AU2010319697B2 - Mammalian metabolites of steroids - Google Patents
Mammalian metabolites of steroids Download PDFInfo
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- AU2010319697B2 AU2010319697B2 AU2010319697A AU2010319697A AU2010319697B2 AU 2010319697 B2 AU2010319697 B2 AU 2010319697B2 AU 2010319697 A AU2010319697 A AU 2010319697A AU 2010319697 A AU2010319697 A AU 2010319697A AU 2010319697 B2 AU2010319697 B2 AU 2010319697B2
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- prostate cancer
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Classifications
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Landscapes
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- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26126209P | 2009-11-13 | 2009-11-13 | |
| US61/261,262 | 2009-11-13 | ||
| PCT/US2010/055996 WO2011059969A2 (en) | 2009-11-13 | 2010-11-09 | Mammalian metabolites of steroids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2010319697A1 AU2010319697A1 (en) | 2012-06-07 |
| AU2010319697B2 true AU2010319697B2 (en) | 2016-05-19 |
Family
ID=43992357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2010319697A Ceased AU2010319697B2 (en) | 2009-11-13 | 2010-11-09 | Mammalian metabolites of steroids |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20120282331A1 (OSRAM) |
| EP (1) | EP2499151A4 (OSRAM) |
| JP (1) | JP5956928B2 (OSRAM) |
| CN (1) | CN102822190B (OSRAM) |
| AU (1) | AU2010319697B2 (OSRAM) |
| BR (1) | BR112012012167A2 (OSRAM) |
| CA (1) | CA2780365A1 (OSRAM) |
| WO (1) | WO2011059969A2 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100048524A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| CN102686600A (zh) | 2009-02-05 | 2012-09-19 | 托凯药业股份有限公司 | 甾体cyp17抑制剂/抗雄激素物质的新型药物前体 |
| WO2010149755A1 (en) | 2009-06-26 | 2010-12-29 | Novartis Ag | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17 |
| AU2012249421B9 (en) | 2011-04-28 | 2015-10-22 | Novartis Ag | 17alpha-hydroxylase/C17,20-lyase inhibitors |
| CA2904170A1 (en) * | 2013-03-14 | 2014-09-25 | University Of Maryland, Baltimore | Androgen receptor down-regulating agents and uses thereof |
| JP2016528252A (ja) | 2013-08-12 | 2016-09-15 | トーカイ ファーマシューティカルズ， インコーポレイテッド | アンドロゲン標的治療を使用する新生物障害の処置のためのバイオマーカー |
| US10675289B2 (en) | 2014-10-02 | 2020-06-09 | University Of Maryland, Baltimore | Methods of treating pancreatic cancer |
| CN105732759A (zh) * | 2015-01-29 | 2016-07-06 | 苏州晶云药物科技有限公司 | (3β)-17-(1H-苯并咪唑-1-基)雄甾-5，16-二烯-3-醇的盐及其制备方法 |
| CN112851741B (zh) * | 2016-02-19 | 2022-10-25 | 深圳市塔吉瑞生物医药有限公司 | 一种取代的甾体类化合物及其应用 |
| CN111454315B (zh) * | 2020-04-15 | 2022-12-09 | 宁波第二激素厂 | 一种雄甾-16-烯-3β-醇的合成方法 |
| CN116621902A (zh) * | 2022-05-18 | 2023-08-22 | 上海醇健实业发展有限公司 | 17-苯并咪唑基-10α-甲基-甾体衍生物及其制备方法、用途和药物组合物 |
Citations (1)
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|---|---|---|---|---|
| WO2006093993A1 (en) * | 2005-03-02 | 2006-09-08 | University Of Maryland | Novel c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3480621A (en) * | 1967-01-17 | 1969-11-25 | Phytogen Prod Inc | Steroid ketal |
| WO1993020097A1 (en) * | 1992-03-31 | 1993-10-14 | British Technology Group Ltd. | 17-substituted steroids useful in cancer treatment |
| DE4232681C2 (de) * | 1992-09-29 | 1994-11-24 | Sigma Tau Ind Farmaceuti | 17-Phenyl- und 17-Furyl-14beta,5alpha-androstan- und androsten- Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung |
| WO2009114658A2 (en) * | 2008-03-12 | 2009-09-17 | University Of Maryland, Baltimore | Androgen receptor inactivation contributes to antitumor efficacy of cyp17 inhibitors in prostate cancer |
| GB2470700B (en) * | 2008-03-25 | 2012-08-08 | Univ Maryland | C-17 heteroaryl steroidal CYP17 inhibitors |
| WO2010091299A2 (en) * | 2009-02-05 | 2010-08-12 | Tokai Pharmaceuticals | Novel combination cancer therapies |
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2010
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- 2010-11-09 CN CN201080059467.3A patent/CN102822190B/zh not_active Expired - Fee Related
- 2010-11-09 US US13/508,726 patent/US20120282331A1/en not_active Abandoned
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- 2010-11-09 EP EP10830591A patent/EP2499151A4/en not_active Withdrawn
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- 2010-11-09 AU AU2010319697A patent/AU2010319697B2/en not_active Ceased
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006093993A1 (en) * | 2005-03-02 | 2006-09-08 | University Of Maryland | Novel c-17-heteroaryl steroidal cyp17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity |
Non-Patent Citations (1)
| Title |
|---|
| HANDRATTA et al., Journal of Medicinal Chemistry, 2005, Vol. 48, No. 8, Pages 2972-2984 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2499151A2 (en) | 2012-09-19 |
| BR112012012167A2 (pt) | 2017-10-03 |
| US20170008920A1 (en) | 2017-01-12 |
| WO2011059969A2 (en) | 2011-05-19 |
| US20120282331A1 (en) | 2012-11-08 |
| CN102822190A (zh) | 2012-12-12 |
| EP2499151A4 (en) | 2013-03-20 |
| WO2011059969A3 (en) | 2011-09-22 |
| JP2013510856A (ja) | 2013-03-28 |
| CN102822190B (zh) | 2016-03-30 |
| AU2010319697A1 (en) | 2012-06-07 |
| CA2780365A1 (en) | 2011-05-19 |
| JP5956928B2 (ja) | 2016-07-27 |
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