010-10-22 | 2017-06-21 | Dr. Reddy's Laboratories SA. | Use of storage stable viscous phospholipid depot to treat wounds |
| CN104427977B (zh) | 2012-05-10 | 2018-02-02 | 佩因拉佛姆有限公司 | 局部麻醉剂的储库制剂及其制备方法 |
| CA2891487A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| WO2015161065A1 (en) * | 2014-04-16 | 2015-10-22 | Biomet Manufacturing, Llc | Methods for coating implant surfaces to treat surgical infections |
| WO2015158823A1 (de) | 2014-04-16 | 2015-10-22 | Veyx-Pharma Gmbh | Veterinärpharmazeutische zusammensetzung und deren verwendung |
| AU2015253417B2 (en) | 2014-04-28 | 2020-02-20 | Dimerx, Inc. | Pharmaceutically active dimers linked through phenolic hydroxyl groups |
| MX384843B (es) | 2014-05-15 | 2025-03-14 | Insmed Inc | Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas. |
| US20170165374A1 (en) * | 2015-11-18 | 2017-06-15 | Insmed, Inc. | Compositions and methods for treating bacterial infections |
| CN107522735A (zh) * | 2017-09-21 | 2017-12-29 | 安徽元创科技有限公司 | 以溶剂法生产低粘度磷脂产品的方法 |
| EP3773505B1 (en) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| EP3787602A4 (en) | 2018-05-02 | 2022-03-23 | Insmed Incorporated | PROCESS FOR THE MANUFACTURE OF LIPOSOMAL DRUG FORMULATIONS |
| USD1126398S1 (en) | 2018-06-15 | 2026-05-12 | James T. Doubet | Syringe adapter for medication |
| USD890925S1 (en) | 2018-06-15 | 2020-07-21 | James T. Doubet | Syringe adapter for medication |
| US20190388625A1 (en) | 2018-06-15 | 2019-12-26 | James T. Doubet | Syringe adapter for medication |
| CA3110931A1 (en) * | 2018-10-21 | 2020-04-30 | James T. DOUBET | Syringe adapter for medication |
| WO2020146788A1 (en) * | 2019-01-11 | 2020-07-16 | University Of Washington | Combination pharmaceutical compositions and methods thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007133711A2 (en) * | 2006-05-12 | 2007-11-22 | Adventrx Pharmaceuticals, Inc. | Pharmaceutical compositions for vein irritating drugs |
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|---|---|---|---|---|
| US4252793A (en) | 1979-06-18 | 1981-02-24 | American Lecithin Company | Injectable lecithin preparation |
| NZ223660A (en) | 1987-03-05 | 1990-11-27 | Liposome Co Inc | Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity |
| CH681427A5 (enExample) | 1987-07-01 | 1993-03-31 | Zambon Spa | |
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2010
- 2010-12-17 AU AU2010359346A patent/AU2010359346B2/en not_active Ceased
- 2010-12-17 EP EP10795596.5A patent/EP2605751A1/en not_active Withdrawn
- 2010-12-17 JP JP2013524832A patent/JP5752248B2/ja not_active Expired - Fee Related
- 2010-12-17 WO PCT/US2010/061015 patent/WO2012023955A1/en not_active Ceased
- 2010-12-17 NZ NZ608210A patent/NZ608210A/en not_active IP Right Cessation
- 2010-12-17 KR KR1020137006779A patent/KR101793101B1/ko not_active Expired - Fee Related
- 2010-12-17 MX MX2013002005A patent/MX366099B/es active IP Right Grant
- 2010-12-17 CA CA2809022A patent/CA2809022C/en active Active
- 2010-12-17 CN CN201080069723.7A patent/CN103179951B/zh not_active Expired - Fee Related
- 2010-12-17 BR BR112013003934A patent/BR112013003934A2/pt active Search and Examination
- 2010-12-17 RU RU2013112353/15A patent/RU2595865C2/ru active
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2011
- 2011-09-23 US US13/242,778 patent/US9132144B2/en not_active Expired - Fee Related
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2013
- 2013-03-11 ZA ZA2013/01833A patent/ZA201301833B/en unknown
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2015
- 2015-07-07 US US14/793,552 patent/US9522169B2/en not_active Expired - Fee Related
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2016
- 2016-11-10 US US15/347,949 patent/US9682040B2/en not_active Expired - Fee Related
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2017
- 2017-05-15 US US15/595,248 patent/US20170246109A1/en not_active Abandoned
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| WO2007133711A2 (en) * | 2006-05-12 | 2007-11-22 | Adventrx Pharmaceuticals, Inc. | Pharmaceutical compositions for vein irritating drugs |
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|---|---|
| US20120046220A1 (en) | 2012-02-23 |
| MX2013002005A (es) | 2013-06-24 |
| EP2605751A1 (en) | 2013-06-26 |
| ZA201301833B (en) | 2014-05-28 |
| US9682040B2 (en) | 2017-06-20 |
| CN103179951B (zh) | 2016-01-20 |
| US20170056326A1 (en) | 2017-03-02 |
| JP5752248B2 (ja) | 2015-07-22 |
| CA2809022A1 (en) | 2012-02-23 |
| US20150306173A1 (en) | 2015-10-29 |
| KR20130112870A (ko) | 2013-10-14 |
| RU2595865C2 (ru) | 2016-08-27 |
| KR101793101B1 (ko) | 2017-11-02 |
| AU2010359346A1 (en) | 2013-04-04 |
| US9132144B2 (en) | 2015-09-15 |
| NZ608210A (en) | 2015-02-27 |
| US20170246109A1 (en) | 2017-08-31 |
| JP2013534244A (ja) | 2013-09-02 |
| MX366099B (es) | 2019-06-27 |
| CN103179951A (zh) | 2013-06-26 |
| BR112013003934A2 (pt) | 2016-06-07 |
| WO2012023955A1 (en) | 2012-02-23 |
| US9522169B2 (en) | 2016-12-20 |
| RU2013112353A (ru) | 2014-09-27 |
| CA2809022C (en) | 2017-01-03 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: DR. REDDY'S LABORATORIES SA Free format text: FORMER OWNER(S): DR. REDDY'S LABORATORIES, LTD. |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |