AU2009331526B2 - Polyunsaturated fatty acid and diol ester as an anti-acne agent - Google Patents
Polyunsaturated fatty acid and diol ester as an anti-acne agent Download PDFInfo
- Publication number
- AU2009331526B2 AU2009331526B2 AU2009331526A AU2009331526A AU2009331526B2 AU 2009331526 B2 AU2009331526 B2 AU 2009331526B2 AU 2009331526 A AU2009331526 A AU 2009331526A AU 2009331526 A AU2009331526 A AU 2009331526A AU 2009331526 B2 AU2009331526 B2 AU 2009331526B2
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- Australia
- Prior art keywords
- acid
- compound
- polyunsaturated fatty
- formula
- fatty acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title claims abstract description 52
- -1 diol ester Chemical class 0.000 title claims description 17
- 239000000058 anti acne agent Substances 0.000 title description 3
- 229940124340 antiacne agent Drugs 0.000 title description 3
- 150000001875 compounds Chemical class 0.000 claims abstract description 40
- 206010000496 acne Diseases 0.000 claims abstract description 38
- 208000002874 Acne Vulgaris Diseases 0.000 claims abstract description 36
- 239000000203 mixture Substances 0.000 claims abstract description 30
- 238000000034 method Methods 0.000 claims abstract description 18
- 239000002537 cosmetic Substances 0.000 claims abstract description 16
- 208000008742 seborrheic dermatitis Diseases 0.000 claims abstract description 14
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims abstract description 13
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims description 24
- 150000002009 diols Chemical class 0.000 claims description 15
- 235000021342 arachidonic acid Nutrition 0.000 claims description 12
- 229940114079 arachidonic acid Drugs 0.000 claims description 12
- 238000005859 coupling reaction Methods 0.000 claims description 12
- PSHKMPUSSFXUIA-UHFFFAOYSA-N n,n-dimethylpyridin-2-amine Chemical compound CN(C)C1=CC=CC=N1 PSHKMPUSSFXUIA-UHFFFAOYSA-N 0.000 claims description 11
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims description 10
- DTOSIQBPPRVQHS-UHFFFAOYSA-N α-Linolenic acid Chemical compound CCC=CCC=CCC=CCCCCCCCC(O)=O DTOSIQBPPRVQHS-UHFFFAOYSA-N 0.000 claims description 9
- OPGOLNDOMSBSCW-CLNHMMGSSA-N Fursultiamine hydrochloride Chemical compound Cl.C1CCOC1CSSC(\CCO)=C(/C)N(C=O)CC1=CN=C(C)N=C1N OPGOLNDOMSBSCW-CLNHMMGSSA-N 0.000 claims description 8
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- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims description 7
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims description 7
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0858967 | 2008-12-22 | ||
| FR0858967A FR2940281B1 (fr) | 2008-12-22 | 2008-12-22 | Ester de diol et d'acide gras polyinsature comme agent anti-acne |
| PCT/EP2009/067701 WO2010072738A1 (fr) | 2008-12-22 | 2009-12-21 | Ester de diol et d'acide gras polyinsature comme agent anti-acne |
Publications (2)
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| AU2009331526A1 AU2009331526A1 (en) | 2010-07-01 |
| AU2009331526B2 true AU2009331526B2 (en) | 2013-10-24 |
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| AU2009331526A Ceased AU2009331526B2 (en) | 2008-12-22 | 2009-12-21 | Polyunsaturated fatty acid and diol ester as an anti-acne agent |
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| EP (1) | EP2379484B1 (enExample) |
| JP (1) | JP5587333B2 (enExample) |
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| CN (1) | CN102256930B (enExample) |
| AU (1) | AU2009331526B2 (enExample) |
| BR (1) | BRPI0923494B1 (enExample) |
| CA (1) | CA2747681C (enExample) |
| CL (1) | CL2011001539A1 (enExample) |
| CO (1) | CO6390033A2 (enExample) |
| ES (1) | ES2424088T3 (enExample) |
| FR (1) | FR2940281B1 (enExample) |
| GE (1) | GEP20135820B (enExample) |
| IL (1) | IL213646A (enExample) |
| MA (1) | MA32810B1 (enExample) |
| MX (1) | MX2011006659A (enExample) |
| MY (1) | MY151002A (enExample) |
| NZ (1) | NZ593781A (enExample) |
| PL (1) | PL2379484T3 (enExample) |
| PT (1) | PT2379484E (enExample) |
| RU (1) | RU2524779C2 (enExample) |
| SG (1) | SG172342A1 (enExample) |
| TN (1) | TN2011000237A1 (enExample) |
| UA (1) | UA103645C2 (enExample) |
| WO (1) | WO2010072738A1 (enExample) |
| ZA (1) | ZA201103509B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9907812B2 (en) | 2011-06-22 | 2018-03-06 | Vyome Biosciences Pvt. Ltd. | Conjugate-based antifungal and antibacterial prodrugs |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2983858B1 (fr) * | 2011-12-08 | 2014-01-03 | Fabre Pierre Dermo Cosmetique | Nouveaux composes inhibiteurs de la lipogenese |
| CA2920457A1 (en) * | 2013-08-08 | 2015-02-12 | Galderm Therapeutics Ltd. | Anti-acne compositions comprising bile acid-fatty acid conjugates |
| FR3033135B1 (fr) * | 2015-02-27 | 2018-03-16 | Pierre Fabre Dermo-Cosmetique | Association d'un retinoide et d'un ester de diol et d'acide gras polyinsature |
| FR3053253B1 (fr) * | 2016-07-01 | 2020-01-17 | Pierre Fabre Dermo-Cosmetique | Nouvel extrait d'akenes de silybum marianum et ses utilisations en dermatologie et dermo-cosmetique |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1998013330A1 (en) * | 1996-09-26 | 1998-04-02 | Scotia Holdings Plc | Esters of unsaturated fatty acids |
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| JPS5534762B2 (enExample) | 1975-02-07 | 1980-09-09 | ||
| DE4240674C2 (de) | 1992-11-26 | 1999-06-24 | Schuelke & Mayr Gmbh | Desodorierende Wirkstoffe |
| AU683027B2 (en) * | 1993-01-27 | 1997-10-30 | Scotia Holdings Plc | Triglycerides |
| MY118354A (en) | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
| JPH09110818A (ja) * | 1995-10-16 | 1997-04-28 | Sanshin Chem Ind Co Ltd | １−エチル−３−（３−ジメチルアミノプロピル）カルボジイミド塩酸塩の製造方法 |
| ES2176692T3 (es) | 1996-02-21 | 2002-12-01 | Stoa Sa | Composiciones cosmeticas, dermofarmaceuticas o veterinarias para el tratamiento aseptico de la piel humana o animal. |
| GB9622636D0 (en) | 1996-10-30 | 1997-01-08 | Scotia Holdings Plc | Presentation of bioactives |
| GB9710351D0 (en) * | 1997-05-20 | 1997-07-16 | Scotia Holdings Plc | Glucosamine fatty acids |
| WO2001001980A1 (en) * | 1999-07-06 | 2001-01-11 | The Regents Of The University Of California | Methods for the amelioration of neuropsychiatric disorders by inhibiting the inactivating transport of endogenous cannabinoid substances |
| GB9927629D0 (en) * | 1999-11-24 | 2000-01-19 | Croda Int Plc | Compounds |
| ES2208498T3 (es) | 2001-06-22 | 2004-06-16 | SYMRISE GMBH & CO. KG | Uso de 1,2-decanodiol contra germenes causantes de olores corporales desagradables. |
| US20070265352A1 (en) | 2002-02-19 | 2007-11-15 | Joachim Roeding | Synergistic mixtures of at least one 1,2 alkanediol such as 1,2-hexanediol and 1,2-octanediol with a further compound having antimicrobial properties |
| DE10206759A1 (de) | 2002-02-19 | 2003-08-28 | Dragoco Gerberding Co Ag | Synergistische Mischungen von 1,2-Alkandiolen |
| SE0301862D0 (sv) | 2003-06-26 | 2003-06-26 | Jan Faergeman | Sätt att inhibera tillväxten av mot antibiotika resistenta bakterier |
| DE102004031210A1 (de) * | 2004-06-28 | 2006-02-09 | Trommsdorff Gmbh & Co. Kg | MLV-Kosmetikum |
| DE10341179A1 (de) | 2003-09-06 | 2005-03-31 | Beiersdorf Ag | Wirkstoffkombination gegen Akne |
| US7935732B2 (en) | 2004-04-08 | 2011-05-03 | Isp Investments Inc. | Antimicrobial compositions |
| ES2352744T3 (es) * | 2004-04-27 | 2011-02-22 | Akzo Nobel Coatings International Bv | Pintura pigmentada que se desprende a tiras. |
| JP2006056795A (ja) * | 2004-08-18 | 2006-03-02 | Suntory Ltd | ６−ｏ−ｐｕｆａアスコルビン酸エステルを含有する皮膚化粧料並びに飲食品 |
| DE102006044849A1 (de) * | 2006-09-22 | 2008-04-03 | Symrise Gmbh & Co. Kg | Dekonjugierte Alkadiensäureester als Riech- und/oder Aromastoffe |
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2008
- 2008-12-22 FR FR0858967A patent/FR2940281B1/fr not_active Expired - Fee Related
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2009
- 2009-12-21 CA CA2747681A patent/CA2747681C/fr active Active
- 2009-12-21 ES ES09797045T patent/ES2424088T3/es active Active
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998013330A1 (en) * | 1996-09-26 | 1998-04-02 | Scotia Holdings Plc | Esters of unsaturated fatty acids |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9907812B2 (en) | 2011-06-22 | 2018-03-06 | Vyome Biosciences Pvt. Ltd. | Conjugate-based antifungal and antibacterial prodrugs |
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